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Infection with Methicillin-Resistant Staphylococcus aureus Among Hospital Employees

Published online by Cambridge University Press:  21 June 2016

Robert R. Muder ,
Carole Brennen  and
Angella M. Goetz
Robert R. Muder*
Affiliation:
Veterans Affairs Medical Center and Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Annsylvania
Carole Brennen
Affiliation:
Veterans Affairs Medical Center and Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Annsylvania
Angella M. Goetz
Affiliation:
Veterans Affairs Medical Center and Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Annsylvania
*
Infectious Disease Section, VA Medical Center, University Drive C, Pittsburgh, PA 15240
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Abstract

Objective:

To describe the spectrum of clinical infection caused bymethicillin-resistant Staphylococcus aureus (MRSA) in healthcare workers.

Design:

Case series.

Setting:

Two Veterans Affairs hospitals in which methicillin-resistant S aureus (MRSA) is endemic.

Patients:

Five employees presenting to employee health or infectious disease clinic.

Results:

All employees had had direct exposure to patients colonized with MRSA. Employee infections included cellulitis, impetigo, folliculitis, paronychia, and conjunctivitis. MRSA was isolated from all clinically infected sites and from the anterior nares of two employees. Three employees received a variety of ineffective oral antimicrobials before MRSA was recognized as the causative agent. All infections responded to appropriate therapy.

Conclusions:

Employees of hospitals with endemic MRSA may acquire MRSA infection. Presentation in our employees was that of relatively uncomplicated soft tissue infection, but several employees received inappropriate therapy before bacteriologic diagnosis. We recommend that culture and susceptibility testing be obtained prior to institution of therapy when hospital employees present with soft tissue infection.

Type
Brief Report
Information
Infection Control & Hospital Epidemiology , Volume 14 , Issue 10 , October 1993 , pp. 576 - 578
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1993 

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References

1. Haley, RW, Hightower, AW, Khabbaz, RF, et al. The emergence of methicillin-resistant Staphylococcus aureus infections in United States hospitals: possible role of the house-staff patient transfer circuit. Ann Intern Med 1982;97:297–308.10.7326/0003-4819-97-3-297CrossRefGoogle ScholarPubMed
2. Klimek, JJ, Marsik, FJ, Bartlett, RC, et al. Clinical, epidemiologic and bacteriologic observations of an outbreak of methicillin-resistant Staphylococcus aureus at a large community hospital. Am J Med 1976;61:340–345.10.1016/0002-9343(76)90370-3CrossRefGoogle Scholar
3. Boyce, JM, Landry, M, Deetz, TR, Dupont, HL. Epidemiologie studies of an outbreak of nosocomial methicillin-resistant Staphy-Zococcus aureus infections. Infect Control 1981;2:110–116.10.1017/S0195941700053881CrossRefGoogle Scholar
4. Craven, DE, Reed, C, Kollisch, N, et al. A large outbreak of infections caused by a strain of Staphylococcus aureus resistant to oxacillin and aminoglycosides. Am J Med 1981;71:53–58.10.1016/0002-9343(81)90258-8CrossRefGoogle ScholarPubMed
5. Cookson, B, Peters, B, Webster, M. et al. Staff carriage of epidemicmethicillin-resistant Staphylococcus aureus . J Clin Microbiol 1989;27:1471–1476.10.1128/jcm.27.7.1471-1476.1989CrossRefGoogle ScholarPubMed
6. Thornsberry, C, McDougal, LK. Successful use of broth microdilution in susceptibility tests for methicillin-resistant (heteroresistant) staphylococci. J Clin Microbiol 1983;18:1084–1091.10.1128/jcm.18.5.1084-1091.1983CrossRefGoogle ScholarPubMed
7. Simmons, BP, Munn, C, Gelfand, M. Toxic shock in a hospital employee due to methicillin-resistant Staphylococcus aureus . Infect Control Hosp Epidemiol 1986;7:350. Letter.10.1017/S0195941700064444CrossRefGoogle Scholar
8. Ward ‘IT Comparison of in vitro adherence of methicillin-sensitive and methicillin-resistant Staphylococcus aureus to human nasal epithelial cells. J Infect Dis 1992;166:400–404.10.1093/infdis/166.2.400CrossRefGoogle Scholar
9. Opal, SM, Mayer, KH, Stenberg, MJ, et al. Frequent acquisition of multiple strains of methicillin-resistant Staphylococcus aureus by healthcare workers in an endemic hospital environment. Infect Control Hosp Epidemiol 1990;11:479–485.10.1086/646215CrossRefGoogle Scholar
10. Sheagren, JN. Staphylococcus aureus: the persistent pathogen (first of two parts). N Engl J Med 1984;310:1368–1373.10.1056/NEJM198405243102107CrossRefGoogle ScholarPubMed
11. Chow, JW, Yu, VL. Staphylococcus aureus nasal carriage in hemodialysis patients: its role in infection and approaches to prophylaxis. Arch Intern Med 1989;149:1258–1262.10.1001/archinte.1989.00390060012003CrossRefGoogle ScholarPubMed
12. Peacock, JE, Moorman, DR, Wenzel, RP, Mandeli, GL. Methicillin-resistant Staphylococcus aureus: microbiologic characteristics, antimicrobial susceptibilities, and assessment of virulence of an epidemic strain. J Infect Dis 1981;144:575–582.10.1093/infdis/144.6.575CrossRefGoogle ScholarPubMed
13. Mulligan, ME, Murray-Leisure, KA, Ribner, B, et al. Methicillin-resistant Staphylococcus aureus: a consensus review of the pathogenesis and epidemiology with implications for prevention and management. Am J Med 1993;94:313–328.10.1016/0002-9343(93)90063-UCrossRefGoogle ScholarPubMed
14. Brennen, C, Muder, RR. Conjunctivitis associated with methicillin-resistant Staphylococcus aureus in a long-term care facility. Am J Med 1990;88:5–14N-5-17N.Google ScholarPubMed
15. Fleischer, AB, Hoover, DL, Khan, JA, Parisi, JT, Burns, RP. Topical vancomycin formulation for methicillin-resistant Staphylococcus epidermidis blepharoconjunctivitis. Am J Ophthalmol 1986;101:283–287.10.1016/0002-9394(86)90820-2CrossRefGoogle ScholarPubMed