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Impact of the WHO depression guideline on patient care by psychiatrists: A randomized controlled trial

Published online by Cambridge University Press:  16 April 2020

Michel Linden ,
Anja Westram ,
Lutz G. Schmidt  and
Clemenz Haag
Michel Linden*
Affiliation:
Research Group Psychosomatic Rehabilitation at the Charité, University Medicine Berlin and the Rehabilitation Centre Seehof, Lichterfelder Allee 55, 14513Teltow/Berlin, Germany
Anja Westram
Affiliation:
Research Group Psychosomatic Rehabilitation at the Charité, University Medicine Berlin and the Rehabilitation Centre Seehof, Lichterfelder Allee 55, 14513Teltow/Berlin, Germany
Lutz G. Schmidt
Affiliation:
Department of Psychiatry, Johannes–Gutenberg Universität, Mainz, Germany
Clemenz Haag
Affiliation:
Organon GmbH Germany, Oberschleissheim, Germany
*
*Corresponding author. Tel.: +049 03328 345678; fax: +049 03328 345555. E-mail address: [email protected] (M. Linden).
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Abstract

Background

Scientific literature reviews aim to summarize the state of knowledge and published empirical evidence. In contrast, medical guidelines are intervention tools that aim to improve physician behaviour and patient outcome. They can have positive effects, but they can also have negative effects. Their effects must be tested by research.

Methods

In a randomized controlled trial, 103 psychiatrists in private practice were either provided with the WHO depression guideline only (information group), or provided with the WHO depression guideline and trained for one day in this guideline (intervention group), or left uninformed (control group). They then treated a total of 497 patients according to individual clinical considerations and the needs of the patients. Observation of routine treatment lasted 12 weeks. Physicians and patients documented the course of illness and treatment, including the patient–physician interaction.

Results

Psychiatrists in the intervention group saw more psychosocial stressors in their patients, prescribed higher dosages of medication, had fewer drop-outs, and rated treatment outcome as better. The ratings of patient–physician interactions indicated more strain in their relationships.

Conclusions

The results show both positive and negative effects of guideline exposure, but only in the training group and not in the information group. Guidelines should be empirically tested before being called “evidence based”. Every guideline should also explain how it can or must be implemented in order to become effective.

Keywords

Treatment guidelinesDepressionRandomized controlled trialEvidence-based medicinePsychiatristsContinuing medical education
Type
Original article
Information
European Psychiatry , Volume 23 , Issue 6 , September 2008 , pp. 403 - 408
Copyright
Copyright © Elsevier Masson SAS 2008

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