Fatigue is of great clinical and investigational importance. It is a prevalent symptom in general population and a central symptom in many diseases, for example, cancer, ischaemic heart disease and depression. Besides, it's a side effect of many medical treatments. Fatigue has been shown to have a substantial impact on patients’ self care activities and, overall quality of life.

To compare levels of the various aspects of fatigue in three different populations.

To see if diagnosis is a significant predictor for fatigue.

We conducted a survey in a random sample of 69 patients with diabetes Mellitus (DM), 114 psychiatric outpatients (PO) and 383 healthy adults (C), using the Multidimensional Fatigue Inventory (MFI-20). ANOVA test was used to reveille the statistical significance between the groups in all levels of fatigue.

The control group had a significant difference to the PO and DM patients in physical fatigue (MDPO = -3.835 p < .001), (MDDM. = -2.745p< .001), in reduced activity (MD PO = -3.719 p < .001), (MDDM = -3.155 p < .001) and reduced motivation (MDPO = -3.569 p < .001), (MDDM = -2.349 p < .001). Psychiatric outpatients had a significant difference with DM patients and control in general fatigue (MDC = -4.135 p< .001), (MDDM. = -3.835 p < .001) and in mental fatigue (MDC = 4.638 p < .001), (MDDM. = 4.346 p < .001).

Analysis shows that both psychiatric outpatients and patients with DM experience fatigue in all aspects of the measurement as expected, in a statistical significant level compared to the general population.

Burnout is a syndrome consisting of physical and mental exhaustion and depersonalization. Work burn out may be caused by job specification and environment. Medical and paramedical staff because of their job is at high risk and burn out is more common in this group.

In this research 104 nurse including 52 nurses from psychiatry ward and 52 nurses from other hospital wards were randomly selected and evaluated for signs of burn out, anxiety, depression. We applied maslach (MBI) questionnaire to assess the prevalence of burn out, beck questionnaire for prevalence of depression and Hamilton questionnaire for anxiety.

The results showed no significant differences in the average grades of work burn out, depression, anxiety among the nurses serving psychiatry wards and other hospital wards.

As a result being in contact with psychiatric patient cannot essentially lead to anxiety and depression in their caring nursed and so psychological disorder are not transmissible.

Positive affect (PA) is correlated to several positive outcomes and might be a constituent of happiness (Lyubomirsky et al., 2005).

To investigate the correlates of PA in pregnancy and postpartum.

397 pregnant women (T0) were also followed at 3 months postpartum (T1). At both time-points, they completed a questionnaire, the Postpartum Depression Screening Scale (PDSS), the Profile of Mood States (POMS), and were also interviewed with some sections of the Diagnostic Interview for Genetic studies (DIGS). Descriptive and correlation analyses were performed.

T0/T1 PA scores were correlated (p< .01). T0 PA was associated with fewer children, and T1 PA with a concurrent better self-reported health (p< .05). PA at T0/T1 was associated with nulliparity (p< .05/p< .01), mother's age (younger) (p< .05/p< .01). PA at T0/T1 was associated with lower levels of perceived life stress (p< .01); better life quality (p< .01); more social support (p< .01); lower levels of anxiety trait, depressive/anxious emotional states (p< .01), depressive symptoms (p< .01), and suicide ideation (p< .01); less self-reported maternal sleep difficulties and lower interference of it on their mood and working functioning. Moreover, PA assessed at pregnancy was associated with these variables at postpartum. PA at T1 was associated with a better perception of the infant as having less feeding/sleeping/and behavior problems.

PA is a protective emotional trait, a good indicator of physical/mental health, and well-being in perinatal period. Mother's PA influences her perception of the infant temperament and may contribute positively to the dyadic interaction.

The holy Quran is the curative that after its cure,there is no fear of disease anymore. One of the miracles of Quran is its effect on sevice and medical care duties.

Regarding the key role of nurses in offering health service to patients and the importance of the nurses' mental health, thisc study was conducted.

To assess the effect of Quran on the mental health of nurses.

This educational trial was done on 55 nurses at educational hospitals of Arak University of Medical Sciences through randomized simple sampling. Intervention was attendance in the workshop of familiarity with Quran. Before and after intervention, the GHQ-28 questionnaire was completed by the participants.Data were analyzed by descriptive statistics, paired t-test, and Chi square.

The mean age of the nurses was 34.45 ± 6.3 years. 30 participants (68.2%)were married. the mean mental health scores before and after intervention were 27.75 ± 9.76 and 22.34 ± 7.83 respectively which indicated the significant difference (P < 0.014).

The intervention has been effective in reducing mental health scores and somehow, in improving the nurses' mental health status. on the other hand, participation in the familiarity with Quran workshop can improve the nurses' mental health.

Based on clinical impressions personality disorders (PDs) and psychiatric disorders characterized by body image disorder (BID) have been suggested to be relatively common in cosmetic surgery settings and closely associated with patient's post-operative dissatisfaction despite technically satisfactory surgical results, leading to problems for both patients and surgeons.

The study investigated the prevalence and the comorbidity between BID and PDs in patients seeking cosmetic surgery, as well as the impact of the following clinical variables on patient's post-operative dissatisfaction: number of pathological personality traits, severity of body uneasiness and worries about particular body parts and intensity of these concerns.

Two hundred fifty patients scheduled for profile, breast and body contouring cosmetic surgery from two Italian hospitals (90% F; Mage = 31.5 ± 4.0) completed the Body Uneasiness Test (BUT), the Personality Diagnostic Questionnaire-4+ (PDQ-4) before surgery and a measure of patient satisfaction 13 months after surgery.

18.9% of subjects, had at least 1 PD (cluster B and C's in particular). Using the BUT cut-off score as a marker of clinical significance, 48.8% of subjects had a BID, and all PD patients showed comorbidity with BID. The number of pathological personality traits, the severity of body uneasiness and the intensity of worries about body parts showed a predictive power on patients’ post-operative dissatisfaction.

PDs and BID are common in cosmetic surgery settings. Our data suggest also that a thorough pre-operative clinical assessment may allow the pre-operative identification of patients with low levels of post-operative satisfaction.

Cognitive impairment is a core feature of schizophrenia, associated with significant social and functional impairment. Schizophrenia has also been associated with inflammation and immune changes. Recently it has been showed that IL-6, a pro-inflammatory cytokine, was associated with cognitive impairment.

The aim of this study was to assess the associations between a pro-inflammatory cytokines (IL-6) and an anti-inflammatory cytokine (IL-4) with social cognition in a sample of stable patients with schizophrenia.

Social cognition was assessed using the Face Emotion Identification Task (FEIT) and the Hinting Task in 29 stable outpatients with schizophrenia. Blood was collected and cytokines (IL-4, IL-6) assays were realized (CBA method).

IL-6 levels showed a significant inverse correlation with FEIT global score (p = 0.019, rho = -0.475) and a trend of significant inverse correlation with the Hinting Task (p = 0.079, rho = -0.332). However, IL-4 levels showed no significant association with the FEIT or the Hinting task (rho = 0.079 and 0,121; respectively).

Elevated IL-6 levels seem to play a role in social cognitive impairment in stable patients with schizophrenia. These results should be interpreted with caution due to the limited number of participants in the study.

Positive influence of emotional intelligence (EI) on psychological functions is fast growing in many aspects of social life and higher levels of emotional intelligence can be important in human's behavior. So this study investigated emotional intelligence in addicted and nonaddicted people.

In sampling process a total of 73 addicted people and 73 non-addicted people were randomly selected. All participants were requested to complete Schutte's Self- Report E / I Test (SSREIT).

Findings indicated significant differences between two groups in components of emotional intelligent. Nonaddicted people had more scores in appraisal of emotion, utilization of emotion and general score of emotional intelligence than addicted people.

Findings indicates that applying of plans in the field of increasing emotional intelligent can help people with positive attitudes to addiction in order to manage the bad problems and event and as a result reduce tendency to addiction.

Schizophrenia (SKZ) is a chronic, disabling and incapacitating psychiatric disorder. In addition to the traditional symptomes of schizophrenia, the suffering of this patients can be expressed through a set of cognitive complaints

To determe the factors associated with subjective cognitive complaints in schizophrenia

We conducted a cross-sectional descriptive and analytical study among a sample of of 72 patients followed in psychiatric outpatient of Hefi chaker university hospital in sfax. We used the SSTIC scale to determine subjectif complains ans the PANSS to evalue positif and negatif symptomes

The mean age of our popularion was 46.83± 11.6 years. The patients had a low socio-economic level in 70.1%. They were unemployed in 46.9%, consumed alcohol in 23.6% and consumed tobacco in 58,6% of the cases. the total score on the PANSS scale was 46, distributed as follows: 9 for positive symptoms, 17 for negative symptoms and 22 for total psychopathological assessment. They had an average score of 25 on the total SSTICS score Factors significantly correlated with subjective cognitive complaints were: low socio-economic level (p=0.04), lack of occupation (p=0.001), alcoholism (p=0.001), smoking (p=0.01) and presence of negative symptoms (p=0.00).

This study demonstrates that socio-demographic characteristics and the predominance of negative signs may increase the subjectif cognitif complains in schizophrenia. The recognition of these associations by the psychiatrist can have an important implication in the therapeutic management.

Clinical, epidemiological and basic research studies have confirmed that estradiol can have protective effects in schizophrenic psychoses. At the same time many patients with schizophrenic psychoses – even antipsychotic naïve at-risk mental state (ARMS) patients show hyperprolactinemia and gonadal dysfunction with estrogen deficiency in women and possibly testosterone deficiency in men.

To investigate the relation between the stress hormone prolactin and the sex hormones estradiol in women and testosterone in men in emerging psychosis.

Forty-seven antipsychotic-naïve ARMS (38 men and 9 women) and 17 antipsychotic-naive first episode psychosis (FEP) (14 men and 3 women) patients were recruited via the Basel Früherkennung von Psychosen (FePsy) study. Blood was taken under standardized conditions between 8 and 10 am after an overnight fast and 30 minutes of rest. We performed a linear regression model to evaluate the association between prolactin and sex hormones including age and current antidepressant use as covariates.

In women, estradiol was negatively associated with prolactin (β = −1.28, P = 0.01) whereas in men there was a positive association of testosterone with prolactin (β = 0.52, P = 0.031).

The often observed estrogen deficiency in women with psychosis could therefore be explained by the stress hormone prolactin suppressing the gonadal axis already in very early untreated stages of the emerging disease.

In ARMS or FEP men prolactin does not seem to influence the gonadal axis in the same way as in women.

The authors have not supplied their declaration of competing interest.

The progressive increase in the prevalence of anxiety disorders in advanced ages advises the extensive use of of screening measurements in this population, that, everywhere in the world, has raised numerically.

The aim of this study was to examine the psychometric properties of a Portuguese version of the Geriatric Anxiety Inventory-Short Form (GAI-SF, 5-item format) in a sample of 932 elders.

Quantitative and cross-sectional study with descriptive and correlational planning. Translation and back-translation was performed by language proficiency experts. The reliability was assessed through Cronbach's alpha coefficient and the factorial validity through Principal Components Analysis. The convergent validity was conducted with the Geriatric Depression Scale (GDS) and the Positive and Negative Affects Scale (PANAS-Negative sub-scale), while discriminant validity was performed with the PANAS-Positive sub-scale and the Satisfaction With Life Scale (SWLS). A Confirmatory Factor Analysis, using a structural equation modeling, was performed to test the fit of the model with the five items.

The GAI-SF showed good internal consistency (α = 0.77), good convergent, and discriminant validity (p < 0.05). The factorial structure presented a single factor that explained 52% of the variance. The model showed a good fit to the data (χ2= 1.233, TLI = 0.997, CFI = 0.999, RMSEA = 0.020).

The GAI-SF, a brief self-report scale, has good validity and reliability, and factorial qualities adequate to measure anxiety symptoms in epidemiological surveys and in geriatric settings.

The opioid system modulator nalmefeneis the first pharmacological therapy approved in the European Union for reduction of alcohol consumption.

To evaluate the clinical relevance of the reduction of alcohol consumption in patients with at least high drinking risk level at screening and randomisation from the two, identically designed, randomised controlled 6-month studies ESENSE1 (NCT00811720) and ESENSE2 (NCT00812461) of nalmefene versus placebo.

Study medication was taken as-needed. All patients received a motivational and adherence-enhancing intervention (BRENDA). Response criteria were based on alcohol consumption at month 6 and Clinical Global Impression – Severity of Illness/Improvement (CGI-S/I), Short Form Health Survey version 2 (SF-36) mental component summary(MCS) scores at week 24. Clinical relevance was also studied using the Drinker Inventory of Consequences (DrInC), Alcohol Dependence Scale (ADS), and liver function variables.

Pooled study population: 667 patients (placebo N=332; nalmefene N=335). The proportion of responders was higher in the nalmefene group than in the placebo group with odds ratios for response consistently significantly (p<0.05) in favour of nalmefene. The difference in the proportions of responders translated to numbers-needed-to-treat ranging from 6 to 10. Significant differences to placebo (p<0.05) in the SF-36 MCS and physical component summary score, ADS, DrInC, CGI-I/S and liver enzymes further supported the clinical relevance of the treatment effect.

In view of the immense alcohol-related burden to society, the harm to the individual and the large treatment gap partly due to a reluctance to engage in abstinence, the effect of nalmefene is clearly clinically relevant.

Heart failure is a progressive and unpredictable heart disease. How to work with these patients to decrease their psychological distress and promote their self-care behaviors is important. Transition care is the continuity of medical care for heart failure patients returning home from the hospital. Intervention through transition care may improve the continuity of medical care for patients with heart failure but it has not been examined in clinical settings in Taiwan.

The aims of this study were to explore the effects of a newly developed transition care program on depression, self-efficacy, and self-care behavior of heart failure patients.

Using an experimental research design and block randomization, participants were divided into the experimental group (received transition care and routine care) and the control group (received routine care only). The Patient Health Questionnaire-9 (PHQ-9), the General Self-Efficacy Scale (GSES), and the Self-Care of Heart Failure Index (SCHFI version 6.2) were used to collect data before discharge and the first month after discharge.

A total of 20 patients with heart failure were recruited. No significant differences were found between the experimental (n=10) and control groups (n=10) in the degree of depression (Z=-.077, p=.938), self-efficacy (Z=-1.214, p=.225), and three self-care behaviors subscales (self-care maintenance Z= -1.214, p=.225; self-care management Z= -.401, p=.689; self-care confidence Z=-.436, p=.663) at discharge. After the one-month posttest, only self-efficacy (Z=-2.545, p=.011) and three self-care behaviors subscales (self-care maintenance Z=-3.097, p=.002; self-care management Z= -2.595, p=.009; self-care confidence Z=-3.671, p<.001) reached a statistical difference between the two groups.

Based on the preliminary results, heart failure patients can improve their self-care behavior and self-efficacy but not depression through transitional care intervention.

None Declared

The COVID-19 pandemic, and the consequent recession, have caused a decline in the job market, with the resultant job insecurity increasing the risk of depression. While this affected all genders, suicidal thoughts were observed to be more common among women than men, suggesting that the impact of unemployment on depression varies by gender, with gender differences affecting the outcome of depression.

This study aims to verify the moderating effect of gender on the structural relationship between unemployment, depression, and suicide during the COVID-19 pandemic by using online search trend data.

The study utilized the search trend data from Naver’s Data Lab service, by analyzing the searches of men and women under 65, between March, 2020 and September 12, 2021. The search terms were “unemployment,” “depression,” and “suicide.” The analysis examined 1121 searches using the Model 7 research model through the SPSS Process Macro to verify the moderating effect of gender on the mediating pathways for unemployment, depression, and suicide.

We observed that searches for “unemployment” significantly increased with searches for “depression” (B=1.860, p<.001) and “suicide” (B=.860, p<.001). The analysis further revealed that the correlation between the increase in searches relating to depression and unemployment was seen more in women than men. This resulted in an accompanying increase in the volume of searches for suicide (B=2.341, p<.001).

The job insecurity caused by the COVID-19 pandemic led to varying degrees of depression according to gender. Thus, social security measures related to unemployment, depression, and suicide interventions require a gender-specific approach.

No significant relationships.

Today's, families of individuals with bipolar disorders are actively participating in the care of their relative. Successful management of bipolar disorder in the community relies significantly on family caregivers. The need and experiences of such caregivers have been little studies with respect to bipolar disorder.

The aim of the study was to identify of family caregivers needs of patients with bipolar disorder.

In a qualitative research of phenomenological methodology, the family member’s caregivers of bipolar disorder in farshian psychiatric hospital in Hamedanl were selected by purposive sampling in the year 2010. By reaching data saturation the number of participant was 12. Data were gathered through in-depth interviews and analyzed by “Van manen” method.

Five main themes were identified in this study analysis: educational needs, consult needs, economical needs, care and nursing needs and supports needs.

Identified the need of family member caregiver with bipolar disorder patient for mental health services to be helped and to identify the specific caring interventions that are effective in helping to sustain family caregiving.