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Topical Mupirocin for Eradication of MRSA Colonization With Mupirocin-Resistant Strains

Published online by Cambridge University Press:  02 January 2015

Makeda Semret  and
Mark A. Miller
Makeda Semret
Affiliation:
Infection Prevention and Control Unit and Department of Microbiology, SMBD-Jewish General Hospital, Montreal, Quebec, Canada
Mark A. Miller*
Affiliation:
Infection Prevention and Control Unit and Department of Microbiology, SMBD-Jewish General Hospital, Montreal, Quebec, Canada
*
Department of Microbiology, SMBD-Jewish General Hospital, 3755 Cote Ste Catherine Rd, Montreal, Quebec H3T1E2, Canada
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Abstract

Topical mupirocin was able to interrupt colonization of 52% and 68% of methicillin-resistant Staphylococcus aureus (MRSA)-colonized patients carrying mupirocin-resistant and -sensitive strains, respectively, including 44.4% and 85.7% of those colonized only in the nares. Although a trend to decreased effectiveness was seen for clearing mupirocin-resistant MRSA this agent can decolonize many patients with resistant strains.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 22 , Issue 9 , September 2001 , pp. 578 - 580
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2001

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