The present investigation is oriented towards a better understanding of the turbulent structure in the core region of fully developed and completely wall-bounded flows. In view of the already existing results concerning the bursting process in boundary layers (which are semi-bounded flows), an amplitude analysis of the Reynolds shear stress fluctuation u1u2, sorted into four quadrants of the u1, u2 plane, was carried out in a turbulent pipe flow. For the wall side of the core region, in which the correlation coefficient u1u2/u’1u’2 does not change appreciably with the distance from the wall, the structure of the Reynolds stress is found to be similar to that obtained in boundary layers: bursts, i.e. ejections of low speed fluid, make the dominant contribution to the Reynolds stress; the regions of violent Reynolds stress are small fractions of the overall flow; and the mean time interval between bursts is found to be almost constant across the flow. For the core region, the large cross-stream evolution of the correlation coefficient u1u2/u’1u’2 is associated with a new structure of the Reynolds stress induced by the completely wall-bounded nature of the flow. Very large amplitudes of u1u2 are still observed, but two distinct burst-like patterns are now identified and related to ejections originating from the two opposite halves of the flow. In addition to this interaction, a focusing effect caused by the circular section of the pipe is observed. As a result of these two effects, the mean time interval between the bursts decreases significantly in the core region and reaches a minimum on the pipe axis. Investigation of specific space-time velocity correlations reveals the possible existence of rotating structures similar to those observed at the outer edge of turbulent boundary layers. These coherent motions are found to have a scale noticeably larger than that of the bursts.