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Outbreak of Nosocomial Burkholderia cepacia Infection and Colonization Associated With Intrinsically Contaminated Mouthwash

Published online by Cambridge University Press:  02 January 2015

Linda Matrician ,
Gretehen Ange ,
Sonia Burns ,
W. Lee Fanning ,
Clare Kioski ,
Gary D. Cage  and
Kenneth K. Komatsu
Linda Matrician
Affiliation:
Scottsdale Healthcare Infection Control Department, Scottsdale
Gretehen Ange
Affiliation:
Scottsdale Healthcare Infection Control Department, Scottsdale
Sonia Burns*
Affiliation:
Scottsdale Healthcare Infection Control Department, Scottsdale
W. Lee Fanning
Affiliation:
Scottsdale Healthcare Infection Control Department, Scottsdale
Clare Kioski
Affiliation:
Infectious Disease Epidemiology and Clinical Microbiology Section, Arizona Department of Health Services, Phoenix, Arizona
Gary D. Cage
Affiliation:
Infectious Disease Epidemiology and Clinical Microbiology Section, Arizona Department of Health Services, Phoenix, Arizona
Kenneth K. Komatsu
Affiliation:
Infectious Disease Epidemiology and Clinical Microbiology Section, Arizona Department of Health Services, Phoenix, Arizona
*
Scottsdale Healthcare Infection Control, 3634 N Civic Center Blvd, Scottsdale, AZ 85251
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Abstract

From August 1996 through June 1998, 69 ventilated, intensive care unit patients at two Arizona hospitals had nosocomial respiratory tract cultures positive for Burkholderia cepacia. Intrinsically contaminated alcohol-free mouthwash was identified by pulsed-field gel electrophoresis as the source of the outbreak

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 21 , Issue 11 , November 2000 , pp. 739 - 741
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2000

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References

1.Gilardi, GL. Pseudomonas aud Burkholderia. In: Murry, PR, Baron, EJ, Pfaller, MA, Tenover, FC, Yolken, RH, eds. Manual of Clinical Microbiology. 6th ed. Washington, DC: ASM Press; 1995:509–519.Google Scholar
2.Goldmann, DA, Klinger, JD. Pseudomonas cepacia: biology, mechanisms of virulence, epidemiology. J Pediatr 1986;108:806–812.Google Scholar
3.Bernstein, B, Dineen, T, Kehl, S, Wilson, P, Sohnle, P. Outbreak of Burkholderia cepacia colonization and infection related to contaminated mouthwash. Am J Med 1982;73:183–186.Google Scholar
4.Garner, JS, Jarvis, WREmori, TG, Horan, TC, Hughes, JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128–140.Google Scholar
5.Martone, WJ, Tablan, OC, Jarvis, WRThe epidemiology of nosocomial epidemic Pseudomonas cepacia infections. Eur J Epidemiol 1987;3:222–232.Google Scholar
6.Panlilio, AL, Beck-Sague, CM, Siegel, JD, Anderson, RL, Yetts, SY, Clark, NC, et al.Infections and pseudoinfections due to povidone-iodine solution contaminated with Pseudomonas cepacia. Clin Infect Dis 1992;14:1078–1083.CrossRefGoogle ScholarPubMed
7.Hutchinson, GRParker, S, Pryor, JA, Duncan-Skingle, F, Hoffman, PN, Hodson, ME, et al. Home-use nebulizers: a potential primary source of Burkholderia cepacia and other colistin-resistant, gram-negative bacteria in patients with cystic fibrosis. J Clin Microbiol 1996;34:584–587.Google Scholar
8.Reboli, AC, Koshinski, RArias, K, Marks-Austin, K, Stieritz, D, Stull, TLAn outbreak of Burkholderia cepacia lower respiratory tract infection associated with contaminated albuterol nebulization solution. Infect Control Hosp Epidemiol 1996;17:741–743.Google Scholar
9.LiPuma, JJ, Dasen, TD, Nielson, DW, Stern, RC, Stall, TL. Person to person transmission of Pseudomonas cepacia between patients with cystic fibrosis. Lancet 1990;336:1094–1096.Google Scholar
10.Kurtzweil, P. Alcohol-free mouthwash with twist of bacteria. FDA Consumer. 1996; Oct. Available from: http://www.fda.gov/fdac/departs/896_irs.html (last article on the page).Google Scholar
11.FDA Enforcement Report. August 24, 1994. Available from: http://www.fda.gov//bbs/topics/ENFORCE/ENF00332.html.Google Scholar
12.FDA Enforcement Report. May 15, 1996. Available from: http://www.fda.gov//bbs/topics/ENFORCE/ENF00433.html.Google Scholar
13.Tablan, OC, Anderson, IJ, Arden, NH, Breiman, RF, Butler, JC, McNeil, MM. Guidelines for Prevention of Nosocomial Pneumonia. The Hospital Infection Control Practices Advisory Committee, Centers for Disease Control and Prevention. Infect Control Hosp Epidemiol 1994;15:587–627.Google Scholar