We show that the Fibered Isomorphism Conjecture (FIC) of Farrell and Jones corresponding to the stable topological pseudoisotopy functor is true for fundamental groups of a large class of 3-manifolds. We also prove that if the FIC is true for irreducible 3-manifold groups then it is true for all 3-manifold groups. In fact, this follows from a more general result we prove, namely we show that if the FIC is true for each vertex group of a graph of groups with trivial edge groups then the FIC is true for the fundamental group of the graph of groups. This result is part of a program to prove the FIC for the fundamental group of a graph of groups where all the vertex and edge groups satisfy the FIC. A consequence of the first result gives a partial solution to a problem in the problem list of R. Kirby. We also deduce that the FIC is true for a class of virtually P D3-groups.
Another main aspect of this article is to prove the FIC for all Haken 3-manifold groups assuming that the FIC is true for B-groups. By definition a B-group contains a finite index subgroup isomorphic to the fundamental group of a compact irreducible 3-manifold with incompressible nonempty boundary so that each boundary component is of genus ≥ 2. We also prove the FIC for a large class of B-groups and moreover, using a recent result of L.E. Jones we show that the surjective part of the FIC is true for any B-group.