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Rosai-Dorfman disease of the subglottis

Published online by Cambridge University Press:  08 March 2006

Produl Hazarika ,
Deepak Nayak ,
R. Balakrishnan ,
Harish Kundaje  and
P. Lakshmi Rao
Produl Hazarika
Affiliation:
Department of Pathology, Kasturba Medical College, Manipal, Karnataka State, India
Deepak Nayak
Affiliation:
Department of Pathology, Kasturba Medical College, Manipal, Karnataka State, India
R. Balakrishnan
Affiliation:
Department of Pathology, Kasturba Medical College, Manipal, Karnataka State, India
Harish Kundaje
Affiliation:
Department of Pathology, Kasturba Medical College, Manipal, Karnataka State, India
P. Lakshmi Rao
Affiliation:
Department of Pathology, Kasturba Medical College, Manipal, Karnataka State, India
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Abstract

A case of subglottic narrowing caused by an extranodal deposit of sinus histiocytosis in a 29-year-old man is reported. The characteristic features of Rosai-Dorfman disease, such as massive painless cervical lymphadenopathy, fever, raised erythrocyte sedimentation rate and raised white cell count, were all found to be absent. However, typical histological features, such as diffuse lymphoplasmacytic infiltrate, Russel bodies, foamy histiocytes and histiocytes with emperipoiesis, confirmed the diagnosis. Rosai-Dorfman disease is an uncommon disorder and its presentation with progressive subglottic narrowing is extremely rare. Our experience in the management of this condition is reported and the review of literature is discussed.

Keywords

Histiocytosis SinusLarynx
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 114 , Issue 12 , December 2000 , pp. 970 - 973
Copyright
Royal Society of Medicine Press Limited 2000

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