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Statistical comparison of transition sleep variables in depressed and normal subjects

Published online by Cambridge University Press:  16 April 2020

G Iorio ,
F Marciano ,
M Martino  and
D Kemali
G Iorio
Affiliation:
Department of Psychiatry, First Medical School, University of Naples
F Marciano*
Affiliation:
Istituto di Cibernetica del CNR, Via Toiano 6, 80072 Arco Felice, Naples, Italy
M Martino
Affiliation:
Department of Psychiatry, First Medical School, University of Naples
D Kemali
Affiliation:
Department of Psychiatry, First Medical School, University of Naples
*
*Correspondence and reprints.
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Summary

We present the values for the amount of transitions, for the total stage duration and for the first time of occurrence (latency) of a stage. A test aimed at evaluating probability values for the transition from one sleep stage to another was applied to the hypnograms of ten patients with endogenous depression and of ten normal controls. Sleep data (EEG, EMG, EOG) of each subject were recorded on magnetic tape and paper for three consecutive nights. Following sleep stage classification, portions of hypnograms of 480 min, further divided into sub-periods, were retained for the purpose of the test. The results proved that significant differences between depressed and control subjects exist among the data corresponding to various sleep stages. These findings also provided useful statistical indications in order to reduce the amount of computing needed by an automatic classifier.

Keywords

sleephypnogramdepressionstatistical comparison
Type
Original article
Information
European Psychiatry , Volume 9 , Issue 2 , 1994 , pp. 95 - 100
Copyright
Copyright © European Psychiatric Association 1994

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References

Beersma, DGMDaan, SHoofdakker van den, RH. Distribution of REM latencies and other sleep phenomena in depression as explained by a single ultradian rhythm disturbance. Sleep 1984;7(2):126-36CrossRefGoogle ScholarPubMed
Burg van den, WHoofdakker van den, RH. Sleep disturbance in serious depression.In: Popoviciv, LAsgian, BBadiu, G eds. Sleep 78. Basel: Karger, 1980;130-56Google Scholar
Char-nie, Chen. Sleep, depression and antidepressants. Br J Psychiatry 1979;135:385–402Google Scholar
Coble, PAKupfer, DJShaw, DH. Distribution of REM latency in depression. Biol Psychiatry 1981;16:453-64Google ScholarPubMed
Emslie, GJRush, AJWeineberg, WA. Children with major depression show reduced rapid eye movement latencies. Arch Gen Psychiatry 1990;47:119-23CrossRefGoogle ScholarPubMed
Gaillard, JMIorio, GBlois, RRichard, JTissot, R. Temporal organization of paradoxical sleep in depressed patients with reference to brain catecholaminergic activity. Res Commun Psychol Psychiatry Behav 1981a;6(2):141-61Google Scholar
Gaillard, JMIorio, GBlois, RRichard, JTissot, R. Modifications of sleep in depressed patients: possible physiopathological implications. Adv Biol Psychiatry 1981b;6:81-6CrossRefGoogle Scholar
Gaillard, JMIorio, GCampajola, PKemali, D. Temporal organization of sleep in schizophrenics and patients with obsessive-compulsive disorders. Adv Biol Psychiatry 1984;15:76–83CrossRefGoogle Scholar
Giles, SRoffwarg, HRush, AJ. A cross-sectional study of the effects of depression on REM latency. Biol Psychiatry 1990;28:697–704CrossRefGoogle ScholarPubMed
Gillin, CDuncan, WPettigrew, KFrankel, BSnyder, F. Successful separation of depressed, normal and insomniac subjects by EEG sleep data. Arch Gen Psychiatry 1979;36:85–90CrossRefGoogle ScholarPubMed
ICD (9th version) Mental disorders, glossary and guide to their classification in accordance with the ninth revision of the international classification of diseases, World Health Organisation, GenevaGoogle Scholar
Kupfer, DJFoster, FGCoble, PMcPartland, RJUlrich, RF. The application of EEG sleep for the differential diagnosis of affective disorders. Am J Psychiatry 1978;135(1):69–74Google ScholarPubMed
Kupfer, DJ. Application of EEG sleep for the differential diagnosis and treatment of affective disorders. Pharmacopsychiatry 1978;1:17–26CrossRefGoogle Scholar
Kupfer, DGillin, DCoble, PSpiker, DShaw, DHolzer, B. REM sleep, NAPS and depression. Psychiatry Res 1981 ;5:195–203CrossRefGoogle ScholarPubMed
Kupfer, DJShaw, DHUlrich, RCoble, PASpiker, DG. Application of automated REM analysis in depression. Arch Gen Psychiatry 1982;39:569-73CrossRefGoogle ScholarPubMed
Kupfer, DJFrank, EGrochocinski, VJGrecor, MMcEachran, AB. EEG sleep profiles in recurrent depression. Arch Gen Psychiatry 1988;45:678-81CrossRefGoogle ScholarPubMed
Lang, HBurr, WVon Aswege, J. Sleep stage shifts in depressive illness. Biol Psychiatry 1976;11:239-43Google Scholar
Lowy, FHGleghorn, JMMcClure, DS. Sleep patterns in depression. J Nerv Ment Dis 1971;1563:10–26CrossRefGoogle Scholar
Maggini, GGuazzelli, MRocca, RPieri, MLattanzi, L. REM latency in depressed and schizophrenic patients.In: Koella, WPRuther, ESchulz, H eds. Sleep 84. Stuttgart: Fisher Verlag, 1985;433-45Google Scholar
Schulz, H. Sleep in affective disorders. An experimental study in depressed and remitted patients.In: Smirne, SFranceschi, MFerini, LStrambi, L eds. Sleep in Medical and Neuropsychiatric Disorders. Milan: Masson, 1988;75–86Google Scholar
Spitzer, RLEndicott, JRobins, E. The research diagnostic criteria, rationale and reliability. Arch Gen Psychiatry 1978;35:773-9CrossRefGoogle ScholarPubMed
Taub, JMBerger, RJ. Sleep stage patterns associated with acute shifts in the sleep-wakefulness cycle. Electroencephalogra Clin Neuraphysiol 1973;35:613-19CrossRefGoogle ScholarPubMed
Vogel, GWVogel, FMcAbee, RSThurmond, AJImprovement of depression by REM sleep deprivation. Arch Gen Psychiatry 1980;37:237-53CrossRefGoogle ScholarPubMed
Zarcone, VPBenson, KLBerger, PA. Abnormal rapid eye movement latencies in schizophrenia. Arch Gen Psychiatry 1987;44:45-8CrossRefGoogle Scholar
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