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Microbiology of otitis media in Indigenous Australian children: review

Published online by Cambridge University Press:  16 January 2017

J Jervis-Bardy ,
A S Carney ,
R Duguid  and
A J Leach
J Jervis-Bardy*
Affiliation:
Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin
A S Carney
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Flinders University, Adelaide, Australia
R Duguid
Affiliation:
Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin
A J Leach
Affiliation:
Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin
*
Address for correspondence: Dr Jake Jervis-Bardy, Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia E-mail: [email protected]
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Abstract

Objectives:

To review research addressing the polymicrobial aetiology of otitis media in Indigenous Australian children in order to identify research gaps and inform best practice in effective prevention strategies and therapeutic interventions.

Methods:

Literature review.

Results:

Studies of aspirated middle-ear fluid represented a minor component of the literature reviewed. Most studies relied upon specimens from middle-ear discharge or the nasopharynx. Culture-based middle-ear discharge studies have found that non-typeable Haemophilus influenzae and Streptococcus pneumoniae predominate, with Moraxella catarrhalis, Staphylococcus aureus and Streptococcus pyogenes isolated in a lower proportion of samples. Alloiococcus otitidis was detected in a number of studies; however, its role in otitis media pathogenesis remains controversial. Nasopharyngeal colonisation is a risk factor for otitis media in Indigenous infants, and bacterial load of otopathogens in the nasopharynx can predict the ear state of Indigenous children.

Conclusion:

Most studies have used culture-based methods and specimens from middle-ear discharge or the nasopharynx. Findings from these studies are consistent with international literature, but reliance on culture may incorrectly characterise the microbiology of this condition. Advances in genomic technologies are now providing microbiologists with the ability to analyse the entire mixed bacterial communities (‘microbiomes’) of samples obtained from Indigenous children with otitis media.

Keywords

Otitis MediaIndigenous PopulationMicrobiologyReviewMiddle Ear
Type
Review Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Supplement S2: ASOHNS Supplement , July 2017 , pp. S2 - S11
Copyright
Copyright © JLO (1984) Limited 2017 

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