Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-24T17:56:48.347Z Has data issue: false hasContentIssue false

Physical impairments in cognitively impaired older people: implications for risk of falls

Published online by Cambridge University Press:  26 July 2012

Morag E. Taylor*
Affiliation:
Falls and Balance Research Group, Neuroscience Research Australia, University of New South Wales, Sydney, Australia Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
Kim Delbaere
Affiliation:
Falls and Balance Research Group, Neuroscience Research Australia, University of New South Wales, Sydney, Australia
Stephen R. Lord
Affiliation:
Falls and Balance Research Group, Neuroscience Research Australia, University of New South Wales, Sydney, Australia
A. Stefanie Mikolaizak
Affiliation:
Falls and Balance Research Group, Neuroscience Research Australia, University of New South Wales, Sydney, Australia
Jacqueline C. T. Close*
Affiliation:
Prince of Wales Clinical School, University of New South Wales, Sydney, Australia Falls and Injury Prevention Group, Neuroscience Research Australia, University of New South Wales, Sydney, Australia
*
Morag Taylor, Neuroscience Research Australia, Barker Street, Randwick, NSW, 2031, Australia. Tel: +61293991060, Fax: +61293991204, E-mail: [email protected].
Correspondence should be addressed to: Jacqueline Close, Neuroscience Research Australia, Barker Street, Randwick, NSW, 2031, Australia. Tel: +61293991055; Fax: +61293991204. E-mail: [email protected]

Abstract

Background: Cognitively impaired older people fall twice as often as their cognitively intact counterparts. There is, however, limited information on factors that increase the risk of falls in this population. This study aimed to determine whether a group of cognitively impaired older people (CIG) perform worse than a matched group of cognitively intact older people (NCIG) on a profile of physical performance and mobility tests.

Methods: One hundred and thirty-eight cognitively impaired and 276 age and gender matched cognitively intact community-dwelling older adults (>60 years) took part in the study. Participants completed a detailed physical performance battery from which composite fall risk scores were derived. Falls were measured prospectively for 12 months with monthly falls diaries, telephone calls, and by regularly contacting participants’ “person responsible.”

Results: The CIG performed worse than the NCIG in tests of reaction time, muscle strength (grip and quadriceps), balance (sway on floor, sway on foam, controlled leaning balance and near tandem standing ability), and mobility (sit to stand, timed up and go (TUG) and steps required to turn 180 degrees). The CIG had significantly higher composite fall risk scores than the NCIG and fell significantly more during follow-up (Multiple falls (2+): CIG 43%; NCIG 21%).

Conclusions: Fall risk in the CIG was significantly increased due to multiple physical impairments. Physical profiles provide a means of quantifying the extent of impairment in older people with cognitive impairment and potential direction for targeting interventions for reducing fall risk.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Allan, L. M., Ballard, C. G., Rowan, E. N. and Kenny, R. A. (2009). Incidence and prediction of falls in dementia: a prospective study in older people. PLoS ONE, 4, e5521.CrossRefGoogle ScholarPubMed
Asada, T.et al. (1996). Predictors of fall-related injuries among community-dwelling elderly people with dementia. Age and Ageing, 25, 2228.CrossRefGoogle ScholarPubMed
Baker, N. L., Cook, M. N., Arrighi, H. M. and Bullock, R. (2011). Hip fracture risk and subsequent mortality among Alzheimer's disease patients in the United Kingdom, 1988–2007. Age and Ageing, 40, 4954.CrossRefGoogle ScholarPubMed
Boyle, P. A.et al. (2007). Lower extremity motor function and disability in mild cognitive impairment. Experimental Aging Research: An International Journal Devoted to the Scientific Study of the Aging Process, 33, 355371.CrossRefGoogle ScholarPubMed
Campbell, A. J., Reinken, J., Allan, B. C. and Martinez, G. S. (1981). Falls in old age: a study of frequency and related clinical factors. Age and Ageing, 10, 264270.CrossRefGoogle ScholarPubMed
Delbaere, K., Close, J. C., Brodaty, H., Sachdev, P. and Lord, S. R. (2010). Determinants of disparities between perceived and physiological risk of falling among elderly people: cohort study. BMJ, 341, c4165.CrossRefGoogle ScholarPubMed
Gibson, M. J., Andres, R. O., Isaacs, B., Radebaugh, T. and Worm-Petersen, J. (1987). The prevention of falls in later life: a report of the Kellogg International Work Group on the Prevention of Falls by the Elderly. Danish Medical Bulletin, 34 (Suppl 4), 124.Google Scholar
Gillespie, L. D.et al. (2009). Interventions for preventing falls in older people living in the community. Cochrane Database of Systematic Reviews, 15 (2), CD007146.Google Scholar
Kwan, M. M., Lin, S. I., Chen, C. H., Close, J. C. and Lord, S. R. (2011). Sensorimotor function, balance abilities and pain influence timed up and go performance in older community-living people. Aging Clinical and Experimental Research, 23, 196201.CrossRefGoogle ScholarPubMed
Lorbach, E. R., Webster, K. E., Menz, H. B., Wittwer, J. E. and Merory, J. R. (2007). Physiological falls risk assessment in older people with Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 24, 260265.CrossRefGoogle ScholarPubMed
Lord, S. R. (1994). Predictors of nursing home placement and mortality of residents in intermediate care. Age and Ageing, 23, 499504.Google ScholarPubMed
Lord, S. R., Clark, R. D. and Webster, I. W. (1991). Physiological factors associated with falls in an elderly population. Journal of the American Geriatrics Society, 39, 11941200.CrossRefGoogle Scholar
Lord, S. R., Ward, J. A., Williams, P. and Anstey, K. J. (1993). An epidemiological study of falls in older community-dwelling women: the Randwick falls and fractures study. Australian Journal of Public Health, 17, 240245.CrossRefGoogle ScholarPubMed
Lord, S. R.et al. (1994a). Postural stability, falls and fractures in the elderly: results from the Dubbo Osteoporosis Epidemiology Study. Medical Journal of Australia, 160, 684685, 688–691.CrossRefGoogle ScholarPubMed
Lord, S. R., Ward, J. A., Williams, P. and Anstey, K. J. (1994b). Physiological factors associated with falls in older community-dwelling women. Journal of the American Geriatrics Society, 42, 11101117.CrossRefGoogle ScholarPubMed
Lord, S. R., Ward, J. A. and Williams, P. (1996). Exercise effect on dynamic stability in older women: a randomized controlled trial. Archives of Physical and Medical Rehabilitation, 77, 232236.CrossRefGoogle ScholarPubMed
Lord, S. R., Murray, S. M., Chapman, K., Munro, B. and Tiedemann, A. (2002). Sit-to-stand performance depends on sensation, speed, balance, and psychological status in addition to strength in older people. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 57, M539543.CrossRefGoogle ScholarPubMed
Lord, S. R., Menz, H. B. and Tiedemann, A. (2003). A physiological profile approach to falls risk assessment and prevention. Physical Therapy, 83, 237252.CrossRefGoogle ScholarPubMed
Lord, S. R.et al. (2005). The effect of an individualized fall prevention program on fall risk and falls in older people: a randomized, controlled trial. Journal of the American Geriatrics Society, 53, 12961304.CrossRefGoogle ScholarPubMed
Luukinen, H., Koski, K., Laippala, P. and Kivela, S. L. (1995). Predictors for recurrent falls among the home-dwelling elderly. Scandinavian Journal of Primary Health Care, 13, 294299.CrossRefGoogle ScholarPubMed
Mioshi, E., Dawson, K., Mitchell, J., Arnold, R. and Hodges, J. R. (2006). The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening. International Journal of Geriatric Psychiatry, 21, 10781085.CrossRefGoogle ScholarPubMed
Moller, J. (2002). Changing health resource demands for injury due to falls in ageing population. NSW Public Health Bulletin, 13 (2), 36.CrossRefGoogle ScholarPubMed
Panza, F.et al. (2010). Late-life depression, mild cognitive impairment, and dementia: possible continuum? American Journal of Geriatric Psychiatry, 18, 98116.CrossRefGoogle ScholarPubMed
Pettersson, A. F., Olsson, E. and Wahlund, L. O. (2005). Motor function in subjects with mild cognitive impairment and early Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 19, 299304.CrossRefGoogle ScholarPubMed
Podsiadlo, D. and Richardson, S. (1991). The timed “Up and Go”: a test of basic functional mobility for frail elderly persons. Journal of the American Geriatrics Society, 39, 142148.CrossRefGoogle ScholarPubMed
Salva, A.et al. (2012). Falls and risk factors for falls in community-dwelling adults with dementia (NutriAlz Trial). Alzheimer Disease and Associated Disorders, 26, 7480.CrossRefGoogle ScholarPubMed
Shaw, F. E.et al. (2003). Multifactorial intervention after a fall in older people with cognitive impairment and dementia presenting to the accident and emergency department: randomised controlled trial. BMJ, 326, 7375.CrossRefGoogle Scholar
Suttanon, P., Hill, K. D., Said, C. M., Logiudice, D., Lautenschlager, N. T. and Dodd, K. J. (2012). Balance and mobility dysfunction and falls risk in older people with mild to moderate Alzheimer disease. American Journal of Physical and Medical Rehabilitation, 91, 1223. doi:10.1097/PHM.0b013e31823caeea.CrossRefGoogle ScholarPubMed
Tinetti, M. E., Speechley, M. and Ginter, S. F. (1988). Risk factors for falls among elderly persons living in the community. New England Journal of Medicine, 319, 17011707.CrossRefGoogle ScholarPubMed
Waite, L. M., Broe, G. A., Grayson, D. A. and Creasey, H. (2000). Motor function and disability in the dementias. International Journal of Geriatric Psychiatry, 15, 897903.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Whitney, J. C., Lord, S. R. and Close, J. C. T. (2005). Streamlining assessment and intervention in a falls clinic using the Timed Up and Go test and physiological profile assessments. Age and Ageing, 34, 567571.CrossRefGoogle Scholar
Wimo, A. and Prince, M. (2010). World Alzheimer Report 2010: The Global Economic Impact of Dementia. Alzheimer's Disease International.Google Scholar