Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-30T23:29:10.074Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of some organic binders on the mechanical strength of hydroxyapatite-based biocements

Published online by Cambridge University Press:  24 October 2018

Jorge López-Cuevas Open the ORCID record for Jorge López-Cuevas [Opens in a new window] ,
Gregorio Vargas-Gutiérrez ,
José Luis Rodríguez-Galicia  and
Juan Carlos Rendón-Angeles
Jorge López-Cuevas*
Affiliation:
Center for Research and Advanced Studies (CINVESTAV), Saltillo Campus, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP 25900.
Gregorio Vargas-Gutiérrez
Affiliation:
Center for Research and Advanced Studies (CINVESTAV), Saltillo Campus, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP 25900.
José Luis Rodríguez-Galicia
Affiliation:
Center for Research and Advanced Studies (CINVESTAV), Saltillo Campus, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP 25900.
Juan Carlos Rendón-Angeles
Affiliation:
Center for Research and Advanced Studies (CINVESTAV), Saltillo Campus, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP 25900.
*
*Corresponding author’s email: [email protected]
Get access

Abstract

In the present study, aiming to control the setting reaction and to increase the strength of hydroxyapatite-based biocements, gelatin, citric acid and malonic acid, and combinations of them, were used as binders. The mechanical strength of the developed biocements was evaluated after 1 to 15 days of exposure (aging) to air with 100% relative humidity at 37-40 °C. Especially for the case of gelatin, the mechanical properties of the biocements increased as a function of aging time in the humid environment. In this case, the standard compressive strength increased from ∼19 to ∼40 MPa, while the diametral compressive strength increased from ∼2 to ∼12 MPa, between day 1 and day 15 of aging. These values are similar to those reported in the past for HAp-containing biocements added with a variety of organic or inorganic binders. However, the resulting setting times were too long. Thus, it was proposed that crosslinking of gelatin by a suitable chemical agent during the application of the prepared HAp-based biocements could be a potential way to control their handling and setting characteristics, while preserving their good mechanical properties, good biocompatibility, and good solubilization characteristics in the presence of biological fluids.

Keywords

biomaterialcement & ampconcretestrengthceramic
Type
Articles
Information
MRS Advances , Volume 3 , Issue 62: International Materials Research Congress XXVII , 2018 , pp. 3729 - 3734
Copyright
Copyright © Materials Research Society 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

López-Cuevas, J., Rendón-Angeles, J.C., Rodríguez-Galicia, J.L. and Gutiérrez-Chavarría, C.A., MRS Advances 2, 3851-3857 (2017).CrossRefGoogle Scholar
Ginebra, M.P., Boltong, M.G., Fernandez, E., Planell, J.A. and Driessens, F.C.M., in Transactions of the 21st. Annual Meeting of the Society for Biomaterials in Conjunction with the 27th International biomaterials symposium, (San Francisco, California, USA, 1995) p. 99.Google Scholar
Dorozhkin, Sergey V., J. Funct. Biomater. 4, 209-311 (2013).CrossRefGoogle Scholar
O’Neill, R., McCarthy, H.O., Montufar, E.B., Ginebra, M.-P., Wilson, D.I., Lennon, A., Dunne, N., Acta Biomater . 50, 1-19 (2017).CrossRefGoogle Scholar
Nagose, M. and Chen, R., J. Oral Maxillo. Surg. 149, 1305-1309 (1995).Google Scholar
Brown, W.E. and Chow, L.C., in Cements Research Progress, edited by Brown, P.W. (American Ceramic Society, Westerville, OH, USA, 1986) pp. 351-379.Google Scholar
Otsuka, M., Matsuda, Y., Suwa, Y. and Fox, J.L., J. Biomed. Mater. Res. 29, 25-32 (1995).CrossRefGoogle Scholar
Mirtchi, A.A. and Lemaitre, J., Biomaterials 11, 83-88 (1990).CrossRefGoogle Scholar
Vargas, G., Acevedo, J.L., López, J. and Romero, J., Mater. Lett. 62, 3656-3658 (2008).CrossRefGoogle Scholar
Fernandes, F.M., Darder, M., Ruiz, A.I., Aranda, P. and Ruiz-Hitzky, E., in Nanocomposites with Biodegradable Polymers: Synthesis, Properties, and Future Perspectives, Serie Monographs on the Physics and Chemistry of Materials, edited by Mittal, V. (Oxford University Press, UK, 2011) pp. 209-233.CrossRefGoogle Scholar