P01-98 - Influence of the Commorbid Posttraumatic Stress Disorder on the Clinical Presentation of the Depressive Epizode

Abstract

The objective of the paper is to determine the pattern of influence of the chronic posttraumatic stress disorder on the clinical presentation of the depressive epizode. The focus of investigation is the comparision of the characteristics of the depressive epizode commorbid with chronic posttraumatic stress disorder with the depressive epizode which is a part od the primary depressive disorder.

Method

The investigation included 60 patients. Assessment was made by means of the following instruments:Montgomery-Asberg Depression Rating Scale for DSM-IV (MADRS), Hamilton Rating Scale for Depression (HAMD) and Clinician-Administrated PTSD Scale for DSM-IV (CAPS). The differences between groups were evaluated using Student t test and by means of the correlational analysis of the data with p < 0.05.

Results obtained showed significal clinical severity of the depression commorbid with postraumatic stress disorder. The group of the symptoms: lassitude, inability to feel, suicidal thoughts and inner tension contributed mostly to the global severity of the comorbid clinical depression.

Conclusion

The interpretation of results in the light of patophysiological mechanisms underlying the symptoms will enable the insight onto possible mechanisams of interaction of two disorders. Both classical and current trends of the psychoanalytical thinking, reffering to melanholia and to transformation of the trauma in the internal world, enabled explanation of the deepening of depression observed after ten years follow-up of the traumatized population.