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HEALTH TECHNOLOGY PERFORMANCE ASSESSMENT: REAL-WORLD EVIDENCE FOR PUBLIC HEALTHCARE SUSTAINABILITY

Published online by Cambridge University Press:  23 June 2017

Augusto Afonso Guerra-Júnior ,
Lívia Lovato Pires de Lemos Open the ORCID record for Lívia Lovato Pires de Lemos [Opens in a new window] ,
Brian Godman ,
Marion Bennie ,
Cláudia Garcia Serpa Osorio-de-Castro ,
Juliana Alvares ,
Aine Heaney ,
Carlos Alberto Vassallo ,
Björn Wettermark  and
Gaizka Benguria-Arrate
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Augusto Afonso Guerra-Júnior
Affiliation:
SUS Collaborating Centre for Technology Assessment and Excellence in Health, Universidade Federal de Minas Gerais Department of Social Pharmacy, School of Pharmacy, Universidade Federal de Minas Gerais
Lívia Lovato Pires de Lemos
Affiliation:
SUS Collaborating Centre for Technology Assessment and Excellence in Health, Universidade Federal de Minas Gerais Post-Graduation Program in Public Health, School of Medicine, Universidade Federal de Minas [email protected]
Brian Godman
Affiliation:
Strathclyde Institute of Pharmacy and Biomedical Sciences, Strathclyde University Division of Clinical Pharmacology, Karolinska University Hospital Huddinge, Karolinska Institutet
Marion Bennie
Affiliation:
Strathclyde Institute of Pharmacy and Biomedical Sciences, Strathclyde University
Cláudia Garcia Serpa Osorio-de-Castro
Affiliation:
Sergio Arouca National School of Public Health, Fundação Oswaldo Cruz
Juliana Alvares
Affiliation:
SUS Collaborating Centre for Technology Assessment and Excellence in Health, Universidade Federal de Minas Gerais Department of Social Pharmacy, School of Pharmacy, Universidade Federal de Minas Gerais
Aine Heaney
Affiliation:
National Prescribing Service Medicinewise
Carlos Alberto Vassallo
Affiliation:
Facultad de Ciencias Médicas, Universidad Nacional del Litoral
Björn Wettermark
Affiliation:
Public Healthcare Services Committee, Department of Healthcare Development, Stockholm County Council Department of Medicine Solna, Clinical Epidemiology/Clinical pharmacology, Karolinska Institutet and Karolinska University Hospital
Gaizka Benguria-Arrate
Affiliation:
Osteba, Basque Office for HTA Ministry for Health, Basque Government
Iñaki Gutierrez-Ibarluzea
Affiliation:
Osteba, Basque Office for HTA Ministry for Health, Basque Government
Vania Cristina Canuto Santos
Affiliation:
Department of Management and Incorporation of Technologies, Brazilian Ministry of Health
Clarice Alegre Petramale
Affiliation:
Department of Management and Incorporation of Technologies, Brazilian Ministry of Health
Fransciso de Assis Acurcio
Affiliation:
SUS Collaborating Centre for Technology Assessment and Excellence in Health, Universidade Federal de Minas Gerais Department of Social Pharmacy, School of Pharmacy, Universidade Federal de Minas Gerais For the CCATES team
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Abstract

Objectives: Health technology financing is often based on randomized controlled trials (RCTs), which are often the same ones used for licensing. Because they are designed to show the best possible results, typically Phase III studies are conducted under ideal and highly controlled conditions. Consequently, it is not surprising that technologies do not always perform in real life in the same way as controlled conditions. Because financing (and price paid) decisions can be made with overestimated results, health authorities need to ask whether health systems achieve the results they expect when they choose to pay for a technology. The optimal way to answer this question is to assess the performance of financed technologies in real-world settings. Health technology performance assessment (HTpA) refers to the systematic evaluation of the properties, effects, and/or impact of a health intervention or health technology in the real world to provide information for investment/disinvestment decisions and clinical guideline updates. The objective is to describe the development and principal aspects of the Guideline for HTpA commissioned by the Brazilian Ministry of Health.

Methods: Our methods used include extensive literature review, refinement with experts across countries, and public consultation.

Results: A comprehensive guideline was developed, which has been adopted by the Brazilian government.

Conclusion: We believe the guideline, with its particular focus on disinvestment, along with the creation of a specific program for HTpA, will allow the institutionalization and continuous improvement of the scientific methods to use real-world evidence to optimize available resources not only in Brazil but across countries.

Keywords

Technology assessmentBiomedicalObservational studiesHealth policyHealth information systems
Type
Policies
Information
International Journal of Technology Assessment in Health Care , Volume 33 , Issue 2 , 2017 , pp. 279 - 287
Copyright
Copyright © Cambridge University Press 2017 

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