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The Utility of Polysporin Ointment in the Eradication of Methicillin-Resistant Staphylococcus aureus Colonization: A Pilot Study

Published online by Cambridge University Press:  02 January 2015

Scott Fung ,
Sharon O'Grady ,
Catharine Kennedy ,
Helen Dedier ,
Iivi Campbell  and
John Conly
Scott Fung
Affiliation:
Division of Infectious Diseases, Department of Medicine, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada
Sharon O'Grady
Affiliation:
Infection Control Unit, the Riverdale Hospital, Toronto, Ontario, Canada
Catharine Kennedy
Affiliation:
Infection Prevention and Control Unit, University Health Network, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada
Helen Dedier
Affiliation:
Department of Microbiology, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada
Iivi Campbell
Affiliation:
Department of Microbiology, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada
John Conly*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada Department of Microbiology, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada Infection Prevention and Control Unit, University Health Network, Toronto General and Toronto Western Hospitals, University of Toronto, Ontario, Canada Infection Control Unit, the Riverdale Hospital, Toronto, Ontario, Canada
*
Hospital Epidemiologist, University Health Network, 13 NU-118, Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada
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Abstract

We evaluated the efficacy of an ointment containing bacitracin, polymyxin B, and gramicidin for the eradication of colonization by methicillin-resistant Staphylococcus aureus in 11 medical patients, 10 (91%) of whom had previously failed a 1-week course of topical mupirocin. Mupirocin resistance was documented in 5 (45%) of 11 patients. Successful decolonization was achieved in 9 (82%) of 11 patients (based on 2 months of follow-up).

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 21 , Issue 10 , October 2000 , pp. 653 - 655
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2000

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