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Chondrosarcomas of the skull base and temporal bone

Published online by Cambridge University Press:  26 February 2007

L R Lustig ,
J Sciubba  and
M J Holliday
L R Lustig*
Affiliation:
Department of Otolaryngology – Head & Neck Surgery, University of California, San Francisco, California, USA
J Sciubba
Affiliation:
Department of Otolaryngology – Head & Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA.
M J Holliday
Affiliation:
Department of Otolaryngology – Head & Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA.
*
Address for correspondence: Dr Lawrence R Lustig, Associate Professor, Department of Otolaryngology – Head & Neck Surgery, 400 Parnassus Avenue, A746, Box 0342, San Francisco, CA 94143-0342, USA. E-mail: [email protected]
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Abstract

Objective:

To evaluate the clinical presentation and outcomes of treatment for patients with chondrosarcomas involving the skull base and temporal bone.

Study design:

Retrospective review.

Setting:

Tertiary medical centre.

Patients:

Cases of histologically confirmed chondrosarcoma involving the skull base and temporal bones.

Intervention:

Surgery.

Main outcome measures:

Demographic features of presenting patients; presenting symptoms and signs; surgical approach employed; use of post-operative radiation therapy; histological grade of tumour; and interval of post-operative follow up.

Results: Twelve patients were identified with chondrosarcomas involving the skull base, with post-operative follow up ranging from three to 33 years. The average age at presentation was 42 years. The most common presenting symptoms were diplopia, decreased visual acuity and headaches. Five of the 12 patients required multiple surgical procedures.

Conclusions:

Patients with chondrosarcoma involving the skull base and temporal bone may present in a variety of ways. Surgical resection, even subtotal, in combination with radiation therapy, can often provide good tumour control over many years for these rare tumours.

Keywords

Skull Base NeoplasmsChondrosarcomasOtologic Surgical Procedures
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 121 , Issue 8 , August 2007 , pp. 725 - 735
Copyright
Copyright © JLO (1984) Limited 2007

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References

1Hug, E, Slater, J. Proton radiation therapy for chordomas and chondrosarcomas of the skull base. Neurosurg Clin N Am 2000;11:627–38CrossRefGoogle ScholarPubMed
2Berkmen, Y, Blatt, E. Cranial and intracranial cartilaginous tumours. Clin Radiol 1968;19:327–33CrossRefGoogle ScholarPubMed
3Jaffe, H. Tumours and Tumourous Conditions of the Bone and Joints. Philadelphia: Lea Ferbiger, 1958;314–40Google Scholar
4Rosenberg, A, Nielsen, P, Keel, SB, Renard, LG, Fitzek, MM, Munzenrider, JE et al. Chondrosarcomas of the base of skull. Am J Surg Path 1999;23:1370–8CrossRefGoogle Scholar
5Dahlin, D, Unni, K. Giant cell tumor in bone tumors: General aspects and data on 8542 cases. In: Thomas, C, ed. Osteoblastoma, 4th edn. Springfield, Illinois: McGraw-Hill, 1986;119–40Google Scholar
6Adegbite, AB, McQueen, JD, Paine, KW, Rozdilsky, B. Primary intracranial chondrosarcoma: a report of two cases. Neurosurgery 1985;17:490–4CrossRefGoogle ScholarPubMed
7Coltrera, MD, Googe, PB, Harrist, TJ, Hyams, VJ, Schiller, AL, Goodman, ML. Chondrosarcoma of the temporal bone. Diagnosis and treatment of 13 cases and review of the literature. Cancer 1986;58:2689–963.0.CO;2-P>CrossRefGoogle ScholarPubMed
8Naufal, PM. Primary sarcomas of the temporal bone. Arch Otolaryngol 1973;98:44–50CrossRefGoogle ScholarPubMed
9Lau, DP, Wharton, SB, Antoun, NM, Bottrill, ID, Moffat, DA. Chondrosarcoma of the petrous apex. Dilemmas in diagnosis and treatment. J Laryngol Otol 1997;111:368–71CrossRefGoogle ScholarPubMed
10Seidman, MD, Nichols, RD, Raju, UB, Mehta, B, Levy, HG. Extracranial skull base chondrosarcoma. Ear Nose Throat J 1989;68:626–32, 635Google ScholarPubMed
11Burkey, BB, Hoffman, HT, Baker, SR, Thornton, AF, McClatchey, KD. Chondrosarcoma of the head and neck. Laryngoscope 1990;100:1301–5CrossRefGoogle ScholarPubMed
12Brown, E, Hug, EB, Weber, AL. Chondrosarcoma of the skull base. Neuroimaging Clin N Am 1994;4:529–41Google ScholarPubMed
13Weber, A, Brown, E, Hug, E, Liebsch, N. Cartilaginous tumors and chordomas of the cranial base. Otolaryngol Clin N Am 1995;28:453–71CrossRefGoogle ScholarPubMed
14Korten, A, ter Berg, H, Spincemaille, G, van, derLaan, R, Van, deWel, A. Intracranial chondrosarcoma: review of the literature and report of 15 cases. J Neurol Neurosurg Psychiatry 1988;65:88–92CrossRefGoogle Scholar
15Munzenrider, J, Liebsch, N, Efird, J. Chordomas and chondrosarcomas of the skull base: treatment with fractionated X-ray and proton radiotherapy. In: Johnson, J, Didolkar, M, eds. Head and Neck Cancer. New York, NY: Elsevier Science Publishers, 1993;649–54Google Scholar
16Koch, BB, Karnell, LH, Hoffman, HT, Apostolakis, LW, Robinson, RA, Zhen, W et al. National cancer database report on chondrosarcoma of the head and neck. Head Neck 2000;22:408–253.0.CO;2-H>CrossRefGoogle ScholarPubMed
17Kveton, JF, Brackmann, DE, Glasscock, ME 3rd, House, WF, Hitselberger, WE. Chondrosarcoma of the skull base. Otolaryngol Head Neck Surg 1986;94:23–32CrossRefGoogle ScholarPubMed
18Volpe, NJ, Liebsch, NJ, Munzenrider, JE, Lessell, S. Neuro-ophthalmologic findings in chordoma and chondrosarcoma of the skull base. Am J Ophthalmol 1993;115:97–104CrossRefGoogle ScholarPubMed
19Evans, HL, Ayala, AG, Romsdahl, MM. Prognostic factors in chondrosarcoma of bone: a clinicopathologic analysis with emphasis on histologic grading. Cancer 1977;1:818–313.0.CO;2-B>CrossRefGoogle Scholar
20Sheth, DS, Yasko, AW, Johnson, ME, Ayala, AG, Murray, JA, Romsdahl, MM. Chondrosarcoma of the pelvis. Prognostic factors for 67 patients treated with definitive surgery. Cancer 1996;78:745–503.0.CO;2-D>CrossRefGoogle ScholarPubMed
21Fisch, U. Infratemporal fossa approach to tumours of the temporal bone and base of the skull. J Laryngol Otol 1978;92:949–67CrossRefGoogle ScholarPubMed
22Al-Mefty, O, Fox, JL, Rifai, A, Smith, RR. A combined infratemporal and posterior fossa approach for the removal of giant glomus tumors and chondrosarcomas. Surg Neurol 1987;28:423–31CrossRefGoogle ScholarPubMed
23Blevins, NH, Jackler, RK, Kaplan, MJ, Gutin, PH. Combined transpetrosal-subtemporal craniotomy for clival tumors with extension into the posterior fossa. Laryngoscope 1995;105:975–82CrossRefGoogle ScholarPubMed
24Megerian, CA, Chiocca, EA, McKenna, MJ, Harsh, GFT, Ojemann, RG. The subtemporal-transpetrous approach for excision of petroclival tumors. Am J Otol 1996;17:773–9Google ScholarPubMed
25Sekhar, LN, Schramm, VL Jr, Jones, NF. Subtemporal-preauricular infratemporal fossa approach to large lateral and posterior cranial base neoplasms. J Neurosurg 1987;67:488–99CrossRefGoogle ScholarPubMed
26Samii, M, Ammirati, M. The combined supra-infratentorial pre-sigmoid sinus avenue to the petro-clival region. Surgical technique and clinical applications. Acta Neurochir (Wien) 1988;95:6–12CrossRefGoogle Scholar
27Lalwani, AK, Kaplan, MJ, Gutin, PH. The transsphenoethmoid approach to the sphenoid sinus and clivus. Neurosurgery 1992;31:1008–14Google Scholar
28Ammirati, M, Ma, J, Cheatham, ML, Mei, ZT, Bloch, J, Becker, DP. The mandibular swing-transcervical approach to the skull base: anatomical study. Technical note. J Neurosurg 1993;78:673–81CrossRefGoogle Scholar
29Crockard, HA, Steel, T, Plowman, N, Singh, A, Crossman, J, Revesz, T et al. A multidisciplinary team approach to skull base chondrosarcomas. J Neurosurg 2001;95:175–83CrossRefGoogle ScholarPubMed