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The distribution of Nippostrongylus brasiliensis in prolonged infections in lactating and neonatally infected rats

Published online by Cambridge University Press:  06 April 2009

R. M. Connan
R. M. Connan
Affiliation:
Department of Animal Pathology, Madingley Road, Cambridge
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Extract

In lactating rats examined 3 weeks post infection, adult Nippostrongylus brasiliensis were found in the duodenum close to the pylorus. Worms migrated from the predilection site, shown by Brambell (1965) and Alphey (1970) to be approximately 25% down the intestine, during the second week of infection. A similar migration took place in neonatally infected rats.

It was suggested that the migration was an active response to immunological damage. It could be prevented by early betamethasone treatment but only modified by treatment given late in infection.

Type
Research Article
Information
Parasitology , Volume 68 , Issue 3 , June 1974 , pp. 347 - 354
Copyright
Copyright © Cambridge University Press 1974

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References

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