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The Effects of Smoking Cessation on the Risk Factors for the Metabolic Syndrome: A Follow-Up Study of Veterans

Published online by Cambridge University Press:  06 April 2016

Akbar Sharip ,
Anthony Firek  and
Serena Tonstad
Akbar Sharip*
Affiliation:
Department of Preventive Medicine, The Loma Linda University School of Medicine, Loma Linda, California 92354, USA
Anthony Firek
Affiliation:
Endocrinology Department, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, California 92354, USA
Serena Tonstad
Affiliation:
School of Public Health, The Loma Linda University, Loma Linda, California 92354, USA
*
Address for correspondence: Akbar Sharip, Department of Preventive Medicine Office, Loma Linda University, Evans Hall, Rm. 101 24785 Stewart Street Loma Linda, California 92350. Email: [email protected]
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Abstract

Objective: To evaluate the impact of short-term smoking cessation on Metabolic Syndrome (Mets) component risk factors, and hormones related to MetS and human metabolism.

Methods: Smoking veterans with MetS, attending stop smoking class, were followed up close to one year. Paired comparisons between after the follow up and baseline data were made using t-test.

Results: A total of 95 smoking veterans with MetS completed average close to one year follow up. Thirty subjects completely quit for the average of 6 months, while 36 subjects continued smoking during the follow up. At the end of study, quitters average waist circumference increased 2.98 cm (0.69–5.27), weight increased 2.05 kg (−0.03 to 4.13), HDL cholesterol increased 4.17 mg/dl (1.03–7.32), triglyceride decreased 56.17 mg/dl ((−1.96 to 111.20), and MetS prevalence decreased 13% (p = 0.05). The changes in ghrelin were moderately positively associated with duration of quitting smoking (R2 = 43.99, and p < 0.01).

Conclusion: Compared to the baseline, quitters HDL was up, triglyceride was down, and overall MetS prevalence was lower. The longer the duration of quitting, bigger the increase in ghrelin. There were no significant changes in serum leptin, ghrelin, serum insulin, and insulin resistance after quitting smoking.

Type
Original Articles
Information
Journal of Smoking Cessation , Volume 12 , Issue 3 , September 2017 , pp. 143 - 152
Copyright
Copyright © The Author(s) 2016 

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