Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-20T17:35:06.887Z Has data issue: false hasContentIssue false
  • English
  • Français

Treatment of recurrent respiratory papillomatosis with argon plasma coagulation

Published online by Cambridge University Press:  29 June 2007

W. Bergler ,
M. Hönig ,
K. Götte ,
G. Petroianu  and
K. Hörmann
W. Bergler*
Affiliation:
Department of Otorhinolaryngology, University Clinic Mannheim, Germany.
M. Hönig
Affiliation:
Department of Otorhinolaryngology, University Clinic Mannheim, Germany.
K. Götte
Affiliation:
Department of Otorhinolaryngology, University Clinic Mannheim, Germany.
G. Petroianu
Affiliation:
Department of Otorhinolaryngology, University Clinic Mannheim, Germany.
K. Hörmann
Affiliation:
Department of Otorhinolaryngology, University Clinic Mannheim, Germany.
*
Address for correspondence: PD. Dr W. F. Bergler, Univ.-HNO-Klinik, Klinikum, 68135 Mannheim, Germany. Fax: 621-383-3827
Get access Rights & Permissions [Opens in a new window]

Abstract

Extension of recurrent respiratory papillomatosis (RRP) to the lower airway in children is life-threatening and an extremely difficult condition to treat. We present the case of a seven-year-old girl with progressive RRP since the age of two. Repeated CO2 laser treatment and interferon-alpha treatment could not prevent tracheotomy and spread to the trachea. We used argon plasma coagulation (APC) with flexible endoscopy for the first time for the treatment of RRP. APC gives a controlled limited penetration into the tissue and good control of bleeding. There is no carbonization or vaporization which makes it a suitable method for the treatment of lower airway RRP. After a few treatments with APC, we gained very good control of the disease with no side-effects or complications. The described application of APC seems to be a promising way to treat lower airway RRP.

Keywords

Papillomatosisrecurrent respiratoryAirway obstructionLaser surgeryArgon plasma coagulation
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 4 , April 1997 , pp. 381 - 384
Copyright
Copyright © JLO (1984) Limited 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abramson, A. L., Steinberg, B. M., Winkler, B. (1987) Laryngeal papillomatosis: Clinical, histopathologic and molecular studies. Laryngoscope 97: 678–685.CrossRefGoogle ScholarPubMed
Benjamin, B., Parson, D. S. (1988) Recurrent respiratory papillomatosis: a 10-year study. Journal of Laryngology and Otology 102: 1022–1028.CrossRefGoogle ScholarPubMed
Doyle, D. J., Gianoli, G. J., Espinola, T., Miller, R. H. (1994) Recurrent respiratory papillomatosis: juvenile versus adult forms. Laryngoscope 104: 523–527.CrossRefGoogle ScholarPubMed
Farin, G., Grund, K. E. (1994) Technology of argon plasma coagulation with particular regard to endoscopic applications. Endoscopic Surgery and Allied Technologies 2: 71–77.Google ScholarPubMed
Feyh, J., Gutmann, R., Leunig, A. (1993) Die photodynamische Lasertherapie im Bereich der Hal-, Nasen-, Ohrenheilkunde. Laryngo-Rhino-Otologie 72: 273–278.CrossRefGoogle Scholar
Gerein, V., Lodmann, E., Bell, G., von Illberg, C., Kornhuber, B. (1987) Result of long-term leukocyte interferon (alpha IFN) therapy using an individually determined dose schedule in recurrent laryngeal papillomatosis. Klinische Pädiatrie 199: 224–229.CrossRefGoogle ScholarPubMed
Grund, K. E., Sorek, D., Farin, G. (1994) Endoscopic argon plasma coagulation (APC) First clinical experiences in flexible endoscopy. Endoscopic Surgery and Allied Technologies 2: 42–46.Google ScholarPubMed
Kashima, H., Leventhal, B., Clark, B. (1988) Interferon alfa- N1 (Wellferon) in juvenile onset recurrent respiratory papillomatosis: Results of a randomized study of twelve collaborative institutions. Laryngoscope 98: 334–340.CrossRefGoogle ScholarPubMed
Lippmann, S. M., Donovan, D. T., Frankenthaler, R. A., Weber, R. S., Early, C. L., Hong, W. K., Goepfert, H. (1994) 13-cis-retinoic acid plus interferon-α2a in recurrent respiratory papillomatosis. Journal of the National Cancer Institute 86: 859–861.CrossRefGoogle Scholar
Lundquist, P., Haglund, S., Carlsöö, B., Strander, H., Lundgren, E. (1984) Interferon therapy in juvenile laryngeal papillomatosis. Otolaryngology, Head and Neck Surgery 92: 386–391.CrossRefGoogle ScholarPubMed
Mehta, P., Herold, N. (1980) Regression of juvenile laryngobronchial papillomatosis with systemic bleomycin therapy. Journal of Pediatrics 97: 479–484.CrossRefGoogle ScholarPubMed
Morgan, A. L. T., Zeitsch, R. P. (1986) Recurrent respiratory papillomatosis in children: a retrospective study of management and complications. Ear, Nose and Throat Journal 65: 403–409.Google ScholarPubMed
Morrison, G. A., Evans, J. N. (1993) Juvenile respiratory papillomatosis: acyclovir reassessed. International Journal of Pediatric Otorhinolaryngologie 26: 193–197.CrossRefGoogle ScholarPubMed
Morrison, G. A. J., Kotecha, B., Evans, G. (1993) Ribavirin treatment for juvenile respiratory papillomatosis. Journal of Laryngology and Otology 107: 423–426.CrossRefGoogle ScholarPubMed
Padayachee, A., Prescott, C. A. (1993) Relationship between the clinical course and HPV typing of recurrent laryngeal papillomatosis. The Red Cross war memorial children's hospital experience 1982–1988. International Journal of Pediatric Otorhinolaryngologie 26: 141–147.CrossRefGoogle ScholarPubMed
Pou, A. M., Rimell, F. L., Jordan, J. A., Shoemaker, D. L., Johson, J. T., Barua, P., Post, J. C., Ehrlich, G. D. (1995) Adult respiratory papillomatosis: human papillomavirus type and viral coinfections as predictors of prognosis. Annals of Otology, Rhinology and Laryngology 104: 758–762.CrossRefGoogle ScholarPubMed
Sessler, M. J., Becker, H.-D., Flesch Grund, K.-E. (1995) Therapeutic effect of argon plasma coagulation on small malignant gastrointestinal tumours. Journal of Cancer Research and Clinical Oncology 121: 235–238.CrossRefGoogle Scholar
Walther, E. K., Herberhold, C. (1993) Treatment of laryngotracheal papillomatosis with combined use of laser surgery and intralesional administration of alpha-interferon (Roferon). Laryngorhinootologie 72: 485–491.CrossRefGoogle ScholarPubMed
Willging, J. P. (1995) Laryngeal neoplasmas-respiratory papilloma. In The Pediatric Airway. (Myer, C. M. III, Cotton, R. T., Short, S. R., eds.) J. B. Lippincott Company, Philadelphia, pp 263–266.Google Scholar