Comparing eight post-communist semi-presidential systems (Bulgaria, Croatia, Lithuania, Moldova, Poland, Romania, Ukraine and Russia), comprising a total of 65 instances of intra-executive coexistence between 1991 and 2007, this article asks to what extent and in what ways president–cabinet conflicts increase the risk of cabinet instability. Previous studies of intra-executive conflicts in semi-presidential regimes have mainly been occupied with explaining why conflicts occur in the first place, and have neglected the question of how such conflicts are actually related to political outcomes. The present empirical investigation demonstrates that the occurrence of intra-executive conflict in transitional semi-presidential systems is likely to produce high rates of cabinet turnover.