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Factors Influencing Field Testing of Alcohol-Based Hand Rubs

Published online by Cambridge University Press:  29 December 2014

Raphaële Girard ,
Emmanuelle Carre ,
Valérie Mermet ,
Crespin C. Adjide ,
Sylviane Blaise ,
Monique Dagain ,
Christine Debeuret ,
Stéphane Delande ,
Valérie Dubois  and
Pascal Fascia
...Show all authors
Raphaële Girard*
Affiliation:
Nosocomial Infection Department Hospices Civils de Lyon, Lyon, France
Emmanuelle Carre
Affiliation:
Pharmacy Hospices Civils de Lyon, Lyon, France
Valérie Mermet
Affiliation:
Pharmacy Hospices Civils de Lyon, Lyon, France
Crespin C. Adjide
Affiliation:
Nosocomial Infection Department CHU Amiens, Amiens, France
Sylviane Blaise
Affiliation:
Nosocomial Infection Department CH Belfort Montbelliard, Belfort, France
Monique Dagain
Affiliation:
Economic Department CHU Dijon, Dijon, France
Christine Debeuret
Affiliation:
Pharmacy Assistance Publique des Hopitaux de Marseille, Marseille, France
Stéphane Delande
Affiliation:
Economic Department CH Dieppe, Dieppe, France
Valérie Dubois
Affiliation:
Pharmacy CHU Saint Etienne, Saint Etienne, France
Pascal Fascia
Affiliation:
Nosocomial Infection Department CHU Saint Etienne, Saint Etienne, France
Caroline Hadjadj
Affiliation:
Pharmacy CHU Bordeaux, Bordeaux, France
Marianne Honnart
Affiliation:
Economic Department CHU Dijon, Dijon, France
Christelle Labrande
Affiliation:
Pharmacy Assistance Publique des Hopitaux de Marseille, Marseille, France
Agnès Lasheras Bauduin
Affiliation:
Nosocomial Infection Department CHU Bordeaux, Bordeaux, France
Adeline Martin
Affiliation:
Economic Department CHU Amiens, Amiens, France
Françoise Petiteau Moreau
Affiliation:
Pharmacy CHU Bordeaux, Bordeaux, France
Nicole Roattino
Affiliation:
Nosocomial Infection Department Assistance Publique des Hopitaux de Marseille, Marseille, France
Estelle Rougeot
Affiliation:
Pharmacy CH Belfort Montbelliard, Belfort, France
Jacqueline Shum Cheong Sing
Affiliation:
Nosocomial Infection Department CHU Grenoble, Grenoble, France
Martine Urban
Affiliation:
Pharmacy CHU Angers, Angers, France
Marie Laure Valdeyron
Affiliation:
Nosocomial Infection Department Hospices Civils de Lyon, Lyon, France
*
Address correspondence to Raphaële Girard, MD, Unité d’Hygiène et Epidémiologie, Bâtiment 3B, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 69495 Pierre Bénite CEDEX France ([email protected]).
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Abstract

BACKGROUND

According to the World Health Organization guidelines, field tests, in the context of a bid for the supply of alcohol-based hand rubs, should take into account climatic region, test period, products already in use, and type of use (hygienic or surgical) when assessing tolerance. This laborious method is often contested.

OBJECTIVE

To conduct a post hoc analysis of the data of a large bid, including 5 factors, to validate the relevance of their inclusion.

METHODS

For the purposes of the bid, products were compared in terms of the 4 World Health Organization tolerance criteria (appearance, intactness, moisture content, sensation) during product testing and were separated into groups on the basis of the studied factors. The post hoc analysis method included (1) comparison of the mean before-and-after difference based on the self-evaluation of the skin with the 4 World Health Organization tolerance criteria, between climatic regions, periods, products in use, test product, and the type of use; (2) generalized linear models, taking into account all studied factors.

RESULTS

The analysis included data for 1,925 pairs of professionals. The means of the differences observed were independently and significantly associated with the test period (P<.001), the hygienic or surgical use (P=.010 to .041, not significant for appearance), the product already in use (significant for appearance P=.021), and the test product (P<.001). The association with climatic region was found to be significant only in the nonadjusted analysis.

CONCLUSION

The type of use, the test period, and the product in use should be taken into account when designing field tests of alcohol-based hand rubs.

Infect Control Hosp Epidemiol 2014;00(0): 1–9

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 36 , Issue 3 , March 2015 , pp. 302 - 310
Copyright
© 2014 by The Society for Healthcare Epidemiology of America. All rights reserved 

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