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Small cell neuroendocrine carcinoma in the petrous apex

Published online by Cambridge University Press:  25 November 2005

Lana Kovač ,
Mislav Gjurić ,
Srećko Branica ,
Krsto Dawidowsky  and
Sven Seiwerth
Lana Kovač
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center, Zagreb, Croatia
Mislav Gjurić
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center, Zagreb, Croatia
Srećko Branica
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center, Zagreb, Croatia
Krsto Dawidowsky
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center, Zagreb, Croatia
Sven Seiwerth
Affiliation:
Department of Pathology, University Hospital Zagreb, Zagreb, Croatia
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Abstract

With the exception of moderately differentiated neuroendocrine carcinoma of the larynx, neuroendocrine carcinomas are very rare head and neck malignancies. We report a case of a small cell neuroendocrine carcinoma in the petrous apex of the temporal bone. This unusual site for this tumour has not yet been reported in the literature. We confirmed the location and extent of the primary tumour by positron-emission tomography scan. The final histopathological diagnosis was of small cell carcinoma, and this was confirmed by immunohistochemistry. We treated this patient with surgery followed by radiotherapy and chemotherapy. After the treatment was completed there was subtotal remission of the tumour, with no distant metastases.

Keywords

CarcinomaNeuroendocrineCarcinomaSmall CellTemporal BoneSkull Base
Type
Clinical Record
Information
The Journal of Laryngology & Otology , Volume 120 , Issue 1 , January 2006 , pp. 74 - 76
Copyright
2005 JLO (1984) Limited

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