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QTL mapping of a natural genetic polymorphism for long-term parasite persistence in Daphnia populations

Published online by Cambridge University Press:  24 August 2017

MICHELLE KREBS ,
JARKKO ROUTTU  and
DIETER EBERT Open the ORCID record for DIETER EBERT [Opens in a new window]
MICHELLE KREBS
Affiliation:
Zoological Institute, Basel University, Vesalgasse 1, Basel, Switzerland
JARKKO ROUTTU
Affiliation:
Zoological Institute, Basel University, Vesalgasse 1, Basel, Switzerland Molecular Ecology, Martin-Luther-Universität, Halle-Wittenberg, Germany
DIETER EBERT*
Affiliation:
Zoological Institute, Basel University, Vesalgasse 1, Basel, Switzerland
*
*Corresponding author: Zoological Institute, Basel University, Vesalgasse 1, Basel, Switzerland. E-mail: [email protected]
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Summary

Knowing the determinants of the geographic ranges of parasites is important for understanding their evolutionary ecology, epidemiology and their potential to expand their range. Here we explore the determinants of geographic range in the peculiar case of a parasite species – the microsporidian Hamiltosporidium tvaerminnensis – that has a limited geographic distribution in a wide-spread host – Daphnia magna. We conducted a quantitative trait loci (QTLs) analysis with monoclonal F2D. magna populations originating from a cross between a susceptible northern European genotype and a resistant central European genotype. Contrary to our expectations, long-term persistence turned out to be a quantitative trait across the F2 offspring. Evidence for two QTLs, one epistatic interaction and for further minor QTL was found. This finding contrasts markedly with the previously described bimodal pattern for long-term parasite persistence in natural host genotypes across Europe and leaves open the question of how a quantitative genetic trait could determine the disjunct geographic distribution of the parasite across Europe.

Keywords

resistanceQTL analysismicrosporidiaDaphniaplanktoncrustaceaparasite persistence
Type
Research Article
Information
Parasitology , Volume 144 , Issue 13 , November 2017 , pp. 1686 - 1694
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Copyright
Copyright © Cambridge University Press 2017 

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