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Laryngeal carcinoma ex-papilloma in a non-irradiated, non-smoking patient: a clinical record and review of the literature

Published online by Cambridge University Press:  29 June 2007

Suhel Hasan*
Affiliation:
Departments of Otolaryngology – Head and Neck Surgery, St John's Medical Medical College and Hospital, Sarjapur Road, Bangalore 560 034, India.
Sunil N. Dutt
Affiliation:
Departments of Otolaryngology – Head and Neck Surgery, St John's Medical Medical College and Hospital, Sarjapur Road, Bangalore 560 034, India.
Usha Kini
Affiliation:
Departments of Pathology. St John's Medical College and Hospital, Sarjapur Road, Bangalore 560 034, India.
Shameem Shariff
Affiliation:
Departments of Pathology. St John's Medical College and Hospital, Sarjapur Road, Bangalore 560 034, India.
K. M. Nalinesha
Affiliation:
Departments of Otolaryngology – Head and Neck Surgery, St John's Medical Medical College and Hospital, Sarjapur Road, Bangalore 560 034, India.
Devi Prasad
Affiliation:
Departments of Otolaryngology – Head and Neck Surgery, St John's Medical Medical College and Hospital, Sarjapur Road, Bangalore 560 034, India.
*
Dr Suhel Hasan, Department of Otolaryngology – Head and Neck Surgery, St John's Medical College and Hospital, Sarjapur Road, Bangalore – 560 034. India.

Abstract

Malignant transformation of respiratory papillomata is not uncommon in the presence of precipitating factors such as tobacco smoking and therapeutic irradiation. Respiratory papilloma changing to carcinoma in the absence of smoking and irradiation is seldom seen, with only about 20 documented cases presented in the literature. Here we report one such case in a 30-year-old male patient.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1995

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References

Abramson, A. L., Steinberg, B. M., Winkler, B. (1987) Laryngeal papillomatosis: clinical, histopathologic and molecular studies. Laryngoscope 97(6): 678685.CrossRefGoogle ScholarPubMed
Bewtra, C., Krishnan, R., Lee, S. S. (1982) Malignant changes in nonirradiated juvenile laryngotracheal papillomatosis. Archives of Otolaryngology 108: 114116.CrossRefGoogle ScholarPubMed
Branch, B. B., Klein, R. C., Mathews, A. J., Cook, E. W. (1978) Papillomatosis of the respiratory tract – upper airway obstruction and carcinoma. Archives of Otolaryngology 104: 413416.CrossRefGoogle Scholar
Byrne, J. C., Tsao, M. S., Fraser, R. S., Howley, P. M. (1987) Human papilloma virus – 11 DNA in a patient with chronic laryngotracheobronchial papillomatosis and metastatic squamous cell carcinoma of the lung. New England Journal of Medicine 317: 873878.CrossRefGoogle Scholar
Chaput, M., Ninane, J., Gosseye, S. (1989) Juvenile laryngeal papillomatosis and epidermoid carcinoma. Journal of Pediatrics 114: 269272.CrossRefGoogle ScholarPubMed
Dallimore, N. S. (1985) Squamous bronchial carcinoma arising in a case of multiple juvenile papillomatosis. Thorax 40: 797798.CrossRefGoogle Scholar
Gissmann, L., Wolnik, L., Ikenberg, H. (1983) Human papilloma virus types 6 and 11, DNA sequence in genital and laryngeal papillomas and in some cervical cancers. Proceedings of the National Academy of Sciences USA 80: 560563.CrossRefGoogle Scholar
Guillou, L., Sahli, R., Chaubert, P., Monnier, P., Cuttat, J. F., Costa, J. (1991) Squamous cell carcinoma of the lung in a nonsmoking nonirradiated patient with juvenile laryngotracheal papillomatosis: evidence of human papilloma virus – 11 DNA in both carcinoma and papillomas. American Journal of Surgical Pathology 15(9): 891898.CrossRefGoogle Scholar
Guyot, J. P., Lehmann, W., Konfino, O., Kurt, A. M. (1988) Papillomatose juvenile et degenerescence maligne. A propos de deux cas non-irradies. Aktuelle Probleme der Otorhinolaryngologie 12: 6873.Google Scholar
Helmuth, R. A., Strate, R. W. (1987) Squamous carcinoma of the lung in a nonirradiated nonsmoking patient with juvenile laryngotracheal papillomatosis. American Journal of Surgical Pathology 11: 643650.CrossRefGoogle Scholar
Justus, J., Baerthold, W., Preibisch-Effenberger, R. (1970) Juvenile larynxpapillomatose mit ausbreitung uber das tracheobronhcialsystem und maligne entartung ohne stahlentherapie. HNO 18: 349354.Google Scholar
Kashima, H., Wu, T., Mounts, P., Heffner, D.Cachay, A., Hyams, V. (1988) Carcinoma ex-papilloma: histologic and virologic studies in whole-organ sections of the larynx. Laryngoscope 98: 619624.CrossRefGoogle ScholarPubMed
Keim, R. (1980) Malignant change of laryngeal papillomas: a case report. Otolaryngology–Head and Neck Surgery 88: 773777.CrossRefGoogle ScholarPubMed
Kirchner, J. A. (1951) Papilloma of the larynx with extensive lung involvement. Laryngoscope 61: 10221029.CrossRefGoogle ScholarPubMed
Lim, R. Y., Chang, H. (1987) Malignant degeneration of a laryngeal papilloma. Otolaryngology Head and Neck Surgery 96: 559561.Google Scholar
Mackenzie, M. (1871) Essay on growths in the Larynx. J. and A. Churchill, London.Google Scholar
Matsuba, H. M., Thawley, S. E., Spector, G. J., Mauney, M., Pikul, F. J. (1985) Laryngeal epidermoid carcinoma associated with juvenile laryngeal papillomatosis. Laryngoscope 95: 12641266.CrossRefGoogle ScholarPubMed
Mounts, P., Shah, K. V., Kashima, H. (1982) Viral aetiology of juvenile and adult-onset squamous papilloma of the larynx. Proceedings of the National Academy of Sciences USA 79: 54255429.CrossRefGoogle ScholarPubMed
Olofsson, J., Bjelkenkrantz, K., Grontoft, O. (1980) Malignant degeneration of a juvenile laryngeal papilloma: a follow up study. Journal of Otolaryngology 9: 329333.Google ScholarPubMed
Parichartikanond, P., Ratanarapee, S., Sinrachtanand, C. (1982) Carcinomatous transformation of juvenile squamous cell papillomas of the larynx and tracheobronchial tree. Journal of the Medical Association of Thailand 65: 499504.Google ScholarPubMed
Rabbett, W. F. (1965) Juvenile laryngeal papillomatosis – the relation of irradiation to malignant degeneration in this disease. Annals of Otology, Rhinology and Laryngology 74: 11491163.CrossRefGoogle ScholarPubMed
Runckel, D., Kessler, S. (1980) Bronchogenic squamous carcinoma in nonirradiated juvenile laryngotracheal papillomatosis. American Journal of Surgical Pathology 4: 293296.CrossRefGoogle ScholarPubMed
Schnadig, V. J., Clark, W. D., Clegg, T. J., Yao, C. S. (1986) Invasive papillomatosis and squamous carcinoma complicating juvenile laryngeal papillomatosis. Archives of Otolaryngology, Head and Neck Surgery 112: 966971.CrossRefGoogle ScholarPubMed
Schouten, T. J., Van Den Brock, P., Cremers, C. W. R. J., Jongerius, C. M., Meyer, J. W. R., Vooys, G. P. (1983) Interferons and bronchogenic carcinoma in juvenile laryngeal papillomatosis. Archives of Otolaryngology 109: 289291.CrossRefGoogle ScholarPubMed
Shapiro, S. L. (1968) Juvenile laryngeal papillomatosis. Eye, Ear, Nose, Throat Monthly 47: 396400.Google Scholar
Siegel, S. E., Cohen, S. R., Isaacs, H. Jr., Stanley, P. (1979) Malignant transformation of tracheobronchial juvenile papillomatosis without prior radiotherapy. Annals of Otolaryngology 88: 192197.Google ScholarPubMed
Singh, B., Ramsaroop, R. (1994) Clinical features of malignant transformation in benign laryngeal papillomata. Journal of Laryngology and Otology 108: 642648.CrossRefGoogle ScholarPubMed
Solomon, D., Smith, R. R. L., Kashima, H. K., Leventhal, B. G. (1985) Malignant transformation in nonirradiated recurrent respiratory papillomatosis. Laryngoscope 95: 900904.CrossRefGoogle ScholarPubMed
Strong, M. S., Vaughan, C. W., Cooperband, S. R., Healy, G. B., Clemente, M. A. C. P. (1976) Recurrent respiratory papillomatosis: management with the CO2 laser. Annals of Otology, Rhinology and Laryngology 85: 508516.CrossRefGoogle ScholarPubMed
Toso, G. (1971) Epithelial papillomas — benign or malignant. Laryngoscope 81: 15241531.CrossRefGoogle ScholarPubMed
Weiss, M. D., Kashima, H. K. (1983) Tracheal involvement in laryngeal papillomatosis. Laryngoscope 93: 4548.CrossRefGoogle ScholarPubMed
Zarod, A. P., Rutherford, J. D., Corbitt, G. (1988) Malignant progression of laryngeal papilloma associated with human papilloma virus type 6 (HPV 6), DNA. Journal of Clinical Pathology 41: 280283.CrossRefGoogle ScholarPubMed
Zehnder, P. R., Lyons, O. D. (1975) Carcinoma and juvenile papillomatosis. Laryngoscope 85: 614618.Google Scholar