Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-28T16:05:50.178Z Has data issue: false hasContentIssue false
  • English
  • Français

Extra-hepatopulmonary cystic echinococcosis in Bulgaria: frequency, management and outcome of the disease

Published online by Cambridge University Press:  20 November 2020

Rumen N. Harizanov Open the ORCID record for Rumen N. Harizanov [Opens in a new window] ,
Iskra G. Rainova  and
Iskren T. Kaftandjiev
Rumen N. Harizanov*
Affiliation:
Department of Parasitology and Tropical Medicine, National Centre of Infectious and Parasitic Diseases, 26 Yanko Sakazov Blvd., 1504Sofia, Bulgaria
Iskra G. Rainova
Affiliation:
Department of Parasitology and Tropical Medicine, National Centre of Infectious and Parasitic Diseases, 26 Yanko Sakazov Blvd., 1504Sofia, Bulgaria
Iskren T. Kaftandjiev
Affiliation:
Department of Parasitology and Tropical Medicine, National Centre of Infectious and Parasitic Diseases, 26 Yanko Sakazov Blvd., 1504Sofia, Bulgaria
*
Author for correspondence: Rumen N. Harizanov, E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

In the endemic countries, human cystic echinococcosis (CE) poses a serious medical and social problem. Because it most often affects the liver and lungs we aimed to define the proportion of cases with different organ localization, the diagnostic and therapeutic approaches in such cases, and the outcome of them. For a period 2010–2019, a total of 2863 cases of CE were registered in Bulgaria, of which 148 (5.17%) with organ localization other than liver and/or lung. The majority of patients with extra-hepatopulmonary localization of CE were adults. The distribution by gender showed predominance of female patients (57.43%) over those of males and primary cases (85.14%) exceeded the cases of recurrence. According to our study most common is the spleen involvement, followed by involvement of the abdominal cavity, kidneys and muscle/subcutaneous tissue. Other extra-hepatopulmonary organ localizations are significantly less common. This study shows that the extra-hepatopulmonary localization of CE is not so rare, and in most cases it is a primary disease. In respect of this, clinicians should consider hydatidosis in the differential diagnosis when cystic formation(s) is found, regardless of the organ involved.

Keywords

Cystic echinococcosisdiagnosisextra-hepatopulmonary localizationoutcome
Type
Research Article
Information
Parasitology , Volume 148 , Issue 5 , April 2021 , pp. 562 - 565
Check for updates
Copyright
Copyright © The Author(s) 2021. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmadi, NA and Hamidi, M (2010) Unusual localizations of human hydatid disease in Hamedan province, west of Iran. Helminthologia 47, 94–98.CrossRefGoogle Scholar
Akbulut, S, Sogutcu, N and Eris, C (2013) Hydatid disease of the spleen: single-center experience and a brief literature review. Journal of Gastrointestinal Surgery 17, 1784–1795.CrossRefGoogle Scholar
Akbulut, S, Yavuz, R, Sogutcu, N, Kaya, B, Hatipoglu, S, Senol, A and Demircan, F (2014) Hydatid cyst of the pancreas: report of an undiagnosed case of pancreatic hydatid cyst and brief literature review. World Journal of Gastrointestinal Surgery 6, 190–200.CrossRefGoogle ScholarPubMed
Akcam, AT, Ulku, A, Koltas, IS, Izol, V, Bicer, OS, Kilicbagir, E, Sakman, G, Poyrazoglu, H, Erman, T, Aridogan, IA, Parsak, CK, Inal, M and Iskiti, S (2014) Clinical characterization of unusual cystic echinococcosis in southern part of Turkey. Annals of Saudi Medicine 34, 508–516.CrossRefGoogle ScholarPubMed
Altinörs, N, Bavbek, M, Caner, HH and Erdogan, B (2000) Central nervous system hydatidosis in Turkey: a cooperative study and literature survey analysis of 458 cases. Journal of Neurosurgery 93, 1–8.CrossRefGoogle ScholarPubMed
Bartın, MK (2019) Hydatid cyst disease with extra hepatic localizations. Biomedical Journal of Scientific & Technical Research 19, 14625–14628. doi: 10.26717/BJSTR.2019.19.003367Google Scholar
Belli, S, Akbulut, S, Erbay, G and Koçer, NE (2014) Spontaneous giant splenic hydatid cyst rupture causing fatal anaphylactic shock: a case report and brief literature review. Turkish Journal of Gastroenterology 25, 88–91.CrossRefGoogle ScholarPubMed
Burgazli, KM, Ozdemir, CS, Beken Ozdemir, E, Mericliler, M and Polat, ZP (2013) Unusual localization of a primary hydatid cyst: a subcutaneous mass in the paraumbilical region. European Review for Medical and Pharmacological Sciences 17, 1766–1768.Google ScholarPubMed
Çakır, M, Balasar, M, Küçükkartallar, T, et al. (2016) Management of extra-hepatopulmonary hydatid cysts (157 cases). Turkiye Parazitolojii Dergisi 40, 72–76.CrossRefGoogle Scholar
Cöl, C, Cöl, M and Lafçi, H (2003) Unusual localizations of hydatid disease. Acta Medica Austriaca 30, 61–64.CrossRefGoogle ScholarPubMed
Eckert, J, Gemmell, MA, Meslin, F-X and Pawlowski, ZS and World Health Organization (2001) WHO/OIE Manual on Echinococcosis in Humans and Animals: A Public Health Problem of Global Concern. Paris, France: World Organisation for Animal Health.Google Scholar
Engin, G, Acunaş, B, Rozanes, I and Acunaş, G (2000) Hydatid disease with unusual localization. European Radiology 10, 1904–1912.CrossRefGoogle ScholarPubMed
Eris, C, Akbulut, S, Yildiz, MK, Abuoglu, H, Odabasi, M, Ozkan, E, Atalay, S and Gunay, E (2013) Surgical approach to splenic hydatid cyst: single center experience. International Surgery 98, 346–353.CrossRefGoogle ScholarPubMed
European Food Safety Authority & European Centre for Disease Prevention and Control (2018) The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017. EFSA Journal 16, 5500.Google Scholar
García-Alvarez, F, Torcal, J, Salinas, JC, et al. (2002) Musculoskeletal hydatid disease: a report of 13 cases. Acta Orthopaedica Scandinavica 73, 227–231.CrossRefGoogle ScholarPubMed
Harizanov, R, Rainova, I and Kaftandjiev, I (2019) Human cystic echinococcosis, trichinellosis, and toxocariasis in Bulgaria: an update of data for 2015–2017. International Medicine 1, 43–50.CrossRefGoogle Scholar
Ibn Elhadj, Z, Boukhris, M, Kammoun, I, Halima, AB, Addad, F and Kachboura, S (2014) Cardiac hydatid cyst revealed by ventricular tachycardia. Journal of the Saudi Heart Association 26, 47–50.CrossRefGoogle ScholarPubMed
Prousalidis, J, Tzardinoglou, K, Sgouradis, L, Katsohis, C and Aletras, H (1998) Uncommon sites of hydatid disease. World Journal of Surgery 22, 17–22.CrossRefGoogle ScholarPubMed
Sarkari, B and Rezaei, Z (2015) Immunodiagnosis of human hydatid disease: where do we stand? World Journal of Methodology 5, 185–195.CrossRefGoogle ScholarPubMed
World Health Organization (2020) Echinococcosis fact sheet. Retrieved from WHO website: https://www.who.int/news-room/fact-sheets/detail/echinococcosis (Accessed 29 June 2020).Google Scholar