Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-24T09:31:42.583Z Has data issue: false hasContentIssue false
  • English
  • Français

Well-differentiated liposarcoma of the epiglottis

Published online by Cambridge University Press:  13 February 2014

A Pajaniappane ,
J Farzan ,
D M Green  and
M De
A Pajaniappane*
Affiliation:
Department of Otolaryngology/Head and Neck SurgeryRoyal Derby Hospital, UK
J Farzan
Affiliation:
Department of Otolaryngology/Head and Neck SurgeryRoyal Derby Hospital, UK
D M Green
Affiliation:
Department of Histopathology, Royal Derby Hospital, UK
M De
Affiliation:
Department of Otolaryngology/Head and Neck SurgeryRoyal Derby Hospital, UK
*
Address for correspondence: Mr A Pajaniappane, Department of Otolaryngology/Head and Neck Surgery, Royal Derby Hospital, Uttoxeter Rd, Derby DE22 3AP, UK E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

Liposarcomas of the larynx and its sub-sites are rare. Within this group of tumours, well-differentiated liposarcomas of the epiglottis have been only sporadically reported. In view of its infrequent presentation, difficulty still exists over the diagnosis of this pathological entity, together with uncertainty over its exact accepted management.

Method:

We present the case of a well-differentiated liposarcoma of the epiglottis, and we review the associated English-language literature.

Results:

The reported patient underwent multiple attempts at surgical treatment prior to establishment of a firm diagnosis. In light of the diagnosis and other mitigating factors, a conservative approach was adopted.

Conclusion:

A high index of clinical suspicion and detailed histological analysis are required when encountering a recurrent soft tissue lesion of the larynx. In the presented case, a multidisciplinary approach and conservative management plan were adopted, based on a holistic management approach and a review of the published literature.

Keywords

EpiglottisLaryngeal NeoplasmsLiposarcoma
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 3 , March 2014 , pp. 296 - 298
Copyright
Copyright © JLO (1984) Limited 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Wenig, BM, Heffner, DK. Liposarcomas of the larynx and hypopharynx: a clinicopathologic study of eight new cases and a review of the literature. Laryngoscope 1995;105:747–56Google Scholar
2Muddaiah, A, Zaffarullah, W, Tewary, A. Recurrent well-differentiated liposarcoma of the larynx: a case report and review of the literature. Eur Arch Otorhinolaryngol 2010;267:1163–5Google Scholar
3Brauchle, RW, Farhood, AI, Pereira, KD. Well-differentiated liposarcoma of the epiglottis. J Laryngol Otol 2001;115:593–5Google Scholar
4Krausen, AS, Gall, AM, Garza, R, Spector, GJ, Ansel, DG. Liposarcoma of the larynx: a multicentric or a metastatic malignancy. Laryngoscope 1977;87:1116–24Google Scholar
5Mandell, DL, Brandwein, MS, Woo, P, Som, PM, Biller, HF, Urken, ML. Upper aerodigestive tract liposarcoma: report on four cases and literature review. Laryngoscope 1999;109:1245–52CrossRefGoogle ScholarPubMed
6Narula, A, Jefferis, AF. Squamous cell carcinoma and liposarcoma of the larynx occurring metachronously. J Laryngol Otol 1985;99:509–11CrossRefGoogle ScholarPubMed
7Kindblom, LG, Angervall, L, Jarlstedt, J. Liposarcoma of the neck: a clinicopathologic study of 4 cases. Cancer 1978;42:774–80Google Scholar
8Wenig, BM, Weiss, SW, Gnepp, DR. Laryngeal and hypopharyngeal liposarcoma. A clinicopathologic study of 10 cases with a comparison to soft-tissue counterparts. Am J Surg Pathol 1990;14:134–41Google Scholar
9Sommerville, SM, Patton, JT, Luscombe, JC, Mangham, DC, Grimer, RJ. Clinical outcomes of deep atypical lipoma of the extremities. Aust N Z J Surg 2005;75:803–6Google Scholar