Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-28T03:06:42.877Z Has data issue: false hasContentIssue false
  • English
  • Français

Application of Gold and Platinum Bimetallic Nanoparticle to enhance Surface Plasmon Resonance Signal

Published online by Cambridge University Press:  23 June 2020

Lucca Silva Nascimento Open the ORCID record for Lucca Silva Nascimento [Opens in a new window] ,
Erenildo Ferreira Macedo ,
Jéssica Aparecida Magalhães ,
Luísa Rodrigues Molina Dona'  and
Dayane Batista Tada
Lucca Silva Nascimento
Affiliation:
Laboratory of Nanomaterials and Nanotechnology, Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, Rua Talim 330, Vila Nair, São José dos Campos12231-280, SP, Brazil; [email protected] (L.S.d.N.); [email protected] (E.F.d.M.); [email protected] (J.A. d.M.); [email protected] (L.R.M. d D.).
Erenildo Ferreira Macedo
Affiliation:
Laboratory of Nanomaterials and Nanotechnology, Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, Rua Talim 330, Vila Nair, São José dos Campos12231-280, SP, Brazil; [email protected] (L.S.d.N.); [email protected] (E.F.d.M.); [email protected] (J.A. d.M.); [email protected] (L.R.M. d D.).
Jéssica Aparecida Magalhães
Affiliation:
Laboratory of Nanomaterials and Nanotechnology, Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, Rua Talim 330, Vila Nair, São José dos Campos12231-280, SP, Brazil; [email protected] (L.S.d.N.); [email protected] (E.F.d.M.); [email protected] (J.A. d.M.); [email protected] (L.R.M. d D.).
Luísa Rodrigues Molina Dona'
Affiliation:
Laboratory of Nanomaterials and Nanotechnology, Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, Rua Talim 330, Vila Nair, São José dos Campos12231-280, SP, Brazil; [email protected] (L.S.d.N.); [email protected] (E.F.d.M.); [email protected] (J.A. d.M.); [email protected] (L.R.M. d D.).
Dayane Batista Tada*
Affiliation:
Laboratory of Nanomaterials and Nanotechnology, Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, Rua Talim 330, Vila Nair, São José dos Campos12231-280, SP, Brazil; [email protected] (L.S.d.N.); [email protected] (E.F.d.M.); [email protected] (J.A. d.M.); [email protected] (L.R.M. d D.).
*
*To whom correspondence should be addressed: Dr. Dayane Batista Tada, email: [email protected]
Get access

Abstract

Sensors based on the surface plasmon resonance (SPR) technique are useful devices to detect and monitor interactions between biomolecules in real-time. SPR is a label-free method that monitors the variation of reflectivity of a biochip composed of a metal-coated glass prism and can be applied in several areas, such as biotechnology, food safety and clinical diagnosis. In the last years, several researchers have proven the efficiency of metallic nanoparticles (NPs) in the enhancement of SPR signal. This feature allowed the detection of biomolecules at very low concentration. Aiming to further enhance SPR signal towards the detection of proteins at low concentration and by a simple procedure, the present work compared the performance of gold and platinum bimetallic NPs (AuPtNPs) with that of monometallic gold NPs (AuNPs) in the enhancement of SPR signal. In order to evaluate the NPs, protein peanut agglutin (PNA) was used as target analyte and anti-PNA antibody was used as sensing molecule. Firstly NPs were functionalized with anti-PNA antibody and incubated with a solution containing PNA. Then, the NPs bound to PNA were injected into the SPR equipment containing a biochip previously modified with anti-PNA antibody. The results demonstrated that the AuPtNPs provided a 91-fold increase compared to the direct detection of free PNA in solution. In comparison with AuNPs, the signal generated by AuPtNPs was about 4 times higher. This encouraging result indicated that the application of bimetallic NPs may be a better strategy to further enhance sensitivity of SPR biosensors and could drive the development of new strategies that are not only simple, but also able to detect proteins at low concentrations, which is of great importance, especially in clinical diagnostics.

Type
Articles
Information
MRS Advances , Volume 5 , Issue 42: Nanoscale and Quantum Materials , 2020 , pp. 2181 - 2189
Check for updates
Copyright
Copyright © Materials Research Society 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Tuoriniemi, J., Gorton, L., Ludwig, R., & Safina, G. (2020). Determination of the Distance Between the Cytochrome and Dehydrogenase Domains of Immobilized Cellobiose Dehydrogenase by Using Surface Plasmon Resonance with a Center of Mass Based Model. Analytical Chemistry.CrossRefGoogle ScholarPubMed
Homola, J. (2008). Surface plasmon resonance sensors for detection of chemical and biological species. Chemical reviews, 108(2), 462-493.CrossRefGoogle ScholarPubMed
Jia, Y., Peng, Y., Bai, J., Zhang, X., Cui, Y., Ning, B., … & Gao, Z. (2018). Magnetic nanoparticle enhanced surface plasmon resonance sensor for estradiol analysis. Sensors and Actuators B: Chemical, 254, 629-635.CrossRefGoogle Scholar
Das, C. M., Ouyang, Q., Kang, L., Guo, Y., Dinh, X. Q., Coquet, P., & Yong, K. T. (2020). Augmenting sensitivity of surface plasmon resonance (SPR) sensors with the aid of anti-reflective coatings (ARCs). Photonics and Nanostructures-Fundamentals and Applications, 38, 100760.Google Scholar
Ertürk, G., Uzun, L., Tümer, M. A., Say, R., & Denizli, A. (2011). Fab fragments imprinted SPR biosensor for real-time human immunoglobulin G detection. Biosensors and Bioelectronics, 28(1), 97-104.CrossRefGoogle ScholarPubMed
Makaraviciute, A., Ramanavicius, A., & Ramanaviciene, A. (2015). Development of a reusable protein G based SPR immunosensor for direct human growth hormone detection in real samples. Analytical Methods, 7(23), 9875-9884.CrossRefGoogle Scholar
Wang, J., Munir, A., Li, Z., & Zhou, H. S. (2009). Aptamer–Au NPs conjugates-enhanced SPR sensing for the ultrasensitive sandwich immunoassay. Biosensors and Bioelectronics, 25(1), 124-129.CrossRefGoogle ScholarPubMed
Wang, J., Zhu, Z., Munir, A., & Zhou, HS (2011). Detecção SPR aprimorada por nanopartículas de Fe3O4 para bioensaio em sanduíche ultrassensível. Talanta, 84 (3), 783-788.CrossRefGoogle Scholar
Ferreira de Macedo, E., Ducatti Formaggio, D. M., Salles Santos, N., & Batista Tada, D. (2017). Gold nanoparticles used as protein scavengers enhance surface plasmon resonance signal. Sensors, 17(12), 2765.CrossRefGoogle ScholarPubMed
Magalhães, J. A., Fernandes, A. U., Junqueira, H. C., Nunes, B. C., Cursino, T. A., Formaggio, D. M., … & Tada, D. B. (2019). Bimetallic nanoparticles enhance photoactivity of conjugated photosensitizer. Nanotechnology, 31(9), 095102.CrossRefGoogle ScholarPubMed
He, W., Liu, Y., Yuan, J., Yin, J. J., Wu, X., Hu, X., … & Guo, Y. (2011). Au@ Pt nanostructures as oxidase and peroxidase mimetics for use in immunoassays. Biomaterials, 32(4), 1139-1147.CrossRefGoogle ScholarPubMed
Wang, A., Liu, X. Y., Mou, C. Y., & Zhang, T. (2013). Understanding the synergistic effects of gold bimetallic catalysts. Journal of catalysis, 308, 258-271.CrossRefGoogle Scholar
Formaggio, D.M.D., de Oliveira Neto, X.A., Rodrigues, L.D.A. et al. . In vivo toxicity and antimicrobial activity of AuPt bimetallic nanoparticles. J Nanopart Res 21, 244 (2019). https://doi.org/10.1007/s11051-019-4683-2.CrossRefGoogle Scholar
Boltersdorf, J., Leff, A., Forcherio, G., McClure, J., & Lundgren, C. (2019). Surface Plasmon Resonant Gold-Palladium Bimetallic Nanoparticles for Promoting Catalytic Oxidation. MRS Advances, 4(33-34), 1877-1886. doi:10.1557/adv.2019.222CrossRefGoogle Scholar
Hamid Tayefi Nasrabadi, Elham Abbasi, Davaran, Soodabeh, Kouhi, Mohammad & Akbarzadeh, Abolfazl (2016) Bimetallic nanoparticles: Preparation, properties, and biomedical applications. Artificial Cells, Nanomedicine, and Biotechnology, 44:1, 376-380, DOI: 10.3109/21691401.2014.953632.CrossRefGoogle Scholar
Wang, Jing, Song, Daqian, Wang, Liying, Zhang, Hua, Zhang, Hanqi, Sun, Ying, Design and performances of immunoassay based on SPR biosensor with Au/Ag alloy nanocomposites. Sensors and Actuators B: Chemical, Volume 157, Issue 2, 2011, Pages 547-553, ISSN 0925-4005, https://doi.org/10.1016/j.snb.2011.05.020. (http://www.sciencedirect.com/science/article/pii/S0925400511004217).CrossRefGoogle Scholar
Nanoparticle-Enhanced Surface Plasmon Resonance Detection of Proteins at Attomolar Concentrations: Comparing Different Nanoparticle Shapes and Sizes. Kwon, Min Jeong, Lee, Jaeyoung, Wark, Alastair W., and Lee, Hye Jin Analytical Chemistry 2012 84 (3), 1702-1707; DOI: 10.1021/ac202957h.CrossRefGoogle ScholarPubMed
Zeng, Shuwen, Yu, Xia, Law, Wing-Cheung, Zhang, Yating, Hu, Rui, Dinh, Xuan-Quyen, Ho, Ho-Pui, Yong, Ken-Tye, Size dependence of Au NP-enhanced surface plasmon resonance based on differential phase measurement. Sensors and Actuators B: Chemical, Volume 176, 2013, Pages 1128-1133, ISSN 0925-4005, https://doi.org/10.1016/j.snb.2012.09.073. (http://www.sciencedirect.com/science/article/pii/S0925400512009860).CrossRefGoogle Scholar
Nanomaterials enhanced surface plasmon resonance for biological and chemical sensing applications. Zeng, S., Baillargeat, D., Ho, H. and Yong, K., Chem. Soc. Rev., 2014, 43, 3426. DOI: 10.1039/C3CS60479ACrossRefGoogle ScholarPubMed
Ko, W-Y, Chang, C-Y, Chiang, Y-T, Huang, L-T, Huang, L-W, Lin, K-J. Immunoassay of plasmonic gold-nanoparticle clusters: Plasmon coupling effects for Parkinson biomarker detection. J Chin Chem Soc. 2019;1–6. https://doi.org/10.1002/jccs.201900072Google Scholar