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Incidental head and neck findings on 18F-fluoro-deoxy-glucose positron emission tomography computed tomography

Published online by Cambridge University Press:  24 July 2015

S P Williams ,
A J Kinshuck ,
C Williams ,
R Dwivedi ,
H Wieshmann  and
T M Jones
S P Williams*
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Aintree University Hospital, Liverpool, UK
A J Kinshuck
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Aintree University Hospital, Liverpool, UK
C Williams
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Aintree University Hospital, Liverpool, UK
R Dwivedi
Affiliation:
Department of Radiology, Aintree University Hospital, Liverpool, UK
H Wieshmann
Affiliation:
Department of Radiology, Aintree University Hospital, Liverpool, UK
T M Jones
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Aintree University Hospital, Liverpool, UK Department of Molecular and Clinical Cancer Medicine, University of Liverpool, UK
*
Address for correspondence: Mr S Williams, Department of Otolaryngology and Head and Neck Surgery, Aintree University Hospital, Liverpool L9 7AL, UK E-mail: [email protected]
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Abstract

Objective:

The overlapping risk factors for lung and head and neck cancer present a definite risk of synchronous malignant pathology. This is the first study to specifically review incidental positron emission tomography computed tomography findings in the head and neck region in lung carcinoma patients.

Methods:

A retrospective review was performed of all lung cancer patients who underwent positron emission tomography computed tomography imaging over a five-year period (January 2008 – December 2012), identified from the Liverpool thoracic multidisciplinary team database.

Results:

Six hundred and nine patients underwent positron emission tomography computed tomography imaging over this period. In 76 (12.5 per cent) scans, incidental regions of avid 18F-fluoro-deoxy-glucose uptake were reported in the head and neck region. In the 28 patients who were fully investigated, there were 4 incidental findings of malignancy.

Conclusion:

In lung cancer patients undergoing investigative positron emission tomography computed tomography scanning, a significant number will also present with areas of clinically significant 18F-fluoro-deoxy-glucose uptake in the head and neck region. Of these, at least 5 per cent may have an undiagnosed malignancy.

Keywords

Positron-Emission Tomography18F FluorodeoxyglucoseIncidental FindingsHead and Neck Neoplasms
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 129 , Issue 9 , September 2015 , pp. 898 - 902
Copyright
Copyright © JLO (1984) Limited 2015 

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References

1Bar-Shalom, R, Valdivia, AY, Blaufox, D. PET imaging in oncology. Semin Nucl Med 2000;30:150–85CrossRefGoogle ScholarPubMed
2Ozkol, V, Alper, E, Aydin, N, Ozkol, HF, Topal, NB, Akpinar, AT. The clinical value of incidental 18F-fluorodeoxyglucose-avid foci detected on positron emission tomography/computed tomography. Nucl Med Commun 2010;31:128–36CrossRefGoogle ScholarPubMed
3Beatty, JS, Williams, HT, Aldridge, BA, Hughes, MP, Vasudeva, VS, Gucwa, AL et al. Incidental PET/CT findings in the cancer patient: how should they be managed? Surgery 2009;146:274–81CrossRefGoogle ScholarPubMed
4Ghosh, SK, Roland, NJ, Kumar, A, Tandon, S, Lancaster, JL, Jackson, SR et al. Detection of synchronous lung tumors in patients presenting with squamous cell carcinoma of the head and neck. Head Neck 2009;31:1563–70CrossRefGoogle ScholarPubMed
5Houghton, DJ, Hughes, ML, Garvey, C, Beasley, NJ, Hamilton, JW, Gerlinger, I et al. Role of chest CT scanning in the management of patients presenting with head and neck cancer. Head Neck 1998;20:614–183.0.CO;2-J>CrossRefGoogle ScholarPubMed
6Cook, GJ, Fogelman, I, Maisey, MN. Normal physiological and benign pathological variants of 18-fluoro-2-deoxyglucose positron-emission tomography scanning: potential for error in interpretation. Semin Nucl Med 1996;26:308–14CrossRefGoogle ScholarPubMed
7Zimmer, L, Snyderman, CH, Fukui, M, Blodgett, T, McCook, B, Townsend, DW et al. The use of combined PET/CT for localizing recurrent head and neck cancer: the Pittsburgh experience. Ear Nose Throat J 2005;84:108–10CrossRefGoogle ScholarPubMed
8Roland, NJ, Paleri, V, eds. Head and Neck Cancer: Multidisciplinary Management Guidelines, 4th edn.London: ENT UK, 2011Google Scholar
9Schoder, H, Carlson, DL, Kraus, DH, Stambuk, HE, Gonen, M, Erdi, YE et al. 18F-FDG PET/CT for detecting nodal metastases in patients with oral cancer staged N0 by clinical examination and CT/MRI. J Nucl Med 2006;47:755–62Google ScholarPubMed
10Agress, H Jr, Cooper, BZ. Detection of clinically unexpected malignant and premalignant tumors with whole-body FDG PET: histopathologic comparison. Radiology 2004;230:417–22CrossRefGoogle ScholarPubMed
11Cho, SH, Kim, SW, Kim, WC, Park, JM, Yoo, IR, Kim, SH et al. Incidental focal colorectal 18F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography World J Gastroenterol 2013;19:3453–8CrossRefGoogle ScholarPubMed
12Al-Hakami, HA, Makis, W, Anand, S, Mlynarek, A, Black, MJ, Stern, J et al. Head and neck incidentalomas on positron emission tomographic scanning: ignore or investigate? J Otolaryngol Head Neck Surg 2011;40:384–90Google ScholarPubMed