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The Influence of Legume Seeds on Human Plasma Lipid Concentrations

Published online by Cambridge University Press:  14 December 2007

Susan M. Kingman
Susan M. Kingman
Affiliation:
Dunn Clinical Nutrition Centre, 100 Tennis Court Road, Cambridge CB2 1QL
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Type
Research Article
Information
Nutrition Research Reviews , Volume 4 , Issue 1 , January 1991 , pp. 97 - 123
Copyright
Copyright © The Nutrition Society 1991

References

REFERENCES

Anderson, D. W., Nichols, A. V., Pan, S. S. & Lindgren, F. T. (1978). High density lipoprotein distribution. Resolution and determination of three major components in a normal population sample. Atherosclerosis 29, 161–179.CrossRefGoogle Scholar
Anderson, J. W., Gustafson, N. J., Spencer, D. B., Tietyen, J. & Bryant, C. A. (1990). Serum lipid response of hypercholesterolemic men to single and divided doses of canned beans. American Journal of Clinical Nutrition 51, 1013–1019.CrossRefGoogle ScholarPubMed
Anderson, J. W., Story, L., Sieling, B. & Chen, W.-J. L. (1984 a). Hypocholesterolaemic effects of high-fibre diets rich in water-soluble plant fibres. Journal of the Canadian Dietetic Association 45, 140–148.Google Scholar
Anderson, J. W., Story, L., Sieling, B., Chen, W.-J. L., Petro, M. S. & Story, J. (1984 b). Hypocholesterolaemic effects of oat bran or bean intake for hypercholesterolaemic men. American Journal of Clinical Nutrition 40, 1146–1155.CrossRefGoogle Scholar
Aro, A., Uusitupa, M., Voutilainen, E., Hersio, K., Korhonen, T. & Siitonen, O. (1981). Improved diabetic control and hypocholesterolaemic effect induced by long-term dietary supplementation with guar gum in type 2 (insulin-independent) diabetes. Diabetalogia 21, 29–33.CrossRefGoogle ScholarPubMed
Aro, A., Uusitupa, M., Voutilainen, E. & Korthonen, T. (1984). Effects of guar gum in male subjects with hypercholesterolemia. American Journal of Clinical Nutrition 39, 911–916.CrossRefGoogle ScholarPubMed
Beynen, A. C., Katan, M. B. & Van Zutphen, L. F. M. (1987). Hypo- and hyper-responders: individual differences in the response of serum cholesterol concentrations to changes in diet. Advances in Lipid Research 22, 115–171.CrossRefGoogle Scholar
Bingwen, L., Zhaofeng, W., Wanzhen, L. & Rongjue, Z. (1981). Effects of bean meal on serum cholesterol and triglycerides. Chinese Medical Journal 94, 455–458.Google Scholar
Blackburn, N. A., Redfern, J. S., Jarjis, H., Holgate, A. M., Hanning, I., Scarpello, J. H. B., Johnson, I. T. & Read, N. W. (1984). The mechanism of action of guar gum in improving glucose tolerance in man. Clinical Science 66, 329–336.CrossRefGoogle ScholarPubMed
Brown, M. S. & Goldstein, J. L. (1976). Receptor mediated control of cholesterol metabolism. Science 191, 150–154.CrossRefGoogle ScholarPubMed
Brown, M. S. & Goldstein, J. L. (1983). Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic. Journal of Clinical Investigation 72, 743–747.CrossRefGoogle ScholarPubMed
Bush, R. S. & Milligan, L. P. (1971). Study of the mechanism of inhibition of ketogenesis by propionate in bovine liver. Canadian Journal of Animal Science 51, 121–127.CrossRefGoogle Scholar
Calvert, G. D., Blight, L., Illman, R. J., Topping, D. L. & Potter, J. D. (1981). A trial of the effects of soya-bean flour and soya-bean saponins on plasma lipids, faecal bile acids and neutral sterols in hypercholesterolaemic men. British Journal of Nutrition 45, 277–281.CrossRefGoogle ScholarPubMed
Carroll, K. K., Giovannetti, P. M., Huff, M. W., Moase, O., Roberts, D. C. K. & Wolfe, B. M. (1978). Hypocholesterolaemic effect of substituting soybean protein for animal protein in the diet of healthy young women. American Journal of Clinical Nutrition 31, 1312–1321.CrossRefGoogle Scholar
Champ, M., Brillouet, J.-M. & Rouau, X. (1986). Nonstarchy polysaccharides of Phaseolus vulgaris, Lens esculenta, and Cicer arietinum seeds. Journal of Agricultural and Food Chemistry 34, 326–329.CrossRefGoogle Scholar
Chen, W. L., Anderson, J. W. & Jennings, D. (1984). Propionate may mediate the hypocholesterolemic effect of certain soluble plant fibers in cholesterol-fed rats. Proceedings of the Society for Experimental Biology and Medicine 175, 215–218.CrossRefGoogle ScholarPubMed
Cobiac, L., McArthur, R. & Nestel, P. J. (1990). Can eating baked beans lower plasma cholesterol? European Journal of Clinical Nutrition 44, 819–822.Google ScholarPubMed
Connor, W. E. & Connor, S. L. (1972). The key role of nutritional factors in the prevention of coronary heart disease. Preventive Medicine 1, 49–83.CrossRefGoogle ScholarPubMed
Cortese, C., Levy, Y., Janus, E. D., Turner, P. R., Rao, S. N., Miller, N. E. & Lewis, B. (1983). Modes of action of lipid lowering diets in man: studies of apolipoprotein B kinetics in relation to fat consumption and dietary fatty acid composition. European Journal of Clinical Investigation 13, 79–85.CrossRefGoogle ScholarPubMed
Covarrubias, C., Valdivieso, V. & Nervi, F. (1984). Epidemiology of gallstone disease in Chile. In Epidemiology and Prevention of Gallstone Disease, pp. 26–30. [Capocaccia, L., Ricci, G., Angelico, M. and Attili, A. F., editors]. Lancaster: MTP Press.CrossRefGoogle Scholar
Descovich, G. C., Gaddi, A., Mannino, G., Cattin, L., Senin, U., Caruzzo, C., Fragiacomo, C., Sirtori, M., Ceredi, C., Benassi, M. S., Colombo, L., Fontana, G., Mannarino, E., Bertelli, E., Noseda, G. & Sirtori, C. R. (1980). Multicentre study of soybean protein diet for outpatient hypercholesterolaemic patients. Lancet ii, 709–712.CrossRefGoogle Scholar
Dietschy, J. M. (1984). Regulation of cholesterol metabolism in man and other species. Klinische Wohenschrift 62, 338–345.CrossRefGoogle ScholarPubMed
Dietschy, J. M. & Siperstein, M. D. (1967). Effect of cholesterol feeding and fasting on sterol synthesis in seventeen tissues in the rat. Journal of Lipid Research 8, 97–104.CrossRefGoogle ScholarPubMed
Dietschy, J. M. & Wilson, J. D. (1970). Regulation of cholesterol metabolism. New England Journal of Medicine 282, 1128–1138.CrossRefGoogle ScholarPubMed
Duke, J. A. (1981). Handbook of Legumes of World Economic Importance. New York: Plenum Press.CrossRefGoogle Scholar
Eisenberg, S. (1984). High density lipoprotein metabolism. Journal of Lipid Research 25, 1017–1058.CrossRefGoogle ScholarPubMed
Eisenberg, S. & Levy, R. I. (1975). Lipoprotein metabolism. Advances in Lipid Research 13, 1–89.CrossRefGoogle ScholarPubMed
Englyst, H. N., Bingham, S. A., Runswick, S. A., Collinson, E. & Cummings, J. H. (1988). Dietary fibre (non-starch polysaccharides) in fruit, vegetables and nuts. Journal of Human Nutrition 1, 247–286.Google Scholar
Englyst, H. N., Hay, S. & Macfarlane, G. T. (1987). Polysaccharide breakdown by mixed populations of human faecal bacteria. FEMS Microbiology Ecology 45, 163–171.CrossRefGoogle Scholar
Englyst, H. N. & Kingman, S. M. (1990). Dietary fiber and resistant starch. A nutritional classification of plant polysaccharides. In Dietary Fiber, pp. 49–65. [Kritchevsky, D., Bonfield, C. and Anderson, J. W., editors]. New York: Plenum Press.CrossRefGoogle ScholarPubMed
Fredrickson, D. S., Levy, R. I. & Lees, R. S. (1967). Fat transport in lipoproteins–an integrated approach to mechanisms and disorders. New England Journal of Medicine 276, 34–44.CrossRefGoogle ScholarPubMed
Fumagalli, R., Soleri, L., Farina, R., Musanti, R., Mantero, O., Noseda, G. & Gatti, E. (1982). Faecal cholesterol excretion studies in type II hypercholesterolaemic patients treated with soyabean protein diet. Atherosclerosis 43, 341–353.CrossRefGoogle ScholarPubMed
Gatti, E., Catenazzo, G., Camisasca, E., Torri, A., Denegri, E. & Sirtori, C. R. (1984). Effects of guar-enriched pasta in the treatment of diabetes and hyperlipidaemia. Annals of Nutrition and Metabolism 28, 1–10.CrossRefGoogle Scholar
Giovannetti, P. M., Carroll, K. K. & Wolfe, B. M. (1986). Constancy of fasting serum cholesterol of healthy young women upon substitution of soy protein isolate for meat and dairy protein in medium and low fat diets. Nutrition Research 6, 609–618.CrossRefGoogle Scholar
Goldberg, A. P., Lim, A., Kolar, J. B., Grundhauser, J. J., Steinke, F. H. & Schonfeld, G. (1982). Soybean protein independently lowers plasma cholesterol levels in primary hypercholesterolaemia. Atherosclerosis 43, 355–368.CrossRefGoogle Scholar
Goldstein, J. L. & Brown, M. S. (1977). The low density lipoprotein pathway and its relation to atherosclerosis. Annual Review of Biochemistry 46, 897–930.CrossRefGoogle ScholarPubMed
Goldstein, J. L. & Brown, M. S. (1984). Progress in Understanding the LDL receptor and HMG CoA reductase: two membrane proteins that regulate the plasma cholesteol. Journal of Lipid Research 25, 1450–1461.CrossRefGoogle Scholar
Goodlad, J. S. & Mathers, J. C. (1988). Effects of food carbohydrates on large intestinal fermentation in vitro. Proceedings of the Nutrition Society 47, 176A.Google Scholar
Gordon, D. J. & Rifkind, B. M. (1987). 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG CoA) reductase inhibitors: a new class of cholesterol-lowering agents. Annals of Internal Medicine 107, 759–761.CrossRefGoogle Scholar
Grande, F., Anderson, J. T. & Keys, A. (1965). Effect of carbohydrates of leguminous seeds, wheat and potatoes on serum cholesterol concentration in man. Journal of Nutrition 86, 313–318.CrossRefGoogle ScholarPubMed
Grande, F., Anderson, J. T. & Keys, A. (1974). Sucrose and various carbohydrate-containing foods and serum lipids in man. American Journal of Clinical Nutrition 27, 1043–1051.CrossRefGoogle ScholarPubMed
Grundy, S. M. (1978). Cholesterol metabolism in man. Western Journal of Medicine 128, 13–25.Google ScholarPubMed
Grundy, S. M. (1983). Absorption and metabolism of dietary cholesterol. Annual Review of Nutrition 3, 71–96.CrossRefGoogle ScholarPubMed
Grundy, S. M. (1987). Dietary therapy of hyperlipidaemia. In Baillière's Clinical Endocrinology and Metabolism. International Practice and Research. Lipoprotein Metabolism vol. 1, pp. 667–698 [Shepherd, J., editor]. London: Baillière Tindall.Google Scholar
Grundy, S. M. & Abrams, J. J. (1983). Comparison of actions of soy protein and casein on metabolism of plasma lipoproteins and cholesterol in humans. American Journal of Clinical Nutrition 38, 245–252.CrossRefGoogle ScholarPubMed
Grundy, S. M. & Metzger, A. L. (1972). A physiological method for estimation of hepatic secretion of biliary lipids in man. Gastroenterology 62, 1200–1217.CrossRefGoogle ScholarPubMed
Hofmann, A. F. & Borgstrom, B. (1962). Physico-chemical state of lipids in intestinal content during their digestion and absorption. Federation Proceedings 21, 43–50.Google ScholarPubMed
Hofmann, A. F. & Borgstrom, B. (1964). The intraluminal phase of fat digestion in man: the lipid content of the micellar and oil phases of intestinal content obtained during fat digestion and absorption. Journal of Clinical Investigation 43, 247–257.CrossRefGoogle ScholarPubMed
Holmes, W. L., Rubel, G. B. & Hood, S. S. (1980). Comparison of the effect of dietary meat versus dietary soybean protein on plasma lipids of hyperlipidaemic individuals. Atherosclerosis 36, 379–387.CrossRefGoogle Scholar
Huff, M. W., Giovannetti, P. M. & Wolfe, B. M. (1984). Turnover of very low-density lipoprotein-apoprotein B is increased by substitution of soybean protein for meat and dairy protein in the diets of hypercholesterolemic men. American Journal of Clinical Nutrition 39, 888–897.CrossRefGoogle ScholarPubMed
Huttunen, J. K., Enholm, C., Kekki, M. & Nikkila, E. A. (1976). Post-heparin plasma lipoprotein lipase and hepatic lipase in normal subjects and in patients with hypertriglyceridaemia: correlations to sex, age and various parameters of triglyceride metabolism. Clinical Science and Molecular Medicine 50, 249–260.Google ScholarPubMed
Imaizumi, K., Fainaru, M. & Havel, R. J. (1978). Composition of proteins of mesenteric lymph chylomicrons in the rat and alterations produced upon exposure of chylomicrons to blood serum and serum proteins. Journal of Lipid Research 19, 712–722.CrossRefGoogle ScholarPubMed
Innerarity, T. L., Hui, D. Y. & Mahley, R. W. (1982). Hepatic apoprotein E (remnant) receptors. In Lipoproteins and Coronary Atherosclerosis, pp. 173–182 [Noseda, G., Fragiacomo, C., Fumagalli, R. and Paoletti, R., editors]. Amsterdam: Elsevier Biomedical Press.Google Scholar
Janus, E. D., Nicoll, A. M., Wootton, R., Turner, P. R., Magill, P. J. & Lewis, B. (1980). Quantitative studies of very low density lipoprotein conversion to low density lipoprotein in normal controls and primary hyperlipidaemic states and the role of direct secretion of low density lipoprotein in heterozygous familial hypercholesteolaemia. European Journal of Clinical Investigation 10, 149–159.CrossRefGoogle Scholar
Jenkins, D. J. A. & Jepson, E. M. (1982). Leguminous seeds and their constituents in the treatment of hyperlipidaemia and diabetes. In Lipoproteins and Coronary Atherosclerosis, pp. 247–256. [Noseda, G., Fragiacomo, C., Fumagalli, R. and Paoletti, R. editors]. Amsterdam: Elsevier Biomedical Press.Google Scholar
Jenkins, D. J. A., Leeds, A. R., Gassull, M. A., Houston, H., Goff, D. V. & Hill, M. J. (1976 a). The cholesterol lowering properties of guar and pectin. Clinical Science and Molecular Medicine 51, 8p–9p.Google Scholar
Jenkins, D. J. A., Leeds, A. R., Slavin, B. & Jepson, E. M. (1976 b). Guar gum in hyperlipdaemia. Lancet ii, 1351.CrossRefGoogle Scholar
Jenkins, D. J. A., Newton, C., Leeds, A. R. & Cummings, J. H. (1975). Effect of pectin, guar gum and wheat fibre on serum cholesterol. Lancet i, 1116–1117.CrossRefGoogle Scholar
Jenkins, D. J. A., Reynolds, D., Leeds, A. R., Waller, A. L. & Cummings, J. H. (1979). Hypocholesterolaemic action of dietary fiber unrelated to faecal bulking effect. American Journal of Clinical Nutrition 32, 2430–2435.CrossRefGoogle ScholarPubMed
Jenkins, D. J. A., Reynolds, D., Slavin, B., Leeds, A. R., Jenkins, A. L. & Jepson, E. M. (1980 a). Dietary fiber and blood lipids: treatment of hypercholesterolemia with guar crispbread. American Journal of Clinical Nutrition 33, 575–581.CrossRefGoogle ScholarPubMed
Jenkins, D. J. A., Wolever, T. M. S., Kalmusky, J., Guidici, S., Giordano, C., Patten, R., Wong, G. S., Bird, J. N., Hall, M., Buckley, G., Csima, A. & Little, J. A. (1987). Low glycemic index diet in hyperlipidemia: use of traditional starchy foods. American Journal of Clinical Nutrition 46, 66–71.CrossRefGoogle ScholarPubMed
Jenkins, D. J. A., Wolever, T. M. S., Ocana, A. M., Vuksan, V., Cunnane, S. C., Jenkins, M., Wong, G. S., Singer, W., Bloom, S. R., Blendis, L. M. & Josse, R. G. (1990). Metabolic effects of reducing rate of glucose ingestion by single bolus versus continuous sipping. Diabetes 39, 775–781.CrossRefGoogle ScholarPubMed
Jenkins, D. J. A., Wolever, T. M. S., Taylor, R. H., Barker, H. M. & Fielden, H. (1980 b). Exceptionally low blood glucose response to dried beans: comparison with other carbohydrate foods. British Medical Journal 281, 578–580.CrossRefGoogle ScholarPubMed
Jenkins, D. J. A., Wolever, T. M. S., Vuksan, V., Brighenti, F., Cunnane, S., Rao, A. V., Buckley, G., Patten, R., Singer, W. & Josse, R. G. (1989). Nibbling versus gorging: metabolic advantages of increased meal frequency. New England Journal of Medicine 321, 929–934.CrossRefGoogle ScholarPubMed
Jenkins, D. J. A., Wong, G. S., Patten, R., Bird, J., Hall, M., Buckley, G. C., McGuire, V., Reichert, R. & Little, J. A. (1983). Leguminous seeds in the dietary management of hyperlipidemia. American Journal of Clinical Nutrition 38, 567–573.CrossRefGoogle ScholarPubMed
Kanamori, M., Ikeuchi, T., Ibuki, F., Kotaru, M. & Kan, K. K. (1982). Amino acid composition of protein fractions extracted from Phaseolus beans and the field bean (Vicia faba L.). Journal of Food Science 47, 1991–1994.CrossRefGoogle Scholar
Kekki, M. (1980). Lipoprotein lipase action determining plasma high density lipoprotein cholesterol level in adult normolipaemics. Atherosclerosis 37, 143–150.CrossRefGoogle ScholarPubMed
Khan, A. R., Khan, G. Y., Mitchel, A. & Qadeer, M. A. (1981). Effect of guar gum on blood lipids. American Journal of Clinical Nutrition 34, 2446–2449.CrossRefGoogle ScholarPubMed
Kingman, S. M., Low, A. G., Sambrook, I. E., Owen, R. W. & Walker, A. F. (1992). Comparative effect of four legume species on plasma lipids and faecal steroid excretion in hypercholesterolaemic pigs. British Journal of Nutrition (In the Press).Google Scholar
Lakshmanan, M. R., Nepokroeff, C. M., Ness, G. C., Dugan, R. E. & Porter, J. W. (1973). Stimulation by insulin of rat liver β-hydroxy β-methylglutaryl coenzyme A reductase and cholesterol synthesising activities. Biochemical and Biophysical Research Communications 50, 704–710.CrossRefGoogle Scholar
Levy, R. I. (1981). Review: cholesterol, lipoproteins, apoproteins and heart disease: present status and future prospects. Clinical Chemistry 27, 653–662.CrossRefGoogle Scholar
Lo, G. S., Goldberg, A. P., Lim, A., Grundhauser, J. J., Anderson, C. & Schonfeld, G. (1986). Soy fiber improves lipid and carbohydrate metabolism in primary hyperlipidaemic subjects. Atherosclerosis 62, 239–248.CrossRefGoogle Scholar
Lovati, M. R., Manzoni, C., Canavesi, A., Sirtori, M., Vaccarino, V., Marchi, M., Gaddi, G. & Sirtori, C. R. (1987). Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells from hypercholesterolaemic patients. Journal of Clinical Investigation 80, 1498–1502.CrossRefGoogle Scholar
Lovati, M. R., West, C. E., Sirtori, C. R. & Beynen, A. C. (1990). Dietary animal proteins and cholesterol metabolism in rabbits. British Journal of Nutrition 64, 473–485.CrossRefGoogle ScholarPubMed
Luyken, R., Pikaar, N. A., Polman, H. & Schippers, F. (1962). The influence of legumes on the serum cholesterol level. Voeding 23, 447–453.Google ScholarPubMed
Ma, P. T. S., Gil, G., Sudhof, T. C., Bilheimer, D. W., Goldstein, J. L. & Brown, M. S. (1986). Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in the liver of hamsters and rabbits. Proceedings of the National Academy of Sciences U.S.A. 83, 8370–8374.CrossRefGoogle ScholarPubMed
McIvor, M. E., Cummings, C. C., Van Duyn, M. A., Leo, T. A., Margolis, S., Behall, K. M., Michnowski, J. A. & Mendeloff, A. I. (1986). Long term effects of guar gum on blood lipids. Atherosclerosis 60, 7–13.CrossRefGoogle ScholarPubMed
Malinow, M. R. (1984). Saponins and cholesterol metabolism. Atherosclerosis 50, 117–119.CrossRefGoogle ScholarPubMed
Malinow, M. R., Connor, W. E., McLaughlin, P., Stafford, C., Lin, D. S., Livingston, A. L., Kohler, G. O. & McNulty, W. P. (1981). Cholesterol and bile acid balance in Macaca fascicularis. Effects of alfalfa saponins. Journal of Clinical Investigation 67, 156–162.CrossRefGoogle ScholarPubMed
Mathur, K. S., Khan, M. A. & Sharma, R. D. (1968). Hypocholesterolaemic effect of Bengal gram: a long-term study in man. British Medical Journal 1, 30–31.CrossRefGoogle Scholar
Mayes, P. A. & Topping, D. L. (1974). Regulation of hepatic lipogenesis by plasma-free fatty acids: simultaneous studies on lipoprotein secretion, cholesterol synthesis, ketogenesis and gluconeogenesis. Biochemical Journal 140, 111–114.CrossRefGoogle ScholarPubMed
Meinertz, H., Faergeman, O., Nilausen, K., Chapman, M. J., Goldstein, S. & Laplaud, P. M. (1988). Effects of soy protein and casein in low cholesterol diets on plasma lipoproteins in normolipidaemic subjects. Atherosclerosis 72, 63–70.CrossRefGoogle Scholar
Meinertz, H., Nilausen, K. & Faergeman, O. (1989). Soy protein and casein in cholesterol-enriched diets: effects on plasma lipoproteins in normolipidemic subjects. American Journal of Clinical Nutrition 50, 786–793.CrossRefGoogle ScholarPubMed
Molgaard, J., von Schenck, H. & Olsson, A. G. (1987). Alfalfa seeds lower low density lipoprotein cholesterol and apolipoprotein B concentrations in patients with type II hyperlipoproteinaemia. Atherosclerosis 65, 173–179.CrossRefGoogle Scholar
Mosse, J. & Pernollet, J. C. (1983). Storage proteins of legume seeds. In Chemistry and Biochemistry of Legumes, pp. 111–193 [Akora, S. K. editor]. London: Edward Arnold.Google Scholar
Nervi, F., Covarrubias, C., Bravo, P., Velasco, N., Ulloa, N., Cruz, F., Fava, M., Severin, C., del Pozo, R., Antezana, C., Valdivieso, V. & Artega, A. (1989). Influence of legume intake on biliary lipids and cholesterol saturation in young Chilean men. Gastroenterology 96, 825–830.CrossRefGoogle ScholarPubMed
Noseda, G., Fragiacomo, C. & Cairoli, R. (1982). Hormonal effects of soybean protein diet versus casein rich diet. In Lipoproteins and Coronary Atherosclerosis, pp. 299–302. [Noseda, G., Fragiacomo, C., Fumagalli, R. and Paoletti, R., editors]. Amsterdam: Elsevier Biomedical Press.Google Scholar
O'Dea, K. & Wong, S. (1983). The rate of starch hydrolysis in vitro does not predict the metabolic responses to legumes in vivo. American Journal of Clinical Nutrition 38, 382–387.CrossRefGoogle Scholar
Packard, C. J., Munro, A., Lorimer, A. R., Gotto, A. M. & Shepherd, J. (1984). Metabolism of apolipoprotein B in large triglyceride rich very low density lipoproteins of normal and hypertriglyceridaemic subjects. Journal of Clinical Investigation 74, 2178–2192.CrossRefGoogle Scholar
Paul, A. A. & Southgate, D. A. T. (1978). McCance and Widdowson's The Composition of Foods, 4th ed. London: H. M. Stationery Office.Google Scholar
Penagini, R., Velio, P., Vigorelli, R., Bozzani, A., Castagnone, D., Ranzi, T. & Bianchi, P. A. (1986). The effect of dietary guar on serum cholesterol, intestinal transit and faecal output in man. American Journal of Gastroenterology 81, 123–125.Google ScholarPubMed
Price, K. R., Johnson, I. T. & Fenwick, G. R. (1987). The chemistry and biological significance of saponins in food and feeding stuffs. CRC Critical Reviews in Food Science and Nutrition 26, 27–135.CrossRefGoogle Scholar
Price, K. R., Lewis, J., Wyatt, G. M. & Fenwick, G. R. (1988). Flatulence – causes, relation to diet and remedies. Die Nahrung 32, 609–626.CrossRefGoogle ScholarPubMed
Reddy, N. R., Pierson, M. D., Sathe, S. K. & Salunkhe, D. K. (1984). Chemical, nutritional and physiological aspects of dry bean carbohydrates – a review. Food Chemistry 13, 25–68.CrossRefGoogle Scholar
Sabine, J. R. (1977). Cholesterol. New York: Marcel Dekker.Google Scholar
Sacks, F. M., Breslow, J. L., Wood, P. G. & Kass, E. H. (1983). Lack of effect of dairy protein (casein) and soy protein on plasma cholesterol in strict vegetarians. An experiment and a critical review. Journal of Lipid Research 24, 1012–1020.CrossRefGoogle ScholarPubMed
Salunkhe, D. K., Sathe, S. K. & Reddy, N. R. (1983). Legume lipids. In Chemistry and Biochemisty of Legumes, pp. 51–109 [Akora, S. K., editor]. London: Edward Arnold.Google Scholar
Sasaki, J., Funakoshi, M. & Arakawa, K. (1985). Effect of soybean crude fiber on the concentrations of serum lipids and apolipoproteins in hyperlipemic subjects. Annals of Nutrition and Metabolism 29, 274–278.CrossRefGoogle ScholarPubMed
Schaefer, E. J., Eisenberg, S. & Levy, R. I. (1978). Lipoprotein apoprotein metabolism. Journal of Lipid Research 19, 667–687.CrossRefGoogle ScholarPubMed
Schweizer, T. F., Bekhechi, A. R., Koellreutter, B., Reimann, S., Pometta, D. & Bron, B. A. (1983). Metabolic effects of dietary fiber from dehulled soybeans in humans. American Journal of Clinical Nutrition 38, 1–11.CrossRefGoogle ScholarPubMed
Sharma, R. D. & Raghuram, T. C. (1990). Hypoglycaemic effect of fenugreek seeds in non-insulin dependent diabetic subjects. Nutrition Research 10, 731–739.CrossRefGoogle Scholar
Shorey, R. L., Bazan, B., Lo, G. S. & Steinke, F. H. (1981). Determinants of hypocholesterolaemic response to soy and animal protein-based diets. American Journal of Clinical Nutrition 34, 1769–1778.CrossRefGoogle Scholar
Shorey, R. L., Day, P. J., Willis, R. A., Lo, G. S. & Steinke, F. H. (1985). Effects of soybean polysaccharide on plasma lipids. Journal of the American Dietetic Association 85, 1461–1465.CrossRefGoogle ScholarPubMed
Shutler, S. M. (1988). Investigations into the hypocholesterolaemic effect of legumes. PhD Thesis, University of Reading.Google Scholar
Shutler, S. M., Bircher, G. M., Tredger, J. A., Morgan, L. M., Walker, A. F. & Low, A. G. (1989). The effect of daily baked beans (Phaseolus vulgaris) consumption on the plasma lipid levels of young, normocholesterolaemic men. British Journal of Nutrition 61, 257–265.CrossRefGoogle ScholarPubMed
Shutler, S. M., Low, A. G. & Walker, A. F. (1988). Comparative effect of four different legume species on the plasma lipid levels of hypercholesterolaemic pigs. Proceedings of the Nutrition Society 47, 124A.Google Scholar
Shutler, S. M., Walker, A. F. & Low, A. G. (1987 a). The cholesterol-lowering effects of legumes. 1. Effects of the major nutrients. Human Nutrition: Food Sciences and Nutrition 41F, 71–86.Google Scholar
Shutler, S. M., Walker, A. F. & Low, A. G. (1987 b). The cholesterol-lowering effects of legumes. 2. Effects of fibre, sterols, saponins and isoflavones. Human Nutrition: Food Sciences and Nutrition 41F, 87–102.Google Scholar
Simons, L. A., Gayst, S., Balasubramaniam, S. & Ruys, J. (1982). Long-term treatment of hypercholesterolaemia with a new palatable formulation of guar gum. Atherosclerosis 45, 101–108.CrossRefGoogle ScholarPubMed
Simpson, H. C. R., Lousley, S., Geekie, M., Simpson, R. W., Carter, R. D., Hockaday, T. D. R. & Mann, J. I. (1981). A high carbohydrate leguminous fibre diet improves all aspects of diabetic control. Lancet i, 1–5.CrossRefGoogle Scholar
Sirtori, C. R., Conti, F., Agradi, E., Mantero, O. & Gatti, E. (1977). Soybean protein diet in the treatment of type II hyperlipoproteinaemia. Lancet i, 275–277.CrossRefGoogle Scholar
Sirtori, C. R., Gatti, E., Mantero, O., Conti, F., Agradi, E., Tremoli, E., Sirtori, M., Fraterrigo, L., Tavazzi, L. & Kritchevsky, D. (1979). Clinical experience with the soybean protein diet in the treatment of hypercholsterolaemia. American Journal of Clinical Nutrition 32, 1645–1658.CrossRefGoogle Scholar
Sirtori, C. R., Zucchi-Dentone, C., Sirtori, M., Gatti, E., Descovich, G. C., Gaddi, A., Cattin, L., Da Col, P. G., Senin, U., Mannarino, E., Avellone, G., Colombo, L., Fragiacomo, C., Noseda, G. & Lenzi, S. (1985). Cholesterol-lowering and HDL-raising properties of lecithinated soy protein in type II hyperlipidaemic patients. Annals of Nutrition and Metabolism 29, 348–357.CrossRefGoogle Scholar
Sparks, J. D. & Sparks, C. E. (1985). Apolipoprotein B and lipoprotein metabolism. Advances in Lipid Research 21, 1–46.CrossRefGoogle ScholarPubMed
Stasse-Wolthuis, M. (1981). Influence of dietary fibre on cholesterol metabolism and colonic function in healthy subjects. World Review of Nutrition and Dietetics 36, 100–140.CrossRefGoogle ScholarPubMed
Story, J. A., LePage, S. L., Petro, M. S., West, L. G., Cassidy, M. M., Lightfoot, F. G. & Vahouny, G. V. (1984). Interactions of alfalfa plant and sprout saponins with cholesterol in vitro and in cholesterol fed rats. American Journal of Clinical Nutrition 39, 917–929.CrossRefGoogle ScholarPubMed
Sturdevant, R. A. L., Pearce, M. L. & Dayton, S. (1973). Increased gallstone prevalence in men on serum cholesterol-lowering diets. New England Journal of Medicine 288, 24–27.CrossRefGoogle Scholar
Tall, A. R. & Small, D. M. (1978). Plasma high density lipoproteins. New England Journal of Medicine 299, 1232–1236.CrossRefGoogle ScholarPubMed
Taskinen, M. R., Kashyap, M. L., Srivastava, L. S., Ashraf, M., Johnson, J. D., Perisutti, G., Brady, D., Glueck, C. J. & Jackson, R. L. (1982). In vitro catabolism of human plasma very low density lipoproteins. Effects of VLDL concentration on the interconversion of high-density lipoprotein subfractions. Atherosclerosis 41, 381–394.CrossRefGoogle ScholarPubMed
Thacker, P. A., Salomons, M. O., Aherne, F. X., Milligan, L. P. & Bowland, J. P. (1981). Influence of propionic acid on the cholesterol metabolism of pigs fed hypercholesterolemic diets. Canadian Journal of Animal Science 61, 969–975.CrossRefGoogle Scholar
Tobin, G. & Carpenter, K. J. (1978). The nutritional value of the dry bean (Phaseolus vulgaris): a literature review. Nutrition Abstracts and Reviews 48A, 919–936.Google Scholar
Tsai, A. C., Mott, E. L., Owen, G. M., Bennick, M. R., Lo, G. S. & Steinke, F. H. (1983). Effects of soybean polysaccharide on gastrointestinal functions, nutrient balance, steroid excretions, glucose tolerance, serum lipids and other parameters in humans. American Journal of Clinical Nutrition 38, 504–511.CrossRefGoogle ScholarPubMed
Tuomilehto, J., Karttunen, P., Vinni, S., Kostiainen, E. & Uusitupa, M. (1983). A double-blind evaluation of guar gum in patients with dyslipidaemia. Human Nutrition: Clinical Nutrition 37C, 109–116.Google Scholar
Turner, P. R., Tuomilehto, J., Happonen, P., LaVille, A. E., Shaikh, M. & Lewis, B. (1990). Metabolic studies on the hypolipidaemic effect of guar gum. Atherosclerosis 81, 145–150.CrossRefGoogle ScholarPubMed
Uusitupa, M., Tuomilheto, J., Karttunen, P. & Wolf, E. (1984). Long-term effects of guar gum on metabolic control, serum cholesterol and blood pressure levels in type 2 (non-insulin dependent) diabetic patients with high blood pressure. Annals of Clinical Research 16, Suppl. 43, 126–131.Google ScholarPubMed
Van Berkel, T. J. C., Kruijt, J. K., Scheek, L. M. & Groot, P. H. E. (1983). Effect of apolipoproteins E and C-III on the interaction of chylomicrons with parenchymal and non-parenchymal cells from rat liver. Biochemical Journal 216, 71–80.CrossRefGoogle ScholarPubMed
van Raaij, J. M. A., Katan, M. B. & Hautvast, J. G. A. J. (1979). Casein, soya protein, serum cholesterol. Lancet i, 958.CrossRefGoogle Scholar
van Raaij, J. M. A., Katan, M. B., Hautvast, J. G. A. J. & Hermus, R. J. J. (1981). Effects of casein versus soy protein diets on serum cholesterol and lipoproteins in healthy young volunteers. American Journal of Clinical Nutrition 34, 1261–1271.CrossRefGoogle Scholar
van Raaij, J. M. A., Katan, M. B., West, C. E. & Hautvast, J. G. A. J. (1982). Influence of diets containing casein, soy isolate and soy concentrate on serum cholesterol and lipoproteins in middle-aged volunteers. American Journal of Clinical Nutrition 35, 925–934.CrossRefGoogle ScholarPubMed
Verrillo, A., de Teresa, A., Giarrusso, Carandente P. & La Rocca, S. (1983). Long-term hypocholesterolaemic activity of soybean protein diet in severe, familial type IIa hyperlipoproteinaemia. Bulletin of Molecular Biology and Medicine 8, 193–198.Google Scholar
Verrillo, A., de Teresa, A., Carandente Giarrusso, P. & La Rocca, S. (1985). Soybean protein diets in the management of type II hyperlipoproteinaemia. Atherosclerosis 54, 321–331.CrossRefGoogle ScholarPubMed
Vessby, B., Karlstrom, B., Lithell, H., Gustafsson, I. B. & Werner, I. (1982). The effects on lipid and carbohydrate metabolism of replacing some animal protein by soy-protein in a lipid lowering diet for hypercholesterolaemic patients. Human Nutrition: Applied Nutrition 36A, 179–189.Google Scholar
Wolfe, B. M. & Giovannetti, P. M. (1985). Elevation of VLDL cholesterol during substitution of soy protein for animal protein in diets of hypercholesterolemic Canadians. Nutrition Reports International 32, 1057–1065.Google Scholar
Wolfe, B. M., Giovannetti, P. M., Cheng, D. C. H., Roberts, D. C. K. & Carroll, K. K. (1981). Hypolipidemic effect of substituting soybean protein isolate for all meat and dairy protein in the diets of hypercholesterolemic men. Nutrition Reports International 24, 1187–1198.Google Scholar
Wursch, P., del Vedovo, S. & Koellreutter, B. (1986). Cell structure and starch nature as key determinants of the digestion rate of starch in legume. American Journal of Clinical Nutrition 43, 25–29.CrossRefGoogle ScholarPubMed
Yudkin, J. (1957). Diet and coronary thrombosis. Hypothesis and fact. Lancet 273, 155–162.CrossRefGoogle ScholarPubMed
Zavoral, J. H., Hannan, P., Fields, D. J., Hanson, M. N., Frantz, I. D., Kuba, K., Elmer, P. & Jacobs, D. R. (1983). The hypolipidemic effect of locust bean gum food products in familial hypercholesterolemic adults and children. American Journal of Clinical Nutrition 38, 285–294.CrossRefGoogle ScholarPubMed