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Enterobacter Sepsis in Infants and Children Due to Contaminated Intravenous Fluids

Published online by Cambridge University Press:  02 January 2015

Nikos S. Matsaniotis ,
Vassiliki Ph. Syriopoulou ,
Maria Ch. Theodoridou ,
Konstantina G. Tzanetou  and
Glyceria I. Mostrou
Nikos S. Matsaniotis*
Affiliation:
A' Department of Pediatrics, Athens University “Aghia Sophia” Children's Hospital, Athens, Greece
Vassiliki Ph. Syriopoulou
Affiliation:
A' Department of Pediatrics, Athens University “Aghia Sophia” Children's Hospital, Athens, Greece
Maria Ch. Theodoridou
Affiliation:
A' Department of Pediatrics, Athens University “Aghia Sophia” Children's Hospital, Athens, Greece
Konstantina G. Tzanetou
Affiliation:
A' Department of Pediatrics, Athens University “Aghia Sophia” Children's Hospital, Athens, Greece
Glyceria I. Mostrou
Affiliation:
A' Department of Pediatrics, Athens University “Aghia Sophia” Children's Hospital, Athens, Greece
*
Athens University, “Aghia Sophia” Children's Hospital, Athens, 115, 27, Greece
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Abstract

Sixty-three cases of nosocomial sepsis occurring from April through October 1981, in a 500-bed pediatric hospital, were traced to bacterial contamination of intravenous fluid produced by a single manufacturer. Two species of uncommon blood stream pathogens, Enterobacter cloacae and Enterobacter agglomerans contaminated the fluid. Infections with these organisms might have contributed to the death of four patients; two who were immunosuppressed, one who was asplenic and one premature infant. Epidemiologic and laboratory investigations identified the site of contamination to be within the screw-caps of the bottles containing the intravenous fluid. Contamination occurred during insertion of the intravenous fluid administration set into the bottle. The “epidemic” terminated when the hospital discontinued the use of infusion fluids from that manufacturer. We conclude that intravenous fluids should be examined during outbreaks of nosocomial bacteremia due to unusual pathogens.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 5 , Issue 10 , October 1984 , pp. 471 - 477
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1984

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