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Patients formerly prescribed triazolam: a study in general practice

Published online by Cambridge University Press:  13 June 2014

John D Holden
John D Holden*
Affiliation:
The Medical Centre, Haydock, St. Helens, WS11 OJN, United Kingdom
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Abstract

Objective: To discover whether patients who had formerly been prescribed triazolam continued to take psychotropic medication after its withdrawal. Method: 11 general practitioners provided details of the psychotropic medication of their patients who had previously been prescribed triazolam, 12 month after its withdrawal from Britain. Results: 70 of 91 patients (77%) were still taking regular hypnotics twelve months after the drug was withdrawn. Success at withdrawal was linked to lower doses of triazolam but did not depend upon age or sex. Conclusions: The withdrawal of triazolam resulted in a proportion of patients stopping hypnotics that is comparable with other interventions to reduce psychotropic consumption in general practice. Most patients continued to take hypnotics, which suggests that the withdrawal of a drug will usually lead to the substitution of a similar one when one is available.

Keywords

TriazolamBenzodiazepine withdrawalGeneral practice
Type
Original Papers
Information
Irish Journal of Psychological Medicine , Volume 11 , Issue 3 , September 1994 , pp. 120 - 122
Copyright
Copyright © Cambridge University Press 1994

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References

1. Department of Health. Benzodiazepine prescriptions in England 1980-91. Personally supplied information. Quoted with permission.Google Scholar
2. Anon. The sudden withdrawal of triazolam – reasons and consequences. Drug Ther Bull 1991; 29: 89–90.CrossRefGoogle Scholar
3.Salinsky, JV, Dore, CJ. Characteristics of long term benzodiazepine users in general practice. J R Coll Gen Pract 1987; 37: 202–4.Google ScholarPubMed
4.Cormack, MA, Owens, RG, Dewey, ME. The effect of minimal interventions by general practitioners on long-term benzodiazepine use. J R Coll Gen Pract 1989; 39: 408–11.Google ScholarPubMed
5.Morrison, JM. Audit and follow-up of chronic benzodiazepine tranquilliser use in general practice. Family Practice 1990; 7: 253–7.CrossRefGoogle Scholar
6.Morrice, A, Iliffe, S. Advising patients on their benzodiazepine use. Br J Gen Pract 1990; 40: 83.Google ScholarPubMed
7.Jones, D. Weaning elderly patients off psychotropic drugs in general practice: a randomised controlled trial. Health Trends 1990/1991; 22: 164–6.Google Scholar
8.Oswald, I. Triazolam syndrome 10 years on. Lancet 1989; 334: 451–2.CrossRefGoogle Scholar
9.Rodrigo, EK, King, MB, Williams, P. Health of long term benzodiazepine users. Br Med J 1988; 296: 603–6.CrossRefGoogle ScholarPubMed
10.Catalan, J, Gath, DH, Bond, A, et al.General practice patients on long-term psychotropic drugs: a controlled investigation. Br J Psychiatry 1988; 52: 399–405.CrossRefGoogle Scholar
11. Anon. The limited list; effects in general practice. Drug Ther Bull 1987; 25: 21–4.CrossRefGoogle Scholar
12.Hindmarch, I, Fairweather, DB, Rombaut, N. Adverse events after triazolam substitution. Lancet 1993; 341: 55.CrossRefGoogle ScholarPubMed