Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-13T01:14:02.505Z Has data issue: false hasContentIssue false

Microbes and geriatric mental health: past, present, and future

Published online by Cambridge University Press:  30 April 2021

Eleonora D. Vaccariello
Affiliation:
Department of Psychiatry, University of California San Diego, San Diego, CA, USA
Tanya T. Nguyen*
Affiliation:
Department of Psychiatry, University of California San Diego, San Diego, CA, USA Sam and Rose Stein Institute for Research on Aging, University of California San Diego, San Diego, CA, USA Veterans Affairs San Diego Healthcare System, San Diego, CA, USA

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Commentary
Copyright
© International Psychogeriatric Association 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Badal, V. D. et al. (2020). The gut microbiome, aging, and longevity: a systematic review. Nutrients, 12(12), 3759.CrossRefGoogle ScholarPubMed
Bested, A. C., Logan, A. C. and Selhub, E. M. (2013). Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part I-autointoxication revisited. Gut Pathogens, 5, doi: 10.1186/1757-4749-5-5.CrossRefGoogle Scholar
Chung, H. et al. (2009). Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Research Reviews, 8, 1830.CrossRefGoogle ScholarPubMed
Clemente, J. C. et al. (2012). The impact of the gut microbiota on human health: an integrative view. Cell, 12581270.CrossRefGoogle Scholar
Dinan, T. G., Stanton, C. and Cryan, J. F. (2013). Psychobiotics: a novel class of psychotropic. Biological Psychiatry, 74, 720726.CrossRefGoogle ScholarPubMed
De Filippis, F. et al. (2016). High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome. Gut, 65(11), 18121821.CrossRefGoogle ScholarPubMed
González-Moret, R. et al. (2020). The effect of a mindfulness-based therapy on different biomarkers among patients with inflammatory bowel disease: a randomised controlled trial. Scientific Reports, 10(1), 17.CrossRefGoogle ScholarPubMed
Klimova, B., Novotny, M. and Valis, M. (2020). The impact of nutrition and intestinal microbiome on elderly depression—a systematic review. Nutrients, 12(3), 710.CrossRefGoogle ScholarPubMed
Lee, S. M. et al. (2021). The intestinal microbiota as a predictor for antidepressant treatment outcome in geriatric depression: a prospective pilot study. International Psychogeriatrics, 34, 3345. doi: 10.1017/S1041610221000120.Google Scholar
Nguyen, T. T. et al. (2019). Gut microbiome in serious mental illnesses: a systematic review and critical evaluation. Schizophrenia Research, doi: 10.1016/j.schres.2019.08.026.Google ScholarPubMed
Nguyen, T. T. et al. (2021). Association of loneliness and wisdom with gut microbial diversity and composition: an exploratory study. Frontiers in Psychiatry, 12, 648475.CrossRefGoogle ScholarPubMed
Nguyen, T. T., Eyler, L. T. and Jeste, D. V (2018). Systemic biomarkers of accelerated aging in schizophrenia: a critical review and future directions. Schizophrenia Bulletin, 44(2), 398408.CrossRefGoogle ScholarPubMed
O’Mahony, S. M. et al. (2015). Serotonin, tryptophan metabolism and the brain-gut-microbiome axis. Behavioural Brain Research, 3248.CrossRefGoogle ScholarPubMed
Oriach, C. S. et al. (2016). Food for thought: The role of nutrition in the microbiota-gut-brain axis. Clinical Nutrition Experimental, 2538.CrossRefGoogle Scholar
Shields, G. S., Spahr, C. M. and Slavich, G. M. (2020). Psychosocial interventions and immune system function. JAMA Psychiatry, 77(10), 1031.CrossRefGoogle ScholarPubMed
Theou, O. et al. (2019). Can a prebiotic formulation reduce frailty levels in older people? Journal of Frailty & Aging, 8(1), 4852.Google ScholarPubMed
Venegas, D. P. et al. (2019). Short chain fatty acids (SCFAs) mediated gut epithelial and immune regulation and its relevance for inflammatory bowel diseases. Frontiers in Immunology, 277.Google Scholar
Weersma, R. K., Zhernakova, A. and Fu, J. (2020). Interaction between drugs and the gut microbiome. Gut, 15101519.CrossRefGoogle ScholarPubMed
Wilmanski, T. et al. (2021). Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nature Metabolism, 3, 274286. doi: 10.1038/s42255-021-00348-0.CrossRefGoogle ScholarPubMed
Yoshii, K. et al. (2019). Metabolism of dietary and microbial vitamin b family in the regulation of host immunity. Frontiers in Nutrition, 48.CrossRefGoogle Scholar