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Spread of Methicillin-Resistant Staphylococcus aureus (MRSA) Among Household Contacts of Individuals With Nosocomially Acquired MRSA

Published online by Cambridge University Press:  02 January 2015

David P. Calfee ,
Lisa J. Durbin ,
Teresa P. Germanson ,
Denise M. Toney ,
Elise B. Smith  and
Barry M. Farr
David P. Calfee*
Affiliation:
Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia
Lisa J. Durbin
Affiliation:
Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia
Teresa P. Germanson
Affiliation:
Germanson and Associates, LLC, Charlottesville, Virginia
Denise M. Toney
Affiliation:
Commonwealth of Virginia Department of General Services, Division of Consolidated Laboratory Services, Richmond, Virginia
Elise B. Smith
Affiliation:
Commonwealth of Virginia Department of General Services, Division of Consolidated Laboratory Services, Richmond, Virginia
Barry M. Farr
Affiliation:
Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia
*
Box 801337, University of Virginia Health System, Charlottesville, VA 22908
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Abstract

Objective:

To determine the frequency with which methicillin-resistant Staphylococcus aureus (MRSA) is spread from colonized or infected patients to their household and community contacts.

Design:

Retrospective cohort study.

Setting:

University hospital.

Participants:

Household and community contacts of MRSA-colonized or -infected patients for whom MRSA screening cultures were performed.

Results:

MRSA was isolated from 25 (14.5%) of 172 individuals. Among the contacts of index patients who had at least one MRSA-colonized contact, those with close contact to the index patient were 7.5 times more likely to be colonized (53% vs 7%; 95% confidence interval, 1.1 to 50.3; P = .002). An analysis of antimicrobial susceptibility and DNA fingerprint patterns suggested person-to-person spread.

Conclusions:

MRSA colonization occurs frequently among household and community contacts of patients with nosocomially acquired MRSA, suggesting that transmission of nosocomially acquired MRSA outside of the healthcare setting may be a substantial source of MRSA colonization and infection in the community.

Type
Orginal Articles
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 6 , June 2003 , pp. 422 - 426
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

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