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Aztreonam

Published online by Cambridge University Press:  21 June 2016

Allan R. Tunkel
Allan R. Tunkel*
Affiliation:
Departments of Internal Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
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Extract

Aztreonam, the first licensed monobactam in the United States, is a β-lactam antimicrobial agent with a unique structure and in vitro spectrum of activity. The drug is active only against gram-negative aerobic bacteria in vitro, thus resembling the spectrum of aminoglycosides, but displays the safety profile typical of β-lactam agents. Due to these properties, aztreonam may prove useful in the therapy of various nosocomial infections. This review outlines the salient features of aztreonam and suggests areas of appropriate usage.

Type
Special Section
Information
Infection Control & Hospital Epidemiology , Volume 11 , Issue 9 , September 1990 , pp. 486 - 494
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1990

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