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Tuberculin Testing in a Tertiary Hospital: Product Variability

Published online by Cambridge University Press:  02 January 2015

Joseph W. Shands Jr ,
Deborah Boeff ,
Loretta Fauerbach  and
Richard R. Gutekunst
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Abstract

Nine percent of 2,721 hospital employees, previously tuberculin negative, were PPD positive when tested with 5 TU of PPD (Aplisol, Parke-Davis). Seventy percent of the positive reactions were found to be erroneous on retesting with Tubersol (Connaught). The excessive potency of Aplisol led to excessive expenditures of time and money investigating a nonexistent outbreak.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 15 , Issue 12 , December 1994 , pp. 758 - 760
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1994

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References

1. Comstock, GW. False tuberculin test results. Chest 1975:68(Suppl):465.CrossRefGoogle ScholarPubMed
2. Chaparas, SD, Vandiviere, HM, Melvin, I, Koch, G, Becker, C. Tuberculin test: variability with the Mantoux procedure. Am Rev Respir Dis 1985;132:175–177.Google Scholar
3. McCarter, JR Watson, DR. The relationship of the antigenicity, physico-chemical properties, and the polysaccharide content of tuberculins to their intracutaneous activity J Immunol 1942;43:85–98.Google Scholar
4. Raad, I, Cusick, J, Sherertz, RJ, Sabbagh, M. Howell, N. Annual tuberculin skin testing of employees at a university hospital: a cost benefit analysis. Infect Control Hosp Epidemiol 1989;10:465–469.Google Scholar
5. Thompson, NJ, Glassmth, JL, Snider, DE Jr, Farer, LS. The booster phenomenon in serial tuberculin testing. Am Rev Respir Dis 1979;119:587–597.Google Scholar
6. Blackshear, J, Bravo, E, Gesink, D, Davies, SE Iber, C, Johnson, JR. False positive tests with Parke-Davis Aplisol. Am Rev Respir Dis 1983;127:254.Google Scholar
7. Hospital Employee Health 1993;12:89–93.Google Scholar
8. Lanphear, BP, Linnemann, CC, Cannon, CG. A high false-positive rate of tuberculosis associated with Aplisol: an investigation among health care workers. J Infect Dis 1994;169:703–704.Google Scholar
9. Lifson, AR Watters, JK, Thompson, S, Crane, CM, Wise, E. Discrepancies in tuberculin skin test results with two commercial products in a population of intravenous drug users. J Infect Dis 1993;168:1048–1051.Google Scholar