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An unusual case of laryngeal spindle cell carcinoma metastasising to the orbit and heart

Published online by Cambridge University Press:  05 July 2007

N Mani ,
D Lowe ,
L Pope ,
H El-Daly  and
A Pfleiderer
N Mani
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Peterborough Hospitals NHS Trust, UK
D Lowe
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Peterborough Hospitals NHS Trust, UK
L Pope
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Peterborough Hospitals NHS Trust, UK
H El-Daly
Affiliation:
Department of Histopathology, Peterborough Hospitals NHS Trust, UK.
A Pfleiderer
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Peterborough Hospitals NHS Trust, UK
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Abstract

We report the first case in the world literature of laryngeal spindle cell carcinoma metastasising to the orbit. A 65-year-old woman was previously treated for T3 N0 Mx laryngeal spindle cell carcinoma, with laryngectomy and post-operative radiotherapy. Five months following this treatment, she developed proptosis, diplopia and reduced right visual acuity, secondary to an enlarging mass within the right orbit. This was biopsied, and subsequent histology confirmed a diagnosis of metastatic spindle cell carcinoma. Subsequent post-mortem examination demonstrated additional pulmonary, hepatic and cardiac metastatic disease, in the absence of any other primary tumour or locoregional disease. The radiological investigation of patients with laryngeal spindle cell carcinoma is discussed and contrasted with that of laryngeal squamous cell carcinoma.

Keywords

Larynx NeoplasmsSpindle Cell CarcinomaNeoplasm MetastasisOrbit
Type
Online Only Clinical Records
Information
The Journal of Laryngology & Otology , Volume 121 , Issue 9 , September 2007 , pp. 1 - 4 , e19
Copyright
2007 JLO (1984) Limited

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