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Intensive Cortisone Therapy in Schizophrenia

Published online by Cambridge University Press:  08 February 2018

Linford Rees  and
G. M. King
Linford Rees
Affiliation:
Bethlem Royal and Maudsley Hospitals
G. M. King
Affiliation:
St. Cadoc's Hospital, Caerleon
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Extract

Cortisone therapy has been claimed to produce favourable results in clinical schizophrenics (Cohn and Karnosh, 1951; Cohn et al., 1953). Rees and King (1952) carried out a controlled investigation on the effects of Cortisone given in moderate doses over a four-day period to a group of schizophrenic patients and found no significant changes in symptomatology, behaviour or in a series of psychological and physiological tests.

In a personal communication Dr. Cohn suggested that Cortisone given in higher doses over a longer period would probably be therapeutically more effective in chronic schizophrenia.

The present paper describes a controlled investigation into the therapeutic effects of Cortisone given in high dosage over a relatively prolonged period.

Type
Original Articles
Information
Journal of Mental Science , Volume 102 , Issue 426 , January 1956 , pp. 155 - 159
Copyright
Copyright © Royal College of Psychiatrists, 1956 

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References

Cohn, J. B., and Karnosh, L. J., Dis. Nerv. System. 1951, 12, 291.Google Scholar
Cohn, J. B., Steckler, M. A., and Rubinstein, M. A., J. Clin. and Exp. Psychopath., 1953, 14, 161.Google Scholar
Eysenck, H. J., Rees, L., and Himmelweit, H., Dimensions of Personality, 1947. London.Google Scholar
Hogben, L., Med. Press, 1954, 232 Google Scholar
Rees, Linford, and King, G. M., J. Ment. Sci., 1952, 98, 412.CrossRefGoogle Scholar
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