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Published online by Cambridge University Press: 19 February 2018
Hippocrates was the first to regard epilepsy, not as a “sacred disease” but as a disorder due to natural causes. He believed that a causal relationship existed between humidity of the brain and the epileptic crisis—a hypothesis that in recent years has assumed prominence following the work of Temple Fay (27) and McQuarrie (28). According to Fay an abnormal increase in intracranial pressure is brought about by the accumulation of fluid over the cortex, due to impairment of function of the Pacchionian bodies.
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