Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-18T00:01:18.108Z Has data issue: false hasContentIssue false
  • English
  • Français

Plasmodium vivax: gametocyte infectivity of naturally infected Thai adults

Published online by Cambridge University Press:  06 April 2009

Jetsumon Sattabongkot ,
Nongnuj Maneechai  and
Ronald Rosenberg
Jetsumon Sattabongkot
Affiliation:
Department of Entomology, US Army Medical Component, 315/6 Rajavithi Road, Bangkok 10400, Thailand
Nongnuj Maneechai
Affiliation:
Department of Entomology, US Army Medical Component, 315/6 Rajavithi Road, Bangkok 10400, Thailand
Ronald Rosenberg
Affiliation:
Department of Entomology, US Army Medical Component, 315/6 Rajavithi Road, Bangkok 10400, Thailand
Get access Rights & Permissions [Opens in a new window]

Summary

Up to 200 laboratory reared Anopheles dirus mosquitoes were fed on each of 496 symptomatic Thai men who had patent, naturally acquired Plasmodium vivax gametocytaemia. Mean gametocyte densities were 455/mm3 (range: 0–3281), geometric mean oocyst number was 9 (0–142), mean frequency of infection was 43% (0–100%), and mean sporozoite number in salivary glands was 9525 (0–285 000). There was little relation between gametocyte density and either oocyst number or frequency of mosquito infection. There were, however, statistically strong positive correlations between oocyst numbers and frequency of infection, and between number of oocysts and number of salivary gland sporozoites. The data suggest that each oocyst contributed about 850 sporozoites to a gland infection.

Keywords

Plasmodium vivaxmalariagametocytesThailand
Type
Research Article
Information
Parasitology , Volume 102 , Issue 1 , February 1991 , pp. 27 - 31
Copyright
Copyright © Cambridge University Press 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Burkot, T. R., Graves, P. M., Cattani, J. A., Wirtz, R. A. & Gibson, F. D. (1987). The efficiency of sporozoite transmission in the human malarias, Plasmodium falciparum and P. vivax. Bulletin of the World Health Organization 65, 375–80.Google ScholarPubMed
Eyles, D. E. (1950). A stain for malarial oocysts in temporary preparations. Journal of Parasitology 36, 501.CrossRefGoogle ScholarPubMed
Eyles, D. E., Young, M. D. & Burgess, R. W. (1948). Studies on imported malarias 8. Infectivity to Anopheles quadrimaculatus of asymptomatic Plasmodium vivax parasitemias. Journal of the National Malaria Society 2, 125–33.Google Scholar
Graves, P. M., Burkot, T. R., Carter, R., Cattani, J. A., Lagog, M., Parker, J., Brabin, B. J., Gibson, F. D., Bradley, D. J. & Alpers, M. P. (1988). Measurement of malarial infectivity of human populations to mosquitoes in the Madang area, Papua New Guinea. Parasitology 96, 251–63.Google Scholar
Graves, P. M., Carter, R., Burkot, T. R., Quakyi, I. A. & Kumar, N. (1988). Antibodies to Plasmodium falciparum gamete surface antigens in Papua New Guinea sera. Parasite Immunology 10, 209–18.CrossRefGoogle ScholarPubMed
Hawking, F., Wilson, M. E. & Gammage, K. (1971). Evidence for cyclic development and short-lived maturity in the gametocytes of Plasmodium falciparum. Transactions of the Royal Society of Tropical Medicine 65, 549–59.CrossRefGoogle ScholarPubMed
Jeffery, G. M. & Eyles, D. E. (1955). Infectivity to mosquitoes of Plasmodium falciparum as related to gametocyte density and duration of infection. American Journal of Tropical Medicine and Hygiene 4, 781–9.Google Scholar
Jeffery, G. M. (1952). The infection of mosquitoes by Plasmodium vivax (Chesson strain) during the early primary parasitemias. American Journal of Tropical Medicine and Hygiene 1, 612–17.Google Scholar
Mendis, K. N., Munesinghe, Y. D., De Silva, Y. N. Y., Keragalla, I. & Carter, R. (1987). Malaria transmission-blocking immunity induced by natural infections of Plasmodium vivax in humans. Infection and Immunity 55, 369–72.Google Scholar
Munderloh, U. G. & Kurtti, T. (1987). The infectivity and purification of cultured Plasmodium berghei ookinetes. Journal of Parasitology 73, 919–23.CrossRefGoogle ScholarPubMed
Peiris, J. S. M., Premawansa, S., Ranawaka, M. B. R., Udagama, P. V., Munasinghe, Y. D., Nanayakkara, M. V., Gamage, C. P., Carter, R., David, P. H. & Mendis, K. N. (1988). Monoclonal and polyclonal antibodies both block and enhance transmission of human Plasmodium vivax malaria. American Journal of Tropical Medicine and Hygiene 39, 26–32.Google Scholar
Pringle, G. (1966). A quantitative study of naturally-acquired malaria infections in Anopheles gambiae and Anopheles funestus in a highly malarious area of East Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene 60, 626–32.Google Scholar
Rosenberg, R., Koontz, L. C., Alston, K. & Friedman, F. K. (1984). Plasmodium gallinaceum: erythrocyte factor essential for zygote infection of Aedes aegypti. Experimental Parasitology 57, 158–64.Google Scholar
Rosenberg, R., Koontz, L. C. & Carter, R. (1982). Infection of Aedes aegypti with zygotes of Plasmodium gallinaceum fertilized in vitro. Journal of Parasitology 68, 653–6.CrossRefGoogle ScholarPubMed
Rosenberg, R., Wirtz, R., Lanar, D., Sattabongkot, J., Hall, T., Walters, A. & Prasittisuk, C. (1989). Circumsporozoite protein heterogeneity in the human malaria parasite Plasmodium vivax. Science 245, 973–6.CrossRefGoogle ScholarPubMed
Rutledge, L. C., Hayes, D. E. & Ward, R. A. (1970). Plasmodium cynomolgi: Source of variation in susceptibility of Anopheles quadrimaculatus, A. balabacensis, and A. stephensi. Experimental Parasitology 27, 53–9.CrossRefGoogle ScholarPubMed
Rutledge, L. C., Ward, R. A. & Hayes, D. E. (1973). Plasmodium cynomolgi: the comparative infectiousness of individual rhesus monkeys. Experimental Parasitology 33, 126.Google Scholar
Ward, R. A. (1963). Genetic aspects of the susceptibility of mosquitoes to malarial infection. Experimental Parasitology 13, 328–41.Google Scholar
Wirtz, R. A., Burkot, T. R., Graves, P. M. & Andre, R. A. (1987). Field evaluation of enzyme-linked immunosorbent assays for Plasmodium falciparum and Plasmodium vivax sporozoites in mosquitoes (Diptera: Culicidae) from Papua New Guinea. Journal of Medical Entomology 24, 433–7.CrossRefGoogle ScholarPubMed
Young, M. D., Hardman, N. F., Burgess, R. W., Frohne, W. C. & Sabrosky, C. W. (1948). The infectivity of native malarias in South Carolina to Anopheles quadrimaculatus. American Journal of Tropical Medicine and Hygiene 28, 303–11.CrossRefGoogle ScholarPubMed