Article contents
Altered instability due to genetic changes in a duplication strain of Aspergillus nidulans
Published online by Cambridge University Press: 14 April 2009
Summary
Strains of Aspergillus nidulans with a duplicate segment are mitotically unstable; they produce phenotypically improved variants following deletions in either duplicate segment, and morphologically deteriorated types. The number of variants produced is characteristic of each duplication strain under the same conditions. After ultraviolet treatment two variants, one more stable and the other less stable than the original strain, were selected. Genetic analysis showed that the increased instability in the less stable variant was due to a translocation involving linkage groups V and VIII. The increased stability of the more stable variant was due to a recessive factor (stf–1) located in linkage group VIII. In the homozygous condition this factor also reduces the number of sectors in a diploid strain. The possible genetic mechanisms explaining the instability alterations are discussed.
- Type
- Research Article
- Information
- Copyright
- Copyright © Cambridge University Press 1975
References
REFERENCES
- 7
- Cited by