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Fatal human cyclical neutropenia with unresolving tonsillitis and bilateral cervical abscesses

Published online by Cambridge University Press:  29 June 2007

C. Bandason  and
R. J. Lee
C. Bandason
Affiliation:
Kettering
R. J. Lee*
Affiliation:
Kettering
*
Mr R. J. Lee, M.A., M.D., F.R.C.S.I., Consultant ENT Surgeon, Kettering General Hospital, Rothwell Road, Kettering, Northants NN16 8UZ.
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Abstract

Human Cyclical Neutropenia is a rare haematological disorder, characterized by periodic oscillations in peripheral neutrophil levels from normal to neutropenic, during which patients experience ulcerative stomatitis, fever, malaise and occasional cutaneous and subcutaneous infections.

We present our experience with a fatal case of Human Cyclical Neutropenia together with a brief review of the literature and diagnostic criteria. The paper aims to heighten the clinical awareness of the otolaryngologist to the condition. Close co-operation with the haematologist is essential both for diagnosis and management.

Keywords

Neutropenia, cyclicalTonsillitis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 6 , June 1991 , pp. 487 - 488
Copyright
Copyright © JLO (1984) Limited 1991

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References

Dresch, C., Thevenieau, D., Castro Malaspina, H., Faile, A. (1977) Cell kinetics in human cyclic neutropenia. Scandinavian Journal of Haematology, 19: 14–24.CrossRefGoogle ScholarPubMed
Guerry, D., Dale, D. C., Omine, M., Perry, S., Wolff, S. M. (1973) Periodic hematopoiesis in human cyclic neutropenia. Journal of Clinical Investigations, 52: 3320–3330.CrossRefGoogle ScholarPubMed
Imerslund, O. (1942) A case of cyclic agranulocytosis. Acta Paediatrica, 30: 232–250.CrossRefGoogle Scholar
Leale, M. (1910) Recurrent furunculosis in an infant showing an unusual blood picture. Journal of AmericanMedical Association, 54: 1854–1855.CrossRefGoogle Scholar
Meuret, G., Fliedner, T. M. (1974) Neutrophil and monocyte kinetics in a case of cyclic neutropenia. Blood, 43: 565–571.CrossRefGoogle Scholar
Reimann, H. A., De Berardinis, C. T. (1949) Periodic (cyclic) neutropenia, an entity; collection of 16 cases. Blood, 4: 1109–1116.CrossRefGoogle Scholar
Wright, D. G., Dale, D. C., Fauci, A. S., Wolff, S. M. (1981) Human cyclic neutropenia clinical review and long-term follow-up of patients. Medicine (Baltimore), 60: 1–13.CrossRefGoogle ScholarPubMed