Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-28T11:31:35.358Z Has data issue: false hasContentIssue false

Acquisition of Methicillin-Resistant Staphylococcus aureus in the Acute Care Setting: Incidence and Risk Factors

Published online by Cambridge University Press:  02 January 2015

Christophe Rioux
Affiliation:
Infectious Diseases Unit, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, and, University Paris VII, Paris, France
Laurence Armand-Lefevre
Affiliation:
Bacteriology Laboratory, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, and, University Paris VII, Paris, France
Wafaa Guerinot
Affiliation:
Hospital Infection Unit, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, and, University Paris VII, Paris, France
Antoine Andremont
Affiliation:
Bacteriology Laboratory, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, and, University Paris VII, Paris, France
Jean-Christophe Lucet*
Affiliation:
Hospital Infection Unit, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, and, University Paris VII, Paris, France
*
Unité d'Hygiène et de Lutte contre l'Infection Nosocomiale, GH Bichat- Clauc Bernard, 75877 Paris Cedex 18, France ([email protected])

Abstract

Our objective was to assess the incidence of and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) acquisition among patients in acute care wards. For 5 months, patients were screened for MRSA colonization at admission and at discharge. At admission, 6.6% of patients had cultures positive for MRSA, and 3.1% of patients who had tested negative for MRSA on admission had cultures positive for MRSA at discharge. Only the presence of chronic skin breaks at admission was independently associated with MRSA acquisition.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Graffunder, EM, Venezia, RA. Risk factors associated with nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection including previous use of antimicrobials. J Antimicrob Chemother 2002;49:9991005.Google Scholar
2.Muller, AA, Mauny, F, Bertin, M, et al.Relationship between spread of methicillin-resistant Staphylococcus aureus and antimicrobial use in a French university hospital. Clin Infect Dis 2003;36:971978.CrossRefGoogle Scholar
3.Weber, SG, Gold, HS, Hooper, DC, Karchmer, AW, Carmeli, Y. Fluoroquinolones and the risk for methicillin-resistant Staphylococcus aureus in hospitalized patients. Emerg Infect Dis 2003;9:14151422.Google Scholar
4.Lucet, JC, Grenet, K, Armand-Lefevre, L, et al.High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategies. Infect Control Hosp Epidemiol 2005;26:121126.CrossRefGoogle ScholarPubMed
5.Davis, KA, Stewart, JJ, Crouch, HK, Florez, CE, Hospenthal, DR. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent MRSA infection. Clin Infect Dis 2004;39:776782.CrossRefGoogle ScholarPubMed
6.Harbarth, S, Sax, H, Fankhauser-Rodriguez, C, Schrenzel, J, Agostinho, A, Pittet, D. Evaluating the probability of previously unknown carriage of MRSA at hospital admission. Am J Med 2006;199:275.Google Scholar
7.Fishbain, JT, Lee, JC, Nguyen, HD, et al.Nosocomial transmission of methicillin-resistant Staphylococcus aureus: a blinded study to establish baseline acquisition rates. Infect Control Hosp Epidemiol 2003;24:415421.Google Scholar
8.Troillet, N, Carmeli, Y, Samore, MH, et al.Carriage of methicillin-resistant Staphylococcus aureus at hospital admission. Infect Control Hosp Epidemiol 1998;19:181185.Google Scholar
9.Jernigan, JA, Pullen, AL, Flowers, L, Bell, M, Jarvis, WR. Prevalence of and risk factors for colonization with methicillin-resistant Staphylococcus aureus at the time of hospital admission. Infect Control Hosp Epidemiol 2003;24:409414.Google Scholar
10.Crowcroft, NS, Ronveaux, O, Monnet, DL, Mertens, R. Methicillin-resistant Staphylococcus aureus and antimicrobial use in Belgian hospitals. Infect Control Hosp Epidemiol 1999;20:3136.Google Scholar