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Investigation of Mediastinitis Due to Coagulase-Negative Staphylococci After Cardiothoracic Surgery

Published online by Cambridge University Press:  21 June 2016

Maria D. Van Kerkhove*
Affiliation:
Department of Health, Research, and Policy, Stanford University Medical Center, Stanford, California Exponent Health Sciences Practice, New York, New York
Julie Parsonnet
Affiliation:
Department of Health, Research, and Policy, Stanford University Medical Center, Stanford, California Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University Medical Center, Stanford, California
Michal Weingart
Affiliation:
Exponent Health Sciences Practice, Oakland, California
Lucy S. Tompkins
Affiliation:
Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University Medical Center, Stanford, California
*
Exponent Health Sciences Practice, 420 Lexington Avenue, Suite 1740, New York, New York 10170 ([email protected])

Abstract

Six cases of coagulase-negative staphylococcal mediastinitis were identified in the latter half of 1999. A new preoperative cleansing solution was suspected by hospital staff to be a factor in the outbreak. We evaluated this possible risk factor along with other known and suspected surgical site infection risk factors in this case-control study.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

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References

1.Pfaller, MA. Chromosomal restriction fragment analysis by pulsed-field gel electrophoresis—application to molecular epidemiology. In: Isenberg, HD, ed. Essential Procedures for Clinical Microbiology. ASM Press, Washington, DC; 1998:651657.Google Scholar
2.Horan, TC, Gaynes, RP, Martone, WJ, Jarvis, WR, Emori, TG. CDC definitions of nosocomial surgical site infections, 1992, a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992; 13:606608.Google Scholar
3.Tenover, FC, Arbeit, RD, Goering, RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33:22332239.Google Scholar
4.Tenover, FC, Arbeit, RD, Goering, RV. How to select and interpret molecular strain typing methods for epidemiological studies of bacterial infections: a review for healthcare epidemiologists. The Molecular Working Group of the Society For Healthcare Epidemiology of America. Infect Control Hosp Epidemiol 1997; 18:426439.Google Scholar
5.Farinas, MC, Gald Peralta, F, Bernal, JM, Rabasa, JM, Revuelta, JM, Gonzalez-Mecias, J. Suppurative mediastinitis after open-heart surgery: a case-control study covering a seven-year period in Santander, Spain. Clin Infect Dis 1995; 20:272279.Google Scholar
6.Mayhall, CG, ed. Hospital Epidemiology and Infection Control. 3rd ed. Baltimore, MD: Williams & Wilkins; 2004.Google Scholar
7.Roy, MC. Surgical site infections after coronary artery bypass graft surgery: discriminating site-specific risk factors to improve prevention efforts. Infect Control Hosp Epidemiol 1998; 19:229233.Google Scholar
8.Mangram, AJ, Horan, TC, Pearson, ML, Silver, LC, Jarvis, WR. Guideline for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol 1999; 20:250278.Google Scholar
9.Gummert, JF, Barten, MJ, Hans, C, et al. Mediastinitis and cardiac surgery—an updated risk factor analysis in 10,373 consecutive adult patients. Thorac Cardiovasc Surg 2002; 50:8791.Google Scholar
10.Abboud, CS, Wey, SB, Baltar, VT. Risk factors for mediastinitis after cardiac surgery. Ann Thorac Surg 2004; 77:676683.CrossRefGoogle ScholarPubMed
11.Abid, Q, Nkere, UU, Hasan, A, et al. Mediastinitis in heart and lung transplantation: 15 years experience. Ann Thorac Surg 2003; 75:15651571.Google Scholar
12.Baldwin, RT, Radovancevis, B, Sweeney, MS, Duncan, JM, Frazier, OH. Bacterial infection after heart transplantation. J Heart Lung Transplant 1992; 11:545549.Google ScholarPubMed
13.NNIS System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2003, issued August 2003. Am J Infect Control 2003; 31:481498.Google Scholar
14.SAS [computer program]. Version 9.0 (TS M0). Cary, NC: SAS Institute; 2002.Google Scholar