Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-24T17:11:30.012Z Has data issue: false hasContentIssue false
  • English
  • Français

Additive effects of the genes tabby and crinkled on tooth size in the mouse

Published online by Cambridge University Press:  14 April 2009

J. A. Sofaer
J. A. Sofaer
Affiliation:
University of Edinburgh, Department of Oral Medicine and Oral Pathology, Edinburgh EH1 1NR Department of Human Genetics, Western General Hospital, Edinburgh EH4 2XU
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The semi-dominant X-linked gene tabby (Ta) in the mouse and its recessive autosomal mimic crinkled (cr) produce the same mutant syndrome involving abnormalities of the hair, teeth and certain exocrine glands. Previous work has provided some indication of interaction between these loci in terms of vibrissa number. The results of the present study demonstrate that, for tooth size, mice doubly heterozygous for tabby and crinkled show a more extreme phenotype than either heterozygotes for tabby or crinkled alone.

Type
Research Article
Information
Genetics Research , Volume 33 , Issue 2 , April 1979 , pp. 169 - 174
Copyright
Copyright © Cambridge University Press 1979

References

REFERENCES

Bader, B. S. (1965). A partition of variance in dental traits of the house mouse. Journal of Mammalogy 46, 384–388.CrossRefGoogle ScholarPubMed
Cattanach, B. M. (1975). Private communication. Mouse News Letter 53, 29.Google Scholar
Crocker, A. J. M. (1978). Private communication. Mouse News Letter 59, 20–21.Google Scholar
Falconer, D. S. (1953). Total sex-linkage in the house mouse. Zeitschrift für indukt. Abstammungsund Vererbungslehre 85, 210–219.Google ScholarPubMed
Falconer, D. S., Fraser, A. S. & King, J. W. B. (1951). The genetics and development of ‘crinkled’, a new mutant in the house mouse. Journal of Genetics 50, 324–344.CrossRefGoogle ScholarPubMed
Fraser, A. S., Nay, T. & Kindred, B. M. (1959). Variation of vibrissa number in the mouse. Australian Journal of Biological Sciences 12, 331–339.CrossRefGoogle Scholar
Grüneberg, H. (1965). Genes and genotypes affecting the teeth of the mouse. Journal of Embryology and Experimental Morphology 14, 137–159.Google ScholarPubMed
Grüneberg, H. (1966 a). The molars of the tabby mouse, and a test of the ‘single-active X-chromosome’ hypothesis. Journal of Embryology and Experimental Morphology 15, 223–244.Google Scholar
Grüneberg, H. (1966 b). More about the tabby mouse and about the Lyon hypothesis. Journal of Embryology and Experimental Morphology 16, 569–590.Google ScholarPubMed
Grüneberg, H. (1971). The glandular aspects of the tabby syndrome in the mouse. Journal of Embryology and Experimental Morphology 25, 1–19.Google ScholarPubMed
Kindred, B. M. (1961). A maternal effect on vibrissa score due to the tabby gene. Australian Journal of Biological Sciences 14, 627–636.CrossRefGoogle Scholar
Kindred, B. M. (1967). The expression of the tabby and crinkled genes in different genetic backgrounds in the mouse. Genetics 55, 173–178.CrossRefGoogle ScholarPubMed
Mayer, T. C., Miller, C. K., & Green, M. C. (1977). Site of action of the crinkled (cr) locus in the mouse. Developmental Biology 55, 397–401.CrossRefGoogle ScholarPubMed
Roberts, B. C. (1966). Private communication. Mouse News Letter 35, 24.Google Scholar
Sofaer, J. A. (1968). Ph.D. thesis, University of Edinburgh.Google Scholar
Sofaer, J. A. (1969 a). Aspects of the tabby-crinkled-downless syndrome. I. The development of tabby teeth. Journal of Embryology and Experimental Morphology 22, 181–205.Google ScholarPubMed
Sofaer, J. A. (1969 b). Aspects of the tabby-crinkled-downless syndrome. II. Observations on the reaction to changes of genetic background. Journal of Embryology and Experimental Morphology 22, 207–227.Google ScholarPubMed
Sofaer, J. A. (1974). Differences between tabby and downless mouse epidermis and dermis in culture. Genetical Research 23, 219–225.CrossRefGoogle ScholarPubMed
Sofaer, J. A. (1975). Interaction between tooth germs and the adjacent dental lamina in the mouse. Archives of Oral Biology 20, 57–61.CrossRefGoogle ScholarPubMed
Sofaer, J. A. (1977). The teeth of the ‘sleek’ mouse. Archives of Oral Biology 22, 299–301.CrossRefGoogle ScholarPubMed
Stevens, L. C. (1963). Private communication. Mouse News Letter 29, 40.Google Scholar