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Effects of host characteristics and parasite intensity on growth and fecundity of Trichostrongylus retortaeformis infections in rabbits

Published online by Cambridge University Press:  07 January 2009

C. CHYLINSKI ,
B. BOAG ,
M. J. STEAR  and
I. M. CATTADORI
C. CHYLINSKI
Affiliation:
Division of Animal Production and Public Health, Faculty of Veterinary Medicine, The University of Glasgow, GlasgowG61 1QH, UK
B. BOAG
Affiliation:
Division of Animal Production and Public Health, Faculty of Veterinary Medicine, The University of Glasgow, GlasgowG61 1QH, UK
M. J. STEAR
Affiliation:
Division of Animal Production and Public Health, Faculty of Veterinary Medicine, The University of Glasgow, GlasgowG61 1QH, UK
I. M. CATTADORI*
Affiliation:
Division of Animal Production and Public Health, Faculty of Veterinary Medicine, The University of Glasgow, GlasgowG61 1QH, UK Center for Infectious Disease Dynamics, Department of Biology 208 Mueller Laboratory, The Pennsylvania State University, University Park, PA16802, USA
*
*Corresponding author: Division of Animal Production and Public Health, Faculty of Veterinary Medicine, Glasgow University, GlasgowG61 1QH, UK. E-mail: [email protected]
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Summary

Host-mediated responses and parasite density-dependent processes can have a major influence on the growth and fecundity of parasitic nematodes. However, host characteristics and parasite intensity consistently change during the course of an infection and these could affect worm length and number of eggs in a non-constant way. We used a free-living population of rabbits naturally infected with Trichostronglyus retortateformis and examined how adult nematode length and the number of eggs in utero were affected by host characteristics (i.e. age, sex, breeding status) and parasite intensity, in a seasonal environment, between 2004 and 2007. Nematode length and number of eggs in utero decreased exponentially with host age; in contrast, parasite intensity increased, peaked in juveniles and decreased in older hosts. These patterns were consistent between rabbit cohorts. A negative relationship was observed between parasite intensity and nematode length, as well as number of eggs. Nematode length was strongly affected by nematode sex and host age, while the number of eggs was mainly influenced by nematode length. The direct influence of host-mediated effects appeared quantitatively more important than parasite density dependence in controlling length and egg production in naturally infected wild rabbits. However, their relative contribution changed during the course of the infection such that, while host immunity still influenced worm numbers, the direct effect of density-dependent interactions contributed the most at high parasite intensities.

Keywords

Trichostronglyus retortaeformisbody lengthnumber of eggs in uterohost-mediated effectsparasite density dependenceseasonality
Type
Research Article
Information
Parasitology , Volume 136 , Issue 1 , January 2009 , pp. 117 - 123
Copyright
Copyright © 2009 Cambridge University Press

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References

REFERENCES

Audebert, F., Cassone, J., Hoste, H. and Durrete-Desset, M. C. (2000). Morphogenesis and distribution of Trichostrongylus retortaeformis in the intestine of the rabbit. Journal of Helminthology 74, 95–107.CrossRefGoogle ScholarPubMed
Audebert, F., Vuong, P. N. and Durette-Desset, M. C. (2003). Intestinal migrations of Trichostrongylus retortaeformis (Trichostrongylina, Trichostrongylidae) in the rabbit. Veterinary Research 112, 131–146.Google ScholarPubMed
Barker, I. K. and Ford, G. E. (1975). Development and distribution of atrophic enteritis in the small intestines of rabbits infected with Trichostrongylus retortaeformis. Journal of Comparative Pathology 85, 427–435.CrossRefGoogle Scholar
Bleay, C., Ilkes, C. P., Paterson, S. and Viney, M. E. (2007). Density-dependent immune responses against the gastrointestinal nematode Strongyloides ratii. International Journal for Parasitology 37, 1501–1509.CrossRefGoogle Scholar
Cattadori, I. M., Albert, R. and Boag, B. (2007). Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits. Journal of the Royal Society Interface 4, 831–840.CrossRefGoogle ScholarPubMed
Cattadori, I. M., Boag, B., Bjørnstad, O. N., Cornell, S. and Hudson, P. J. (2005). Immuno-epidemiology and peak shift in a seasonal host-nematode system. Proceedings of the Royal Society of London, B 272, 1163–1169.Google Scholar
Cattadori, I. M., Boag, B. and Hudson, P. J. (2008). Parasite co-infection and interaction as drivers of host heterogeneity. International Journal for Parasitology 38, 371–380.CrossRefGoogle ScholarPubMed
Cornell, S., Bjørnstad, O. N., Cattadori, I. M., Boag, B. and Hudson, P. J. (2008). Seasonality, cohort-dependence and the development of immunity in a natural host-nematode system. Proceedings of the Royal Society of London, B 275, 473–591.Google Scholar
Gulland, F. M. D. (1992). The role of nematode parasites in Soay sheep (Ovis aries L.) mortality during a population crash. Parasitology 105, 493–503.CrossRefGoogle ScholarPubMed
Hastie, T. J. and Tibshirani, R. J. (1990). Generalized Additive Models. Chapman and Hall, London.Google Scholar
Haupt, W. (1975). Course of Trichostrongylus retortaeformis (Zeder, 1800) Looss, 1905, infestation in the domesic rabbit (Oryctolagus cuniculus). Archiv für experimentelle Veterinärmedizin 29, 135–141.Google Scholar
Henderson, N. G and Stear, M. J. (2006). Eosinophil and IgA responses in sheep infected with Teladorsagia circumcincta. Veterinary Immunology and Immunopathology 112, 62–66.CrossRefGoogle ScholarPubMed
Irvine, R. J., Stien, A., Dallas, J. F., Halvorsen, O., Langvatn, R. and Albon, S. D. (2001). Contrasting regulation of fecundity in two abomasal nematodes of Svalbard reindeer (Rangifer tarandus platyrhyncus). Parasitology 122, 673–681.CrossRefGoogle Scholar
Irvine, R. J., Stien, A., Halvorsen, O., Langvatn, R. and Albon, S. D. (2000). Life-history strategies and population dynamics of abomasal nematodes in Svalbard reindeer (Rangifer tarandus platyrhynchus). Parasitology 120, 297–311.CrossRefGoogle ScholarPubMed
Michael, E. and Bundy, D. A. P. (1989). Density dependence in establishment, growth and worm fecundity in intestinal helminthiasis: the population biology of Trichuris muris (Nematoda) infection in CBA/Ca mice. Parasitology 98, 451–458.CrossRefGoogle ScholarPubMed
Michel, J. F. (1952). Inhibition of development of Trichostrongylus retortaeformis. Nature 169, 933.CrossRefGoogle ScholarPubMed
Moqbel, R. and McLaren, D. J. (1980). Strongyloides ratti: Structural and functional characteristics of normal and immune-damaged worms. Experimental Parasitology 49, 139–152.CrossRefGoogle ScholarPubMed
Paterson, S. and Viney, M. E. (2002). Host immune responses are necessary for density dependence in nematode infections. Parasitology 125, 283–292.CrossRefGoogle ScholarPubMed
Richards, D. T. and Lewis, J. W. (2001). Fecundity and egg output by Toxocara canis in the red fox, Vulpes vulpes. Journal of Helminthology 75, 157–164.Google ScholarPubMed
Stear, M. J. and Bishop, S. C. (1999). The curvilinear relationship between worm length and fecundity of Teladorsagia circumcincta. International Journal for Parasitology 29, 777–780.CrossRefGoogle ScholarPubMed
Stear, M. J., Bishop, S. C., Doligalska, M., Duncan, J. L., Holmes, P. H., Irvine, J., McCririe, L., McKellar, Q. A., Sinski, E. and Murray, M. (1995). Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta. Parasite Immunology 17, 643–652.CrossRefGoogle ScholarPubMed
Strain, S. A. J., Bishop, S. C., Henderson, N. G., Kerr, A., McKellar, Q. A., Mitchell, S. and Stear, M. J. (2002). The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep. Parasitology 124, 545–552.CrossRefGoogle ScholarPubMed
Stien, A. S., Irvine, R. J., Langvatn, R., Albon, S. D. and Halvorsen, O. (2002). The population dynamics of Ostertagia gruehneri in reindeer: a model for the seasonal and intensity dependent variation in nematode fecundity. International Journal for Parasitology 32, 991–996.CrossRefGoogle Scholar
Tompkins, D. M. and Hudson, P. J. (1999). Regulation of nematode fecundity in the ring-necked pheasant (Phasianus clochicus): not just density dependence. Parasitology 118, 417–423.CrossRefGoogle Scholar
Viney, M. E. (2002). How do host immune responses affect nematode infections? Trends in Parasitology 18, 63–66.CrossRefGoogle ScholarPubMed
Viney, M. E., Steer, M. D. and Wilkes, C. P. (2006). The reversibility of constraints on size and fecundity in the parasitic nematode Strongyloides ratti. Parasitology 133, 477–483.CrossRefGoogle ScholarPubMed
Wilkes, C. P., Bleay, C., Paterson, S. and Viney, M. E. (2007). The immune response during a Strongyloides ratii infection of rats. Parasite Immunology 29, 339–346.CrossRefGoogle Scholar
Woolhouse, M. E. J. (1992). A theoretical framework for the immuno-epidemiology of helminth infection. Parasite Immunology 14, 563–578.CrossRefGoogle Scholar