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Multidrug Resistance among Gram-Negative Pathogens That Caused Healthcare-Associated Infections Reported to the National Healthcare Safety Network, 2006–2008

Published online by Cambridge University Press:  02 January 2015

Alexander J. Kallen ,
Alicia I. Hidron ,
Jean Patel  and
Arjun Srinivasan
Alexander J. Kallen*
Affiliation:
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Alicia I. Hidron
Affiliation:
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia
Jean Patel
Affiliation:
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Arjun Srinivasan
Affiliation:
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
*
1600 Clifton Rd NE, MS A-35, Atlanta, Georgia30333, ([email protected])
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Abstract

We evaluated isolates of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii that were reported to the National Healthcare Safety Network from January 2006 through December 2008 to determine the proportion that represented multidrug-resistant phenotypes. The pooled mean percentage of resistance varied by the definition used; however, multidrug resistance was relatively common and widespread.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 31 , Issue 5 , May 2010 , pp. 528 - 531
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

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References

1.Maragakis, LL, Cosgrove, SE, Song, X, et al.An outbreak of multidrug-resistant Acinetobacter baumannii associated with pulsatile lavage wound treatment. JAMA 2004;292:3006–3011.CrossRefGoogle ScholarPubMed
2.Lolans, K, Rice, TW, Munoz-Price, LS, Quinn, JRMulti-city outbreak of carbapenem-resistant Acinetobacter baumannii isolates producing the carbapenemase OXA-40. Antimicrob Agents Chemother 2006;50:2941–2945.CrossRefGoogle Scholar
3.Woodford, N, Tierno, PM Jr, Young, K, et al.Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A β-lacta-mase, KPC-3, in a New York medical center. Antimicrob Agents Chemother 2004;48:4793–4799.CrossRefGoogle Scholar
4.Bratu, S, Landman, D, Haag, R, et al.Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium. Arch Intern Med 2005;165:1430–1435.CrossRefGoogle ScholarPubMed
5.Karlowsky, JA, Draghi, DC, Jones, ME, Thornsberry, C, Friedland, IR, Sahm, DF. Surveillance for antimicrobial susceptibility among clinical isolates of Pseudomonas aeruginosa and Acinetobacter baumannii from hospitalized patients in the United States, 1998-2001. Antimicrob Agents Chemother 2003;47:1681–1688.CrossRefGoogle Scholar
6.Obritsch, MD, Fish, DN, McLaren, R, Jung, R. National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002. Antimicrob Agents Chemother 2004;48:4606–4610.CrossRefGoogle ScholarPubMed
7. US Census Bureau. Census Regions and Divisions of the United States. http://www.census.gov/geo/www/us_regdiv.pdf. Accessed September 28, 2009.Google Scholar
8.Hidron, AI, Edwards, JE, Patel, J, et al.Antimicrobial-resistant pathogens associated with healthcare-associated infections: annual survey of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007. Infect Control Hosp Epidemiol 2008;29:996–1011.Google Scholar
9.Falagas, ME, Karageorgopoulos, DE. Pandrug resistance, extensive drug resistance, and multidrug resistance among gram-negative bacilli: need for international harmonization in terminology. Clin Infect Dis 2008;46:1121–1122.Google Scholar
10. Management of multidrug-resistant organisms in healthcare settings, 2006. Healthcare Infection Control Practices Advisory Committee, http://www.cdc.gov/ncidod/dhqp/pdf/ar/mdroGuideline2006.pdf. Accessed August 4, 2009.Google Scholar
11.Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. MMWR 2009;58:256–260.Google Scholar