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Negative symptoms of schizophrenia in patients with acute and transient psychotic disorders

Published online by Cambridge University Press:  13 August 2021

G. Aleshkina ,
M. Pugacheva  and
L. Bardenshteyn
G. Aleshkina*
Affiliation:
Department Of Psychiatry And Narcology, A. I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation
M. Pugacheva
Affiliation:
Department Of Psychiatry And Narcology, Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russian Federation
L. Bardenshteyn
Affiliation:
Department Of Psychiatry And Narcology, A. I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

The ICD-10 acute and transient psychotic disorders (ATPD, F23) without symptoms of schizophrenia are considered predominantly reactive psychotic disorders or affective pathology. However, negative symptoms of schizophrenia may be revealed in some of these cases after the psychotic reduction.

Objectives

To investigate the association between the developmental characteristics of psychosis and the negative symptoms detection after the psychotic reduction of ATPD without symptoms of schizophrenia.

Methods

68 adult inpatients with ATPD without symptoms of schizophrenia (F23.0) were examined. Negative symptoms were assessed with the PANSS negative symptom subscale (PANSS-NSS). The sample was divided into two groups: with PANSS-NSS score>14 (n=12) and with PANSS-NSS score≤14 (n=56), respectively. Clinical-psychopathological, psychometric and statistical methods were applied.

Results

The results of the study are presented in Table 1.

Table 1. The ATPD developmental features
FeaturesThe 1st group (n=12)The 2nd group (n=56)Pearson’s contingency coefficient (C)
Males7 (58,3%)37 (66,1%)0.062
Females5 (41,7%)19 (33,9%)0.062
Mean age of psychotic onset, years (М±m)24,9±10,530,8±10,2-
Family history of schizophrenia*4 (33,3%)1 (1,8%)0.418
Poor premorbid social adaptation*5 (41,7%)00.520
Prodromal functional decline*9 (75,0%)4 (7,1%)0.550
Prodromal non-psychotic symptoms9 (75,0%)30 (53,6%)0.163
Associated acute stress4 (33,3%)27 (48,2%)0.113

*p<0,001

Conclusions

The probability of negative symptoms detection in ATPD without symptoms of schizophrenia is relatively strongly associated with the family history of schizophrenia, poor premorbid social adaptation and functional decline prior to the psychotic onset.

Disclosure

No significant relationships.

Keywords

negative symptomsschizophréniaAcute and transient psychotic disorder
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S802
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Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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