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Mortality Attributable to Nosocomial Infections in the ICU

Published online by Cambridge University Press:  02 January 2015

Jean-Yves Fagon ,
Ana Novara ,
François Stephan ,
Emmanuelle Girou  and
Michel Safar
Jean-Yves Fagon*
Affiliation:
Service de Réanimation Médicale, Hôpital Broussais, Paris, France
Ana Novara
Affiliation:
Service de Réanimation Médicale, Hôpital Broussais, Paris, France
François Stephan
Affiliation:
Service de Réanimation Médicale, Hôpital Broussais, Paris, France
Emmanuelle Girou
Affiliation:
Service de Réanimation Médicale, Hôpital Broussais, Paris, France
Michel Safar
Affiliation:
Service de Réanimation Médicale, Hôpital Broussais, Paris, France
*
Service de Réanimation Médicale, Hôpital Broussais, 96 rue Didot, 75014 Paris, France
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Abstract

Although a direct relationship between nosocomial infection and mortality in intensive care unit (ICU) patients has not always been demonstrated formally, it is possible to conclude that nosocomial infections increase the risk of death in critically ill patients. A more precise analysis indicates that: 1) this effect is highly probable for pneumonia, doubtful for bacteremia, and uncertain for urinary tract infection; 2) risk increases with duration of stay in the ICU; 3) bacterial etiology modifies the risk; and 4) this effect is stronger in less severely ill patients, probably because the severity of underlying disease remains the most significant factor.

Type
From the Third International Conference on the Prevention of Infection
Information
Infection Control & Hospital Epidemiology , Volume 15 , Issue 7 , July 1994 , pp. 428 - 434
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1994

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