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Multiple gene control of the tRNA aminoacylating system in Drosophila melanogaster*

Published online by Cambridge University Press:  14 April 2009

Raymond W. Rose  and
Ralph Hillman
Raymond W. Rose
Affiliation:
Biology Department, Temple University, Philadelphia, Pa., U.S.A.
Ralph Hillman
Affiliation:
Biology Department, Temple University, Philadelphia, Pa., U.S.A.
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Summary

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The stimulation of in vitro tRNA aminoacylation by post-microsomal supernatant enzymes isolated from Abnormal Abdomen (A53g) adult flies is a function of the residual genome of these flies rather than of the major mutant gene, A53g. Genes controlling this stimulation are located on the X chromosome as well as on the autosomes. These observations are discussed in terms of the phenotypic effect of the major mutant gene in response to changes in protein synthesis which are under the control of modifier genes responsible for aberrant genetic translation mechanisms.

Type
Research Article
Information
Genetics Research , Volume 21 , Issue 3 , June 1973 , pp. 239 - 245
Copyright
Copyright © Cambridge University Press 1973

References

REFERENCES

Fraser, A. (1967). Variation of scutellar bristles in Drosophila. XV. Systems of modifiers. Genetics 57, 919–934.CrossRefGoogle ScholarPubMed
Hillman, R. (1973). Genetic and environmental control of a continuous trait, Abnormal-abdomen in Drosophila melanogaster. Genetical Research. (In press.)CrossRefGoogle Scholar
Hunt, D. M. (1969). Gene–environment interactions of the eye-gone mutant in Drosophila melanogaster and a comparison with eyeless. Genetical Research 13, 313–320.CrossRefGoogle Scholar
Hunt, D. M. & Burnet, B. (1969). Gene–environment interactions of the eyeless mutant in Drosophila melanogaster. Genetical Research 13, 251–265.CrossRefGoogle ScholarPubMed
Rose, R. & Hillman, R. (1969). In vitro studies of protein synthesis in Drosophila. Biochemical and Biophysical Research Communications 35, 197–200.CrossRefGoogle ScholarPubMed
Sang, J. & Burnet, B. (1963). Environmental modification of the eyeless phenotype in Drosophila melanogaster. Genetics 48, 1683–1699.CrossRefGoogle ScholarPubMed
Spofford, J. B. (1956). The relationship between expressivity and selection against eyeless in Drosophila melanogaster. Genetics 41, 938–959.CrossRefGoogle Scholar
Wittman, K. S. & Hamburgh, M. (1968). The development and effect of genetic background on expressivity and penetrance of the brachyury mutation in the mouse: a study in developmental genetics. Journal of Experimental Zoology 168, 137–146.CrossRefGoogle Scholar