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The anticoccidial effects of amprolium, dinitolmide and monensin against Eimeria maxima, E. brunetti and E. acervulina with particular reference to oocyst sporulation

Published online by Cambridge University Press:  06 April 2009

L. P. Joyner  and
C. C. Norton
L. P. Joyner
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
C. C. Norton
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
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Extract

Chicks infected with the Weybridge strains of Eimeria maxima and E. acervulina were not protected by the normal levels of amprolium, but the sporulation of the oocysts was inhibited. With higher drug concentrations, fewer oocysts were produced. E. brunetti was not so markedly affected, although oocyst sporulation was reduced by the higher dosage levels. The effects were not enhanced by the inclusion of ethopabate.

With dinitolmide the phenomenon was not so marked, although oocyats of E. maxima and E. acervulina were reduced in numbers by the normal drug concentration and sporulation was reduced when this level was increased. Much higher drug levels were required to obtain these effects with E. brunetti. Monensin at 120 ppm affected neither oocyst numbers nor their sporulation in any of the species tested. The significance of the effects of anticoccidial drugs on gametogony and sporogony is discussed.

Type
Research Article
Information
Parasitology , Volume 75 , Issue 2 , October 1977 , pp. 155 - 164
Copyright
Copyright © Cambridge University Press 1977

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References

Ajayi, J. A. (1976). Effects of Aureo-S-700n on sporulation, viability and infectivity of ovine coccidial oocysts. Parasitology 72, 335–43.CrossRefGoogle ScholarPubMed
Brackett, S. & Bliznick, A. (1949). The effect of small doses of drugs on oocyst production of infections with Eimeria tenella. Annals of the New York Academy of Sciences 52, 595–610.CrossRefGoogle Scholar
Chapman, H. D. (1976). Resistance of field isolates of Eimeria species to anticoccidial drugs. Avian Pathology 5, 283–90.CrossRefGoogle ScholarPubMed
Davies, S. F. M. & Joyner, L. P. (1963). Design of therapy for the control of species of Eimeria in the domestic fowl. Journal of Comparative Pathology and Therapeutics 73, 379–90.CrossRefGoogle ScholarPubMed
International Minerals Chemical Corporation (1973). 6-amino-9-benzyl purine derivatives. G. B. Patent Specification 1338520. 28 November 1973.Google Scholar
Joyner, L. P. & Norton, C. C. (1971). The recording and analysis of coccidiostatic activity; quinolone and pyridone compounds. Research in Veterinary Science 12, 80–8.CrossRefGoogle ScholarPubMed
Kogan, S. M. (1960). Effect of sulfamides administered to chicks on the capacity to sporulation in the oocysts of Eimeria necatrix. Zoologischeski Zhurnal 39, 978–83.Google Scholar
Long, P. L. (1972). Observations on the oocyst production and viability of Eimeria mivati and E. tenella in the chorioallantois of chicken embryos incubated at different temperatures. Zeitschrift für Parasitenkunde 39, 27–37.CrossRefGoogle Scholar
Long, P. L. & Rowell, J. G. (1958). Counting oocysts of chicken coccidia. Laboratory Practice 7, 515–18.Google Scholar
Long, P. L., Tompkins, R. V. & Millard, B. J. (1975). Coccidiosis in broilers; evaluation of infection by the examination of broiler house litter for oocysts. Avian Pathology 4, 287–94.CrossRefGoogle ScholarPubMed
Mcmanus, E. G., Oberdick, M. T. & Cuckler, A. C. (1967). Response of six strains of Eimeria brunetti to two antagonists of para-aminobenzoic acid. Journal of Pretozoology 14, 379–81.CrossRefGoogle ScholarPubMed
Norton, C. C. & Joyner, L. P. (1975). The development of drug-resistant strains of Eimeria maxima in the laboratory. . Parasitology 71, 153–65.CrossRefGoogle ScholarPubMed
Reid, W. M. (1969). Efficacy studies on some new anticoccidial drugs. Acta Veterinaria (Brno) 38, 137–45.Google Scholar
Reid, W. M. (1975). Relative value of oocyst counts in evaluating anticoccidial activity. Avian Diseases 19, 802–11.CrossRefGoogle ScholarPubMed
Ryley, J. F. (1967). Methyl benzoquate, a new wide-spectrum coccidiostat for chickens. British Veterinary Journal 123, 513–20.CrossRefGoogle ScholarPubMed
Ryley, J. F. & Betts, M. J. (1973). Chemotherapy of chicken coccidiosis. In Advances in Pharmacology and Chemotherapy, vol. 11, pp. 221–89. New York: Academic Press.Google Scholar